General Information of the Cell Line
Cell Line ID
CL000038
Cell Line Name
B16-F10
Synonyms
B16/F10
B16 F10
B16F10
B16 melanoma F10
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0159
Tissue Information
Skin
Disease
Mouse melanoma (NCIt: C21790)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01014, Cysteine protease CPP32
 Protein Info 
Compound ID Compound Name Compound Formula
CP0036823
 Compound Info 
(-)-etoposide
   Show/Hide
C29H32O13
  1
1
IC50 > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01440, Melanocyte-stimulating hormone receptor
 Protein Info 
Protein ID: PT04537, Monoglyceride lipase
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0069866
 Compound Info 
CAS_74103-07-4
   Show/Hide
 C15H13NO3  1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0078293
 Compound Info 
N-[(9R)-4-(3H-imidazo[4,5-c]pyridin-2-yl)-9H-fluoren-9-yl]-1H-pyrrolo[2,3-b]pyridine-4-carboxamide
   Show/Hide
 C27H18N6O  1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CP0115097
 Compound Info 
(E)-1-(4-chloropiperidin-1-yl)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-en-1-one
   Show/Hide
 C25H28ClNO4  1
1
IC50 = 4690 nM
   TI
   LI
   LO
   TS
CP0130370
 Compound Info 
(E)-N-(2-chloroethyl)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
   Show/Hide
 C22H24ClNO4  1
1
IC50 = 3450 nM
   TI
   LI
   LO
   TS
CP0130372
 Compound Info 
(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(2-methylpiperidin-1-yl)prop-2-en-1-one
   Show/Hide
 C26H31NO4  1
1
IC50 = 7660 nM
   TI
   LI
   LO
   TS
CP0169377
 Compound Info 
(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dimethylprop-2-enamide
   Show/Hide
 C22H25NO4  1
1
IC50 = 5780 nM
   TI
   LI
   LO
   TS
CP0252072
 Compound Info 
(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-bis(prop-2-enyl)prop-2-enamide
   Show/Hide
 C26H29NO4  1
1
IC50 = 8180 nM
   TI
   LI
   LO
   TS
CP0252074
 Compound Info 
(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-octylprop-2-enamide
   Show/Hide
 C28H37NO4  1
1
IC50 = 8060 nM
   TI
   LI
   LO
   TS
CP0259374
 Compound Info 
(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dipropylprop-2-enamide
   Show/Hide
 C26H33NO4  1
1
IC50 = 5980 nM
   TI
   LI
   LO
   TS
CP0259375
 Compound Info 
(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-prop-2-ynylprop-2-enamide
   Show/Hide
 C23H23NO4  1
1
IC50 = 8280 nM
   TI
   LI
   LO
   TS
CP0283447
 Compound Info 
(E)-N-cyclopropyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
   Show/Hide
 C23H25NO4  1
1
IC50 = 10160 nM
   TI
   LI
   LO
   TS
CP0283448
 Compound Info 
(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-hexylprop-2-enamide
   Show/Hide
 C26H33NO4  1
1
IC50 = 7180 nM
   TI
   LI
   LO
   TS
CP0297599
 Compound Info 
2-benzylsulfanyl-5-(2-methylphenyl)-1,3,4-oxadiazole
   Show/Hide
 C16H14N2OS  1
1
IC50 = 19900 nM
   TI
   LI
   LO
   TS
CP0306912
 Compound Info 
4-N-(3-bromophenyl)-6-N-(3,4-dihydro-2H-1,5-benzodioxepin-7-ylmethyl)quinazoline-4,6-diamine
   Show/Hide
 C24H21BrN4O2  1
1
IC50 = 4168.761522 nM
   TI
   LI
   LO
   TS
CP0334152
 Compound Info 
(E)-N-(3-chloropropyl)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
   Show/Hide
 C23H26ClNO4  1
1
IC50 = 2780 nM
   TI
   LI
   LO
   TS
CP0334155
 Compound Info 
(E)-N-tert-butyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
   Show/Hide
 C24H29NO4  1
1
IC50 = 7980 nM
   TI
   LI
   LO
   TS
CP0363604
 Compound Info 
(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-pyrrolidin-1-ylprop-2-en-1-one
   Show/Hide
 C24H27NO4  1
1
IC50 = 9280 nM
   TI
   LI
   LO
