| Compound ID |
Compound Name |
Compound Formula |
|
CP0500250
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]-2-methylsulfanylphenyl]urea
Show/Hide
|
C29H29N7O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0176359
|
US8933228, 8
Show/Hide
|
C33H31N7O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0470680
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[2-methylsulfanyl-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C29H29N7O3S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0373062
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]-2-methylsulfanylphenyl]urea
Show/Hide
|
C30H31N7O3S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0522108
|
1-[4-[(2-amino-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]-3-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]urea
Show/Hide
|
C32H30N8O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0523858
|
1-[4-[(2-amino-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]-3-(5-tert-butyl-2-phenylpyrazol-3-yl)urea
Show/Hide
|
C31H28N8O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0086175
|
US8933228, 7
Show/Hide
|
C32H29N7O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0099352
|
US8933228, 5
Show/Hide
|
C31H27N7O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0116189
|
US8933228, 6
Show/Hide
|
C32H29N7O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0500249
|
1-[4-[(2-amino-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]-3-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]urea
Show/Hide
|
C28H27FN8O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0534644
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[2-fluoro-4-[(3-oxo-2,4-dihydro-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C28H28FN7O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0107942
|
US8933228, 1
Show/Hide
|
C31H29N7O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0374345
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C31H29N7O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0518750
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C28H26FN7O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0087000
|
US8933228, 3
Show/Hide
|
C32H31N7O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0374344
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C31H29N7O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0161401
|
2-(3,4-Methylenedioxyphenylamino)-6-(3-acetamidophenyl)-pyrazine
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|
C19H16N4O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0374336
|
US8933228, 2
Show/Hide
|
C30H27N7O3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0389726
|
1-[5-tert-butyl-2-(4-fluorophenyl)pyrazol-3-yl]-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C31H28FN7O3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0845385
|
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(1-methyl-2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea citrate
Show/Hide
|
C34H37N7O10
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0492862
|
1-[4-[(3-amino-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]-3-(5-tert-butyl-2-phenylpyrazol-3-yl)urea
Show/Hide
|
C31H28N8O3
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0470696
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[2-fluoro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C27H26FN7O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0508292
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C31H27N7O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0523857
|
1-[4-[(2-amino-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C25H16F4N6O3
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0504514
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(1,3-dimethyl-2-oxoimidazo[4,5-b]pyridin-7-yl)oxy-2-fluorophenyl]urea
Show/Hide
|
C29H30FN7O3
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0374338
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C28H29N7O3
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0508294
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[2-fluoro-4-[(2-sulfanylidene-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C27H26FN7O2S
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0389725
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[2-methylsulfanyl-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C28H29N7O3S
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0494261
|
1-[5-tert-butyl-2-(6-methylpyridin-3-yl)pyrazol-3-yl]-3-[2-fluoro-4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C27H27FN8O3
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0508290
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C26H17F4N5O3
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0508295
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[3-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C29H29N7O3
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0402315
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C32H31N7O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0494264
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)sulfanyl]phenyl]urea
Show/Hide
|
C26H25N7O2S
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0522109
|
1-[4-[(3-amino-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]-3-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]urea
Show/Hide
|
C28H27FN8O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0523856
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(2,3-dioxo-1,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]urea
Show/Hide
|
C28H26FN7O4
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0400013
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C28H29N7O3
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0502354
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C28H27N7O3
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0476476
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]-2-methylsulfanylphenyl]urea
Show/Hide
|
C23H17F4N5O3S
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0373981
|
1-(5-tert-butyl-2-pyridin-3-ylpyrazol-3-yl)-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C30H28N8O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0518752
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-methylsulfanyl-4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C28H27N7O3S
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0402313
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-(1,3-dimethyl-2-oxoimidazo[4,5-b]pyridin-7-yl)oxy-2-fluorophenyl]urea
Show/Hide
|
C28H28FN7O3
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0389728
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C27H27N7O3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0507511
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-fluoro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C26H24FN7O3
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0476481
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(3-methyl-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C32H29N7O3
|
1
|
| 1 |
IC50 = 141 nM
|
|
|
|
CP0507513
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C27H27N7O3
|
1
|
| 1 |
IC50 = 164 nM
|
|
|
|
CP0508293
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(3-methyl-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C33H31N7O3
|
1
|
| 1 |
IC50 = 176 nM
|
|
|
|
CP0477563
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-methylsulfanyl-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C22H15ClF3N5O3S
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
|
CP0374337
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(1,3-dimethyl-2-oxoimidazo[4,5-b]pyridin-7-yl)oxyphenyl]urea
Show/Hide
|
C29H31N7O3
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0508289
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[2-methylsulfanyl-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C22H15F4N5O3S
|
1
|
| 1 |
IC50 = 195 nM
|
|
|
|
CP0389727
|
1-[5-tert-butyl-2-(4-fluorophenyl)pyrazol-3-yl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C30H26FN7O3
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0036031
