Brief Information of the Compound and Protein
Compound Name
N*4*-(3-Bromo-phenyl)-N*6*-[3-(4-methyl-piperazin-1-ylamino)-propyl]-pyrido[3,4-d]pyrimidine-4,6-diamine
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PubChem ID
CID: 44377259
Canonical SMILES
CN1CCN(NCCCNc2cc3c(Nc4cccc(Br)c4)ncnc3cn2)CC1
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Compound Formula C21H27BrN8
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 8.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.9 nM