Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
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 PubChem ID
CID: 138585027
Canonical SMILES
COc1cc2c(=O)n([C@@H]3CCCN(C(=O)CC#N)C3)c3c4cc[nH]c4ncc3c2cc1OC
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Compound Formula C24H23N5O4
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P52333
Gene Name
JAK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001000 NMIi005-A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1550 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.55 nM