Brief Information of the Compound and Protein
Compound Name
4-N-(3-bromophenyl)-6-[(2-methylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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PubChem ID
CID: 3008961
SID: 15080115
Canonical SMILES
Cc1ccccc1Cc1cc2c(Nc3cccc(Br)c3)nc(N)nc2[nH]1
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Compound Formula C20H18BrN5
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  2
1
IC50 = 9100 nM
   TI
   LI
   LO
   TS
2
IC50 = 9190 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9190 nM