| Compound ID |
Compound Name |
Compound Formula |
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CP0489179
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N-(pyridin-2-ylmethyl)-N'-[[(3R)-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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C29H37N5
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
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CP0406572
|
N'-[[(2S)-4-(4-chlorophenyl)sulfonylpiperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C24H34ClN5O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
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CP0416320
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[(3S)-3-[[4-aminobutyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]methyl]piperazin-1-yl]-phenylmethanone
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|
C25H35N5O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
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CP0563754
|
N'-[[(2S)-4-(benzenesulfonyl)piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C24H35N5O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
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CP0070322
|
N'-[[(3R)-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C23H32N4
|
2
|
| 1 |
IC50 = 3 nM
|
|
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| 2 |
IC50 = 120 nM
|
|
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CP0484544
|
4-[[(3R)-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]butylurea
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|
C24H33N5O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
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CP0471105
|
N-[4-[[(3R)-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]butyl]acetamide
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|
C25H34N4O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
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CP0141162
|
[(3R)-3-[[4-aminobutyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]methyl]piperazin-1-yl]-phenylmethanone
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|
C25H35N5O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
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CP0445507
|
N-propan-2-yl-N'-[[(3R)-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C26H38N4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
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CP0069850
|
(6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate
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|
C21H34N4S2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
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CP0466954
|
N,N-dimethyl-N'-[[(3R)-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C25H36N4
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0444193
|
(6,6-dimethyl-5H-imidazo[2,1-b][1,3]thiazol-3-yl)methyl N'-[4-[[[2-[2-[6-[[2-[2-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]hexylamino]-2-oxoethoxy]acetyl]amino]methyl]cyclohexyl]-N-cyclohexylcarbamimidothioate
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|
C56H83N9O9S2
|
1
|
| 1 |
IC50 = 17.2 nM
|
|
|
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CP0416321
|
benzyl (3S)-3-[[4-aminobutyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]methyl]piperazine-1-carboxylate
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|
C26H37N5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
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CP0099464
|
N'-[[(2R)-4-(benzenesulfonyl)piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C24H35N5O2S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
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CP0431549
|
[(3R)-3-[[4-aminobutyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]methyl]piperazin-1-yl]-(furan-2-yl)methanone
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|
C23H33N5O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
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CP0387864
|
N'-[[(3R)-2-methyl-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C24H34N4
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
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CP0559064
|
N'-[[(2S)-4-(1-benzothiophen-2-ylsulfonyl)piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C26H35N5O2S2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
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CP0444196
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N'-[[(3R)-2-(pyridin-2-ylmethyl)-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
Show/Hide
|
C29H37N5
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
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CP0425036
|
N'-[[(2S)-4-naphthalen-2-ylsulfonylpiperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C28H37N5O2S
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
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CP0443356
|
N'-[(4-phenylpiperazin-2-yl)methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C24H35N5
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
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CP0387771
|
N'-[[(3R)-2-propan-2-yl-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
Show/Hide
|
C26H38N4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
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CP0387865
|
1,1-dimethyl-3-[4-[[(3R)-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]butyl]urea
Show/Hide
|
C26H37N5O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
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CP0125301
|
N'-[[(2S)-4-benzylpiperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C25H37N5
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
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CP0450351
|
N'-[[(2R)-4-benzylpiperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
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|
C25H37N5
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
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CP0428477
|
N'-[[(2R)-piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
Show/Hide
|
C18H31N5
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
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CP0524752
|
N'-[[(3R)-2-(pyridin-3-ylmethyl)-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
Show/Hide
|
C29H37N5
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
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CP0387863
|
N'-[[(3R)-2-(1,3-oxazol-4-ylmethyl)-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
Show/Hide
|
C27H35N5O
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
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CP0392740
|
2-[(3R)-3-[[4-aminobutyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-1-morpholin-4-ylethanone
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|
C29H41N5O2
|
1
|
| 1 |
IC50 = 570 nM
|
|
|
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CP0432257
|
N'-[[(3R)-2-(pyridin-4-ylmethyl)-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
Show/Hide
|
C29H37N5
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
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CP0528841
|
N'-[[(2S)-piperazin-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
Show/Hide
|
C18H31N5
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
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CP0511994
|
(6,6-dimethyl-5H-imidazo[2,1-b][1,3]thiazol-3-yl)methyl N'-[4-[[[2-[2-[4-[[2-[2-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]butylamino]-2-oxoethoxy]acetyl]amino]methyl]cyclohexyl]carbamimidothioate
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|
C48H69N9O9S2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
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CP0406573
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(3S)-3-[[4-aminobutyl-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]methyl]-N-phenylpiperazine-1-carboxamide
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|
C25H36N6O
|
1
|
| 1 |
IC50 = 21000 nM
|
|
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CP0564856
|
(6,6-dimethyl-5H-imidazo[2,1-b][1,3]thiazol-3-yl)methyl N-cyclohexyl-N'-[4-[[[2-[2-[4-[[2-[2-(methylamino)-2-oxoethoxy]acetyl]amino]butylamino]-2-oxoethoxy]acetyl]amino]methyl]cyclohexyl]carbamimidothioate
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|
C35H58N8O6S2
|
1
|
| 1 |
IC50 = 69000 nM
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