Brief Information of the Cell Line and Protein
Cell Line ID: CL000064 , Chem-1
 Cell Line Info 
Synonyms
ChemiSCREEN Chem-1
Wild-type control Chem-1 cell line
ChemiSCREEN Chem-1 parental cell line
Category Undefined cell line type
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_L474
Protein ID: PT00948 , Prostaglandin E2 receptor EP2 subtype
 Protein Info 
Gene Name PTGER2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P43116
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000064
 Cell Line Info 
 Protein ID: PT00948
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0452225
 Compound Info 
(E)-3-{2-[(E)-3-(4-Benzyloxy-3-methoxy-phenyl)-propenyl]-phenyl}-acrylic acid; compound with (E)-3-{2-[(E)-3-(4-benzyloxy-3-methoxy-phenyl)-allyl]-phenyl}-acrylic acid
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C26H24O4
  1
1
Ki = 1729 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0179414
 Compound Info 
3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-enyl)phenyl)-N-(thiophen-2-ylsulfonyl)acrylamide
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C30H27NO5S2
  1
1
Ki = 2415 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0857864
 Compound Info 
1-(2-(4-((E)-3-(2-((E)-2-Carboxyvinyl)phenyl)allyl)-2-methoxyphenoxy)ethyl)-4-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-dienyl)-2,6-dimethylpyridinium boron tetrafluoride
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C40H43BF4N2O4
  1
1
Ki = 2943 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0397467
 Compound Info 
(E)-3-[2-[(E)-3-[4-[2-(1-cyanoisoindol-2-yl)ethoxy]-3-methoxyphenyl]prop-1-enyl]phenyl]prop-2-enoic acid
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C30H26N2O4
  1
1
Ki = 4264 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0058712
 Compound Info 
N-[5-(2,6-dichlorophenyl)-1,3,4-thiadiazol-2-yl]-4-ethyl-2,3-dihydro-1,4-benzoxazine-6-carboxamide
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C19H16Cl2N4O2S
  1
1
Ki > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380092
 Compound Info 
N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-4-ethyl-2,3-dihydro-1,4-benzoxazine-6-carboxamide
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C16H18N4O2S
  1
1
Ki > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0314860
 Compound Info 
(E)-3-[2-[(E)-3-[4-[2-(1-cyanoisoindol-2-yl)ethoxy]-3-methoxyphenyl]prop-1-enyl]phenyl]-N-thiophen-2-ylsulfonylprop-2-enamide
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C34H29N3O5S2
  1
1
Ki = 10810 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS