Brief Information of the Compound and Protein
Compound Name
4-Anilino quinazoline deriv. 10
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PubChem ID
CID: 324081
SID: 15365678
Canonical SMILES
N(c1ccccc1)c1ncnc2ccccc12
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Compound Formula C14H11N3
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  2
1
IC50 = 344 nM
   TI
   LI
   LO
   TS
2
IC50 = 346 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 346.74 nM