Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R,3S)-N-(4-(3-Bromoanilino)quinazolin-6-yl)-3-(piperidin-1-ylmethyl)oxirane-2-carboxamide
    Show/Hide
 PubChem ID
CID: 45141138
SID: 92391091
Canonical SMILES
Brc1cccc(Nc2ncnc3ccc(NC(=O)[C@@H]4O[C@H]4CN4CCCCC4)cc23)c1
    Show/Hide
Compound Formula C23H24BrN5O2
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
2
IC50 = 44 nM
   TI
   LI
   LO
   TS