Brief Information of the Compound and Protein
Compound Name
(3-Bromo-phenyl)-(5H-pyrimido[5,4-b]indol-4-yl)-amine hydrochloride
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Canonical SMILES
Brc1cccc(Nc2[nH]cnc3c4ccccc4nc2-3)c1.Cl
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Compound Formula C16H12BrClN4
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 93 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 72 nM