Brief Information of the Compound and Protein
Compound Name
7-N-[2-(1H-imidazol-4-yl)ethyl]-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine
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PubChem ID
CID: 5328331
SID: 15772505
Canonical SMILES
Cc1cccc(Nc2ncnc3cc(NCCc4cnc[nH]4)ncc23)c1
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Compound Formula C19H19N7
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 7.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.244 nM