Brief Information of the Compound and Protein
Compound Name
4-[(3-Bromophenyl)amino]-7-[[3-(4-morpholino)propyl]amino]pyrido[4,3-d]pyrimidine N1 -Oxide
    Show/Hide
PubChem ID
CID: 5328314
SID: 15553930
Canonical SMILES
[O-][N+]1(CCCNc2cc3ncnc(Nc4cccc(Br)c4)c3cn2)CCOCC1
    Show/Hide
Compound Formula C20H23BrN6O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.74 nM
2 IC50 = 0.7413 nM