Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-2-butenamide
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 PubChem ID
CID: 5329072
SID: 15525188
Canonical SMILES
C\C=C\C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
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Compound Formula C17H14BrN5O
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.5 nM