Brief Information of the Compound and Protein
Compound Name
4-amino-N-(3-chloro-4-fluorophenyl)-N′-hydroxy-1,2,5-oxadiazole-3-carboximidamide
    Show/Hide
PubChem ID
CID: 135424953
SID: 17430900
Canonical SMILES
Nc1nonc1C(Nc1ccc(F)c(Cl)c1)=NO
    Show/Hide
Compound Formula C9H7ClFN5O2
Compound Structure
Protein Name
Indoleamine 2,3-dioxygenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28776
Gene Name
IDO1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000087 B16 Mus musculus (Mouse)  2
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
2
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CL000784 P815B Mus musculus (Mouse)  1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS