Brief Information of the Compound and Protein
Compound Name
4-N-(3-bromophenyl)-7-chloroquinazoline-4,6-diamine
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PubChem ID
CID: 5328213
SID: 15648143
Canonical SMILES
Nc1cc2c(Nc3cccc(Br)c3)ncnc2cc1Cl
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Compound Formula C14H10BrClN4
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 6.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.607 nM