General Information of the Cell Line
Cell Line ID
CL001000
Cell Line Name
NMIi005-A
Synonyms
SZ4
Category
Induced pluripotent stem cell
Organism
Homo sapiens (Human)
Tissue Information
Skin
Disease
Schizophrenia (NCIt: C3362)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00892, Tyrosine-protein kinase JAK3
 Protein Info 
Compound ID Compound Name Compound Formula
CP0002393
 Compound Info 
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
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C16H20N6O
  1
1
IC50 = 1210 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0756820
 Compound Info 
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
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C24H23N5O4
  1
1
IC50 = 1550 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0083241
 Compound Info 
US10399979, Compound 17a
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C22H23N3O3
  1
1
IC50 = 3720 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0230502
 Compound Info 
US10399979, Compound 17c
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C23H25N3O3
  1
1
IC50 = 18340 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0104423
 Compound Info 
US10399979, Compound 17d
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C24H27N3O3
  1
1
IC50 = 28860 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0104421
 Compound Info 
US10399979, Compound 17e
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C22H24N4O3
  1
1
IC50 = 61570 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0238761
 Compound Info 
US10399979, Compound 17b
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C23H25N3O3
  1
1
IC50 = 76900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Skin)
Cell Line Name Organism Disease
A-375
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
A375-P
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
A375-SM
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
SK-MEL-28
 Cell Line Info 
Homo sapiens (Human) Cutaneous melanoma
EBC-1
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
WM115
 Cell Line Info 
Homo sapiens (Human) Melanoma
WM266-4
 Cell Line Info 
Homo sapiens (Human) Melanoma
G-361
 Cell Line Info 
Homo sapiens (Human) Melanoma
UACC-62
 Cell Line Info 
Homo sapiens (Human) Melanoma
SK-MEL-2
 Cell Line Info 
Homo sapiens (Human) Melanoma
Mt2-4
 Cell Line Info 
Homo sapiens (Human) Mitochondrial diabetes
A-431
 Cell Line Info 
Homo sapiens (Human) Skin squamous cell carcinoma
FF
 Cell Line Info 
Mesocricetus auratus (Golden hamster) Hamster melanoma
B16-F10
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-BL6
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-F1
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-F0
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
HaCaT
 Cell Line Info 
Homo sapiens (Human) -
HFF
 Cell Line Info 
Homo sapiens (Human) -
S12 [Human keratinocyte]
 Cell Line Info 
Homo sapiens (Human) -
Malme-3
 Cell Line Info 
Homo sapiens (Human) -
BJ [Human fibroblast]
 Cell Line Info 
Homo sapiens (Human) -
HMEC-1
 Cell Line Info 
Homo sapiens (Human) -
297L1
 Cell Line Info 
Homo sapiens (Human) -
HaCaT-ARE-Luc
 Cell Line Info 
Homo sapiens (Human) -
Melan-a
 Cell Line Info 
Mus musculus (Mouse) -
JB6 Cl 41-5a
 Cell Line Info 
Mus musculus (Mouse) -