Brief Information of the Compound and Protein
Compound Name
6-Substituted 4-Anilinoquinazoline 15
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PubChem ID
SID: 15599932
Canonical SMILES
Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C=C)cc23)c1
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Compound Formula C18H13BrN4O
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.6 nM