Brief Information of the Compound and Protein
Compound Name
7-methoxy-6-(2-morpholin-4-ylethoxy)-N-(2-phenylcyclopropyl)quinazolin-4-amine
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PubChem ID
CID: 44324869
Canonical SMILES
COc1cc2ncnc(NC3CC3c3ccccc3)c2cc1OCCN1CCOCC1
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Compound Formula C24H28N4O3
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CL000220 KB Homo sapiens (Human)  1
1
IC50 = 570 nM
   TI
   LI
   LO
   TS