General Information of the Cell Line
Cell Line ID
CL000087
Cell Line Name
B16
Synonyms
B-16
B16 melanoma
B16 subline B78
B78
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_F936
Tissue Information
Skin
Disease
Mouse melanoma (NCIt: C21790)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03388, Indoleamine 2,3-dioxygenase 1
Compound ID Compound Name Compound Formula
CP0236732
4-amino-N-(3-chloro-4-fluorophenyl)-N&#8242;-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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C9H7ClFN5O2
 2
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
2
IC50 = 1000 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0381177
N-hydroxy-4-[[3-methoxypropyl(phenylcarbamoyl)amino]methyl]benzamide
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C19H23N3O4  1
1
GI50 = 22200 nM
   TI
   LI
   LO
   TS
CP0451560
N-hydroxy-4-[[2-(4-hydroxyphenyl)ethyl-[(2-methoxyphenyl)carbamoyl]amino]methyl]benzamide
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C24H25N3O5  1
1
GI50 = 18400 nM
   TI
   LI
   LO
   TS
CP0453542
N-hydroxy-4-[[[3-methoxypropyl(phenyl)carbamoyl]amino]methyl]benzamide
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C19H23N3O4  1
1
GI50 > 100000 nM
   TI
   LI
   LO
   TS
CP0453543
N-hydroxy-4-[[3-hydroxypropyl-[(2-methoxyphenyl)carbamoyl]amino]methyl]benzamide
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C19H23N3O5  1
1
GI50 > 100000 nM
   TI
   LI
   LO
   TS
CP0479527
N-hydroxy-4-[[2-methoxyethyl(phenylcarbamoyl)amino]methyl]benzamide
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C18H21N3O4  1
1
GI50 = 19100 nM
   TI
   LI
   LO
   TS
CP0541091
4-[[3-(dimethylamino)propyl-[(2-methoxyphenyl)carbamoyl]amino]methyl]-N-hydroxybenzamide
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C21H28N4O4  1
1
GI50 = 75300 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Skin)
Cell Line Name Organism Disease
A-375 Homo sapiens (Human) Amelanotic melanoma
A375-P Homo sapiens (Human) Amelanotic melanoma
A375-SM Homo sapiens (Human) Amelanotic melanoma
SK-MEL-28 Homo sapiens (Human) Cutaneous melanoma
EBC-1 Homo sapiens (Human) Lung squamous cell carcinoma
WM115 Homo sapiens (Human) Melanoma
WM266-4 Homo sapiens (Human) Melanoma
G-361 Homo sapiens (Human) Melanoma
UACC-62 Homo sapiens (Human) Melanoma
SK-MEL-2 Homo sapiens (Human) Melanoma
Mt2-4 Homo sapiens (Human) Mitochondrial diabetes
NMIi005-A Homo sapiens (Human) Schizophrenia
A-431 Homo sapiens (Human) Skin squamous cell carcinoma
FF Mesocricetus auratus (Golden hamster) Hamster melanoma
B16-F10 Mus musculus (Mouse) Mouse melanoma
B16-BL6 Mus musculus (Mouse) Mouse melanoma
B16-F1 Mus musculus (Mouse) Mouse melanoma
B16-F0 Mus musculus (Mouse) Mouse melanoma
HaCaT Homo sapiens (Human) -
HFF Homo sapiens (Human) -
S12 [Human keratinocyte] Homo sapiens (Human) -
Malme-3 Homo sapiens (Human) -
BJ [Human fibroblast] Homo sapiens (Human) -
HMEC-1 Homo sapiens (Human) -
297L1 Homo sapiens (Human) -
HaCaT-ARE-Luc Homo sapiens (Human) -
Melan-a Mus musculus (Mouse) -
JB6 Cl 41-5a Mus musculus (Mouse) -