Brief Information of the Compound and Protein
Compound Name
N-[4-(3-bromoanilino)-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-6-yl]prop-2-enamide
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PubChem ID
CID: 10530118
SID: 15556106
Canonical SMILES
CN1CCN(CCCOc2cc3ncnc(Nc4cccc(Br)c4)c3cc2NC(=O)C=C)CC1
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Compound Formula C25H29BrN6O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.7 nM