Protein Information

General Information of the Protein

Protein ID	PT02392
Protein Name	B2 bradykinin receptor
Gene Name	BDKRB2
Secondarily Gene Name	BKR2
Sequence	MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMENSMGTLRTSISVERQIHKLQDWAGSRQ Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor > Family A G protein-coupled receptor > Peptide receptor (family A GPCR) > Short peptide receptor (family A GPCR) > Bradykinin receptor
Function	Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. Show/Hide
Uniprot ID	P30411
Ensembl ID	ENSG00000168398
HGNC ID	HGNC:1030
Subcellular Location	Cell membrane

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000052 , A-431

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0847066 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride Show/Hide	C31H29Cl3N4O4	1
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0943579 Compound Info	4-{(E)-2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide hydrochloride Show/Hide	C30H29BrCl3N5O4	1
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0885378 Compound Info	4-{(E)-2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride Show/Hide	C29H27BrCl3N5O4	1
1	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0945053 Compound Info	(E)-3-(4-Acetylamino-phenyl)-N-({[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-acrylamide hydrochloride Show/Hide	C29H27BrCl3N5O4	1
1	IC50 = 1.6 nM Bioactivity Info	TI LI LO TS
CP0887793 Compound Info	3-(6-Acetylamino-pyridin-3-yl)-N-({[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-acrylamide; Dihydrochloride Show/Hide	C28H27BrCl4N6O4	1
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
CP0885577 Compound Info	(E)-N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(3-methyl-ureido)-phenyl]-acrylamide hydrochloride Show/Hide	C29H28BrCl3N6O4	1
1	IC50 = 2.6 nM Bioactivity Info	TI LI LO TS
CP0885377 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride Show/Hide	C30H28Cl3N5O4	1
1	IC50 = 3.1 nM Bioactivity Info	TI LI LO TS
CP0404246 Compound Info	Firazyr Show/Hide	C59H89N19O13S	1
1	IC50 = 3.3 nM Bioactivity Info	TI LI LO TS
CP0885966 Compound Info	5-{2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid dimethylamide; Dihydrochloride Show/Hide	C29H29BrCl4N6O4	1
1	IC50 = 3.7 nM Bioactivity Info	TI LI LO TS
CP0902615 Compound Info	(E)-N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide hydrochloride Show/Hide	C31H29BrCl3N5O4	1
1	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
CP0902447 Compound Info	(E)-N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-3-(4-methanesulfonylamino-phenyl)-acrylamide hydrochloride Show/Hide	C28H27BrCl3N5O5S	1
1	IC50 = 4.8 nM Bioactivity Info	TI LI LO TS
CP0885937 Compound Info	5-{2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid methylamide; Dihydrochloride Show/Hide	C28H27BrCl4N6O4	1
1	IC50 = 9.1 nM Bioactivity Info	TI LI LO TS
CP0457306 Compound Info	3-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide Show/Hide	C32H30Cl2N4O4	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0943624 Compound Info	(E)-3-[4-(Acetyl-methyl-amino)-phenyl]-N-({[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-acrylamide hydrochloride Show/Hide	C30H29BrCl3N5O4	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0882976 Compound Info	3-[3-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-ureido]-N-(2-methoxy-ethyl)-benzamide hydrochloride Show/Hide	C29H30BrCl3N6O5	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0920265 Compound Info	3-[3-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-ureido]-N,N-dimethyl-benzamide hydrochloride Show/Hide	C28H28BrCl3N6O4	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0392560 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(1,2-dimethyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide Show/Hide	C30H29Cl2N5O4	1
1	IC50 = 43 nM Bioactivity Info	TI LI LO TS
CP0465050 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinazolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide Show/Hide	C30H27Cl2N5O4	1
1	IC50 = 59 nM Bioactivity Info	TI LI LO TS
CP0902432 Compound Info	2-[3-(3-Acetyl-phenyl)-ureido]-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide hydrochloride Show/Hide	C27H25BrCl3N5O4	1
1	IC50 = 61 nM Bioactivity Info	TI LI LO TS
CP0395223 Compound Info	N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-2-[[3-[(2-methoxyacetyl)amino]phenyl]carbamoylamino]-N-methylacetamide Show/Hide	C28H27BrCl2N6O5	1
1	IC50 = 75 nM Bioactivity Info	TI LI LO TS
CP0897038 Compound Info	(Z)-N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-3-phenyl-acrylamide hydrochloride Show/Hide	C27H24BrCl3N4O3	1
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
CP0946107 Compound Info	N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-(3-m-tolyl-ureido)-acetamide hydrochloride Show/Hide	C26H25BrCl3N5O3	1
1	IC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0470615 Compound Info	N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-N-methyl-2-[(2-methylphenyl)carbamoylamino]acetamide Show/Hide	C26H24BrCl2N5O3	1
1	IC50 = 150 nM Bioactivity Info	TI LI LO TS
