General Information of the Cell Line
Cell Line ID
CL000767
Cell Line Name
HMEC-1
Synonyms
Hmec-1
HMEC1
CDC/EU.HMEC-1
Human Microvascular Endothelial Cell line-1
Category
Transformed cell line
Organism
Homo sapiens (Human)
Tissue Information
skin
Disease None
Table of Molecular Bioactivities Related to the Cell Line
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0034824
4-((1H-benzo[d]imidazol-2-ylthio)methyl)-N-(2-aminophenyl)benzamide
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C21H18N4OS  1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
CP0103411
N-(2-aminophenyl)-4-[[(6-methoxy-1,3-benzothiazol-2-yl)amino]methyl]benzamide
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C22H20N4O2S  1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0155652
N-(2-aminophenyl)-4-(1,3-benzothiazol-2-ylsulfanylmethyl)benzamide
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C21H17N3OS2  1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0200998
N-(2-aminophenyl)-4-[(2,4-dioxo-1H-quinazolin-3-yl)methyl]benzamide
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C22H18N4O3  1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0336829
4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-aminophenyl)benzamide
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C21H19N5O  1
1
IC50 = 27000 nM
   TI
   LI
   LO
   TS
CP0344156
N-(2-aminophenyl)-4-[[(5-chloro-1,3-benzoxazol-2-yl)amino]methyl]benzamide
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C21H17ClN4O2  1
1
IC50 = 17000 nM
   TI
   LI
   LO
   TS
CP0445430
N-(2-aminophenyl)-4-[(4-oxochromen-3-yl)methyl]benzamide
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C23H18N2O3  1
1
IC50 = 9000 nM
   TI
   LI
   LO
   TS
CP0458267
6,7-bis[(4-nitrophenyl)methoxy]spiro[chromene-2,4'-oxane]
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C27H24N2O8  2
1
IC50 = 79530 nM
   TI
   LI
   LO
   TS
2
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0463958
N-(2-aminophenyl)-4-[(2-methyl-4-oxoquinazolin-3-yl)methyl]benzamide
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C23H20N4O2  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0485794
N-(2-aminophenyl)-4-[(3-oxo-1H-isoindol-2-yl)methyl]benzamide
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C22H19N3O2  1
1
IC50 = 37000 nM
   TI
   LI
   LO
   TS
CP0485795
N-(2-aminophenyl)-4-[(3-oxo-1,2-dihydroinden-2-yl)methyl]benzamide
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C23H20N2O2  1
1
IC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0510831
N-(2-aminophenyl)-4-[(1,3-dioxoisoindol-2-yl)methyl]benzamide
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C22H17N3O3  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0515171
N-(2-aminophenyl)-4-[(1-ethyl-2,4-dioxothieno[3,2-d]pyrimidin-3-yl)methyl]benzamide
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C22H20N4O3S  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0515172
N-(2-aminophenyl)-4-[(4-oxoquinazolin-3-yl)methyl]benzamide
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C22H18N4O2  1
1
IC50 = 28000 nM
   TI
   LI
   LO
   TS
CP0522235
N-(2-aminophenyl)-4-[(4-oxothieno[3,2-d]pyrimidin-3-yl)methyl]benzamide
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C20H16N4O2S  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0552272
N-(2-aminophenyl)-4-[(4-oxo-2,3-dihydrochromen-3-yl)methyl]benzamide
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C23H20N2O3  1
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0552273
N-(2-aminophenyl)-4-[(2,4-dioxo-1H-thieno[3,2-d]pyrimidin-3-yl)methyl]benzamide
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C20H16N4O3S  1
1
IC50 = 29000 nM
   TI
   LI
   LO
   TS
CP0634648
N-((R)-Cyclopropyl(pyridin-2-yl)methyl)-3-(4-((endo)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)phenyl)-1H-indazole-5-carboxamide
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C30H31N5O2  1
1
GI50 > 30000 nM
   TI
   LI
   LO
   TS
CP0887412
4-[[[1-(2-Fluorophenyl)cyclopentyl]amino]methyl]-2-[(4-methylpiperazin-1-yl)methyl]phenol
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C24H32FN3O  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (skin)
Cell Line Name Organism Disease
A-375 Homo sapiens (Human) Amelanotic melanoma
A375-P Homo sapiens (Human) Amelanotic melanoma
A375-SM Homo sapiens (Human) Amelanotic melanoma
SK-MEL-28 Homo sapiens (Human) Cutaneous melanoma
EBC-1 Homo sapiens (Human) Lung squamous cell carcinoma
WM115 Homo sapiens (Human) Melanoma
WM266-4 Homo sapiens (Human) Melanoma
G-361 Homo sapiens (Human) Melanoma
UACC-62 Homo sapiens (Human) Melanoma
SK-MEL-2 Homo sapiens (Human) Melanoma
Mt2-4 Homo sapiens (Human) Mitochondrial diabetes
NMIi005-A Homo sapiens (Human) Schizophrenia
A-431 Homo sapiens (Human) Skin squamous cell carcinoma
FF Mesocricetus auratus (Golden hamster) Hamster melanoma
B16-F10 Mus musculus (Mouse) Mouse melanoma
B16 Mus musculus (Mouse) Mouse melanoma
B16-BL6 Mus musculus (Mouse) Mouse melanoma
B16-F1 Mus musculus (Mouse) Mouse melanoma
B16-F0 Mus musculus (Mouse) Mouse melanoma
HaCaT Homo sapiens (Human) -
HFF Homo sapiens (Human) -
S12 [Human keratinocyte] Homo sapiens (Human) -
Malme-3 Homo sapiens (Human) -
BJ [Human fibroblast] Homo sapiens (Human) -
297L1 Homo sapiens (Human) -
HaCaT-ARE-Luc Homo sapiens (Human) -
Melan-a Mus musculus (Mouse) -
JB6 Cl 41-5a Mus musculus (Mouse) -