Brief Information of the Compound and Protein
Compound Name
(3-Chloro-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
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PubChem ID
CID: 9816954
SID: 14775051
Canonical SMILES
Cc1[nH]c2ncnc(Nc3cccc(Cl)c3)c2c1C
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Compound Formula C14H13ClN4
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 27 nM
2 IC50 = 27000 nM