General Information of the Cell Line
Cell Line ID
CL000064
Cell Line Name
Chem-1
Synonyms
ChemiSCREEN Chem-1
Wild-type control Chem-1 cell line
ChemiSCREEN Chem-1 parental cell line
Category
Undefined cell line type
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_L474
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02392, B2 bradykinin receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0299612
 Compound Info 
(BK) H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH
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C50H73N15O11
  2
1
IC50 = 1.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 1.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01021, C-C chemokine receptor type 2
 Protein Info 
Protein ID: PT01508, C-C chemokine receptor type 4
 Protein Info 
Protein ID: PT04523, C-C chemokine receptor type 5
 Protein Info 
Protein ID: PT03815, C-C chemokine receptor type 6
 Protein Info 
Protein ID: PT03433, C-X-C chemokine receptor type 3
 Protein Info 
Protein ID: PT02059, C-X-C chemokine receptor type 4
 Protein Info 
Protein ID: PT01298, Cannabinoid receptor 1
 Protein Info 
Protein ID: PT01200, Delta-type opioid receptor
 Protein Info 
Protein ID: PT03925, Lysophosphatidic acid receptor 1
 Protein Info 
Protein ID: PT02824, Lysophosphatidic acid receptor 3
 Protein Info 
Protein ID: PT01748, Metabotropic glutamate receptor 2
 Protein Info 
Protein ID: PT01054, Prostaglandin D2 receptor
 Protein Info 
Protein ID: PT01205, Prostaglandin E2 receptor EP1 subtype
 Protein Info 
Protein ID: PT00948, Prostaglandin E2 receptor EP2 subtype
 Protein Info 
Protein ID: PT01367, Prostaglandin E2 receptor EP3 subtype
 Protein Info 
Protein ID: PT01534, Prostaglandin E2 receptor EP4 subtype
 Protein Info 
Protein ID: PT01823, Prostaglandin F2-alpha receptor
 Protein Info 
Protein ID: PT01688, Sphingosine 1-phosphate receptor 1
 Protein Info 
Protein ID: PT01837, Sphingosine 1-phosphate receptor 2
 Protein Info 
Protein ID: PT01838, Sphingosine 1-phosphate receptor 3
 Protein Info 
Protein ID: PT01779, Sphingosine 1-phosphate receptor 4
 Protein Info 
Protein ID: PT01780, Sphingosine 1-phosphate receptor 5
 Protein Info 
Protein ID: PT06274, Succinate receptor 1
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0099464
 Compound Info 
N'-[[(2R)-4-(benzenesulfonyl)piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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 C24H35N5O2S  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0141162
 Compound Info 
[(3R)-3-[[4-aminobutyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]methyl]piperazin-1-yl]-phenylmethanone
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 C25H35N5O  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0406572
 Compound Info 
N'-[[(2S)-4-(4-chlorophenyl)sulfonylpiperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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 C24H34ClN5O2S  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0416320
 Compound Info 
[(3S)-3-[[4-aminobutyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]methyl]piperazin-1-yl]-phenylmethanone
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 C25H35N5O  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0425036
 Compound Info 
N'-[[(2S)-4-naphthalen-2-ylsulfonylpiperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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 C28H37N5O2S  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0450351
 Compound Info 
N'-[[(2R)-4-benzylpiperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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 C25H37N5  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0528841
 Compound Info 
N'-[[(2S)-piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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 C18H31N5  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0559064
 Compound Info 
N'-[[(2S)-4-(1-benzothiophen-2-ylsulfonyl)piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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 C26H35N5O2S2  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0563754
 Compound Info 
N'-[[(2S)-4-(benzenesulfonyl)piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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 C24H35N5O2S  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line