CP0523171 Compound Info	3-[3-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-ureido]-benzoic acid ethyl ester Show/Hide	C28H26BrCl2N5O5	1
1	IC50 = 150 nM Bioactivity Info	TI LI LO TS
CP0902621 Compound Info	N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-(3-phenyl-ureido)-acetamide hydrochloride Show/Hide	C25H23BrCl3N5O3	1
1	IC50 = 150 nM Bioactivity Info	TI LI LO TS
CP0856319 Compound Info	N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-[3-(3-nitro-phenyl)-ureido]-acetamide hydrochloride Show/Hide	C25H22BrCl3N6O5	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0895135 Compound Info	N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-2-[3-(3-cyano-phenyl)-ureido]-N-methyl-acetamide hydrochloride Show/Hide	C26H22BrCl3N6O3	1
1	IC50 = 190 nM Bioactivity Info	TI LI LO TS
CP0861119 Compound Info	N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-2-[3-(3-methoxy-phenyl)-ureido]-N-methyl-acetamide hydrochloride Show/Hide	C26H25BrCl3N5O4	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0463789 Compound Info	N-[2-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichloro-N-methylanilino]-2-oxoethyl]hexanamide Show/Hide	C24H27BrCl2N4O3	1
1	IC50 = 240 nM Bioactivity Info	TI LI LO TS
CP0885625 Compound Info	N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-(3-p-tolyl-ureido)-acetamide hydrochloride Show/Hide	C26H25BrCl3N5O3	1
1	IC50 = 260 nM Bioactivity Info	TI LI LO TS
CP0535264 Compound Info	N-[2-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichloro-N-methylanilino]-2-oxoethyl]-3-phenylpropanamide Show/Hide	C27H25BrCl2N4O3	1
1	IC50 = 350 nM Bioactivity Info	TI LI LO TS
CP0445309 Compound Info	N-[2-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichloro-N-methylanilino]-2-oxoethyl]-4-phenylbutanamide Show/Hide	C28H27BrCl2N4O3	1
1	IC50 = 480 nM Bioactivity Info	TI LI LO TS
CP0374222 Compound Info	N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-N-methyl-2-[(2-phenoxyacetyl)amino]acetamide Show/Hide	C26H23BrCl2N4O4	1
1	IC50 = 510 nM Bioactivity Info	TI LI LO TS
CP0410477 Compound Info	2-(3-Benzoyl-ureido)-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide Show/Hide	C26H22BrCl2N5O4	1
1	IC50 = 510 nM Bioactivity Info	TI LI LO TS
CP0885968 Compound Info	2-(3-Benzyl-ureido)-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide hydrochloride Show/Hide	C26H25BrCl3N5O3	1
1	IC50 = 570 nM Bioactivity Info	TI LI LO TS
CP0454516 Compound Info	N-[2-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichloro-N-methylanilino]-2-oxoethyl]butanamide Show/Hide	C22H23BrCl2N4O3	1
1	IC50 = 610 nM Bioactivity Info	TI LI LO TS
CP0885535 Compound Info	N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-2-phenyl-acetamide hydrochloride Show/Hide	C26H24BrCl3N4O3	1
1	IC50 = 670 nM Bioactivity Info	TI LI LO TS
CP0429345 Compound Info	N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-2-[[2-(dimethylamino)acetyl]amino]-N-methylacetamide Show/Hide	C22H24BrCl2N5O3	1
1	IC50 = 830 nM Bioactivity Info	TI LI LO TS
CP0494786 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-benzooxazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide Show/Hide	C29H26Cl2N4O5	1
1	IC50 = 860 nM Bioactivity Info	TI LI LO TS
CP0891122 Compound Info	N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-2-[3-(3-chloro-phenyl)-ureido]-N-methyl-acetamide hydrochloride Show/Hide	C25H22BrCl4N5O3	1
1	IC50 = 1900 nM Bioactivity Info	TI LI LO TS
CP0511366 Compound Info	N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-2-(ethylcarbamoylamino)-N-methylacetamide Show/Hide	C21H22BrCl2N5O3	1
1	IC50 = 3000 nM Bioactivity Info	TI LI LO TS
CP0511276 Compound Info	4-((E)-2-{[({2,4-Dichloro-3-[2-(2,5-dimethyl-pyrrol-1-yl)-pyridin-3-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide Show/Hide	C32H31Cl2N5O4	1
1	IC50 = 3500 nM Bioactivity Info	TI LI LO TS
CP0920729 Compound Info	2-Acetylamino-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide hydrochloride Show/Hide	C20H20BrCl3N4O3	1
1	IC50 = 4100 nM Bioactivity Info	TI LI LO TS
CP0383199 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide Show/Hide	C30H27Cl2N5O4	1
1	IC50 = 4300 nM Bioactivity Info	TI LI LO TS
CP0410512 Compound Info	3-[3-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-ureido]-benzoic acid Show/Hide	C26H22BrCl2N5O5	1
1	IC50 = 5200 nM Bioactivity Info	TI LI LO TS
CP0377942 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(6-methyl-pyridin-2-ylmethoxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide Show/Hide	C28H28Cl2N4O4	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0410682 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(3-methyl-isoquinolin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide Show/Hide	C31H28Cl2N4O4	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0521181 Compound Info	4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-7-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide Show/Hide	C31H28Cl2N4O4	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0394067 Compound Info	2-[3-(3-Amino-phenyl)-ureido]-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide Show/Hide	C25H23BrCl2N6O3	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000064 , Chem-1

Cell Line Info

Cell Line ID: CL000011 , CHO

Cell Line Info

Cell Line ID: CL000389 , CHO-DXB11

Cell Line Info

Cell Line ID: CL000026 , CHO-K1

Cell Line Info

Cell Line ID: CL000053 , COS-7

Cell Line Info

Cell Line ID: CL000006 , HEK293

Cell Line Info

Cell Line ID: CL000837 , HF1-5

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0256063 Compound Info	(E)-N-[2-[2,4-dichloro-N-methyl-3-[[2-methyl-4-(pyridin-2-ylmethoxy)quinolin-8-yl]oxymethyl]anilino]-2-oxoethyl]-3-[6-[(E)-2-pyridin-4-ylethenyl]pyridin-3-yl]prop-2-enamide Show/Hide	C41H34Cl2N6O4	1
1	IC50 = 0.36 nM
CP0304790 Compound Info	4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide Show/Hide	C37H33Cl2N5O5	1
1	IC50 = 0.41 nM
CP0335342 Compound Info	(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichloro-3-(2-methoxy-1-pyridin-2-ylmethyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide Show/Hide	C34H31Cl2N7O5	1
1	IC50 = 0.69 nM
CP0128813 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,4R)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid Show/Hide	C60H87N19O13	3
1	IC50 = 7 nM
2	IC50 = 10 nM
3	IC50 = 14 nM
CP0309352 Compound Info	8-[3-chloro-5-(thiazol-2-ylsulfanyl)-pyridin-4-ylmethoxy]-2-methyl-4-(2-methyl-2Hpyrazol-3-yl)-quinoline Show/Hide	C23H18ClN5OS2	1
1	IC50 = 470 nM
CP0299612 Compound Info	(BK) H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH Show/Hide	C50H73N15O11	1
1	Ki = 0.11 nM

Clinical Information about the Protein

Target 1 ( B2 bradykinin receptor (BDKRB2) )

Target Type	Successful Target
Disease	5 Target-related Diseases				5
1	Hereditary angioedema [ICD-11: 4A00.14]
2	Osteoarthritis [ICD-11: FA00-FA05]
3	Brain cancer [ICD-11: 2A00]
4	Rhinitis [ICD-11: FA20]
5	Pain [ICD-11: MG30-MG3Z]
Approved Drug(s)	1 Approved Drug				1
1	Icatibant	Drug Info	Approved	Hereditary angioedema
Clinical Trial Drug(s)	1 Clinical Trial Drug				1
1	Fasitibant chloride	Drug Info	Phase 2	Osteoarthritis
Discontinued Drug(s)	3 Discontinued Drugs				3
1	Labradimil	Drug Info	Discontinued in Phase 2	Brain cancer
2	NPC-567	Drug Info	Discontinued in Phase 2	Rhinitis
3	JSM-10292	Drug Info	Terminated	Pain

Similar Protein(s) and Bioactivity Statistics

50% Identity

Protein ID	Protein Name	Protein Organism
PT07055	B2 bradykinin receptor	Rattus norvegicus, Rat	Protein Info

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han