   TS
CP0396709
 Compound Info 
(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(3-methoxyphenyl)prop-2-enamide
   Show/Hide
 C24H19BrN4O2  1
1
IC50 = 1830.230357 nM
   TI
   LI
   LO
   TS
CP0425415
 Compound Info 
(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-(3-methoxyphenyl)prop-2-enamide
   Show/Hide
 C24H19ClN4O2  1
1
IC50 = 2436.760269 nM
   TI
   LI
   LO
   TS
CP0431327
 Compound Info 
2-benzylsulfanyl-5-(2-methoxyphenyl)-1,3,4-oxadiazole
   Show/Hide
 C16H14N2O2S  1
1
IC50 = 19300 nM
   TI
   LI
   LO
   TS
CP0467518
 Compound Info 
2-benzylsulfanyl-5-(2-ethoxyphenyl)-1,3,4-oxadiazole
   Show/Hide
 C17H16N2O2S  1
1
IC50 = 17900 nM
   TI
   LI
   LO
   TS
CP0468346
 Compound Info 
(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(2-bromophenyl)prop-2-enamide
   Show/Hide
 C23H16Br2N4O  1
1
IC50 = 1754.988364 nM
   TI
   LI
   LO
   TS
CP0502534
 Compound Info 
(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-(4-nitrophenyl)prop-2-enamide
   Show/Hide
 C23H16ClN5O3  1
1
IC50 = 4597.752708 nM
   TI
   LI
   LO
   TS
CP0509049
 Compound Info 
(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-methoxyphenyl)prop-2-enamide
   Show/Hide
 C24H19BrN4O2  1
1
IC50 = 2608.604186 nM
   TI
   LI
   LO
   TS
CP0510293
 Compound Info 
[1-(2-methoxyphenyl)triazol-4-yl]methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate
   Show/Hide
 C25H22N4O4  1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0523766
 Compound Info 
2-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)-5-methylphenol
   Show/Hide
 C16H14N2O2S  1
1
IC50 = 9000 nM
   TI
   LI
   LO
   TS
CP0523767
 Compound Info 
2-benzylsulfanyl-5-(4-tert-butylphenyl)-1,3,4-oxadiazole
   Show/Hide
 C19H20N2OS  1
1
IC50 = 9200 nM
   TI
   LI
   LO
   TS
CP0523768
 Compound Info 
2-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)aniline
   Show/Hide
 C15H13N3OS  1
1
IC50 = 10300 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Skin)
Cell Line Name Organism Disease
A-375
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
A375-P
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
A375-SM
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
SK-MEL-28
 Cell Line Info 
Homo sapiens (Human) Cutaneous melanoma
EBC-1
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
WM115
 Cell Line Info 
Homo sapiens (Human) Melanoma
WM266-4
 Cell Line Info 
Homo sapiens (Human) Melanoma
G-361
 Cell Line Info 
Homo sapiens (Human) Melanoma
UACC-62
 Cell Line Info 
Homo sapiens (Human) Melanoma
SK-MEL-2
 Cell Line Info 
Homo sapiens (Human) Melanoma
Mt2-4
 Cell Line Info 
Homo sapiens (Human) Mitochondrial diabetes
NMIi005-A
 Cell Line Info 
Homo sapiens (Human) Schizophrenia
A-431
 Cell Line Info 
Homo sapiens (Human) Skin squamous cell carcinoma
FF
 Cell Line Info 
Mesocricetus auratus (Golden hamster) Hamster melanoma
B16
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-BL6
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-F1
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-F0
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
HaCaT
 Cell Line Info 
Homo sapiens (Human) -
HFF
 Cell Line Info 
Homo sapiens (Human) -
S12 [Human keratinocyte]
 Cell Line Info 
Homo sapiens (Human) -
Malme-3
 Cell Line Info 
Homo sapiens (Human) -
BJ [Human fibroblast]
 Cell Line Info 
Homo sapiens (Human) -
HMEC-1
 Cell Line Info 
Homo sapiens (Human) -
297L1
 Cell Line Info 
Homo sapiens (Human) -
HaCaT-ARE-Luc
 Cell Line Info 
Homo sapiens (Human) -
Melan-a
 Cell Line Info 
Mus musculus (Mouse) -
JB6 Cl 41-5a
 Cell Line Info 
Mus musculus (Mouse) -