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C24H15F4N5O3
|
1
|
| 1 |
IC50 = 214 nM
|
|
|
|
CP0431431
|
1-(3-fluorophenyl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C23H16FN5O3
|
1
|
| 1 |
IC50 = 214 nM
|
|
|
|
CP0502355
|
1-[4-[(3-amino-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C25H16F4N6O3
|
1
|
| 1 |
IC50 = 229 nM
|
|
|
|
CP0429704
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)sulfanyl]phenyl]urea
Show/Hide
|
C27H27N7O2S
|
1
|
| 1 |
IC50 = 234 nM
|
|
|
|
CP0540415
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2-fluoronaphthalen-1-ol
Show/Hide
|
C28H25FN4O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0470666
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(2,3-dioxo-1,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]urea
Show/Hide
|
C27H24FN7O4
|
1
|
| 1 |
IC50 = 273 nM
|
|
|
|
CP0492863
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[3-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C28H27N7O3
|
1
|
| 1 |
IC50 = 274 nM
|
|
|
|
CP0497130
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[2-fluoro-4-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-8-yl)oxyphenyl]urea
Show/Hide
|
C32H33FN8O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0518753
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[3-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C27H25N7O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0504008
|
1-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C28H23F3N6O4
|
1
|
| 1 |
IC50 = 346 nM
|
|
|
|
CP0507515
|
1-[5-tert-butyl-2-(4-chlorophenyl)pyrazol-3-yl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C26H24ClN7O3
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0374027
|
1-(5-tert-butyl-2-methylpyrazol-3-yl)-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C26H27N7O3
|
1
|
| 1 |
IC50 = 383 nM
|
|
|
|
CP0373063
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-fluoro-4-[(3-methyl-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C28H26FN7O3
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0540416
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalen-1-ol
Show/Hide
|
C28H26N4O2
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0532667
|
1-[5-tert-butyl-2-(4-fluorophenyl)pyrazol-3-yl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C26H24FN7O3
|
1
|
| 1 |
IC50 = 411 nM
|
|
|
|
CP0507514
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C27H27N7O3
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0447615
|
1-(5-tert-butyl-2-methylpyrazol-3-yl)-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C26H27N7O3
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0174063
|
2-(3-Oxo-1,3-dihydroisobenzofuran-5-ylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C20H16N4O3
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0373061
|
1-[4-[(2,3-dioxo-1,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy]-2-methylsulfanylphenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H15F4N5O4S
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0510557
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C24H15ClF3N5O3
|
1
|
| 1 |
IC50 = 559 nM
|
|
|
|
CP0400401
|
6-[2-[4-(4-methylpiperazin-1-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C29H27N7
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0476473
|
1-[2-fluoro-4-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H14F5N5O3
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0545336
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(2,3-dioxo-1,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy]-2-methylsulfanylphenyl]urea
Show/Hide
|
C22H15ClF3N5O4S
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0388473
|
1-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C25H18F3N5O3
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0510344
|
1-[4-[(2,3-dioxo-1,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H12F5N5O4
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0397287
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-methylsulfanyl-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H15ClF3N5O3S
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0447616
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C26H25N7O3
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0523855
|
1-(5-tert-butyl-2-methylpyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C22H22FN7O3
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0476480
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C28H27N7O3
|
1
|
| 1 |
IC50 = 634 nM
|
|
|
|
CP0518751
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-fluoro-4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C27H24FN7O3
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0507811
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C21H12ClF4N5O3
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0381257
|
[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C25H23N5O2
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0398601
|
[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C28H30N6O2
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0373071
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-fluoro-4-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-8-yl]oxyphenyl]urea
Show/Hide
|
C32H34FN9O2
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0508296
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-fluoro-4-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-8-yl)oxyphenyl]urea
Show/Hide
|
C31H31FN8O3
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0504009
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C25H17ClF3N5O3
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0373068
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[3-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C28H27N7O3
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0508287
|
1-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H12F5N5O3
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0443522
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C25H17F4N5O3
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0374031
|
1-(5-tert-butyl-2-pyridin-3-ylpyrazol-3-yl)-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C26H26N8O3
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0917066
|
1-(3-Tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C28H28N6O3
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0402329
|
[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]-morpholin-4-ylmethanone
Show/Hide
|
C24H20N4O3
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0373069
|
3-tert-butyl-N-[3-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]benzamide
Show/Hide
|
C24H22N4O3
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0398708
|
[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]-piperazin-1-ylmethanone
Show/Hide
|
C24H21N5O2
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0387811
|
1-(3-tert-butylphenyl)-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C28H27N5O3
|
1
|
| 1 |
IC50 = 1060 nM
|
|
|
|
CP0039591
|
N-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]benzamide
Show/Hide
|
C27H25N5O3
|
1
|
| 1 |
IC50 = 1090 nM
|
|
|
|
CP0471629
|
2-[4-[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C28H26N6O
|
1
|
| 1 |
IC50 = 1090 nM
|
|
|
|
CP0538533
|
1-[5-tert-butyl-2-(2,4-difluorophenyl)pyrazol-3-yl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C26H23F2N7O3
|
1
|
| 1 |
IC50 = 1190 nM
|
|
|
|
CP0460038
|
2-chloro-6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalen-1-ol
Show/Hide
|
C28H25ClN4O2
|
1
|
| 1 |
IC50 = 1250 nM
|
|
|
|
CP0443523
|
1-[2-fluoro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[3-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H12F5N5O3
|
1
|
| 1 |
IC50 = 1290 nM
|
|
|
|
CP0043912
|
1-[2-methylsulfanyl-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H16F3N5O3S
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0387814
|
1-[2-chloro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[4-chloro-3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H12Cl2F3N5O3
|
1
|
| 1 |
IC50 = 1330 nM
|
|
|
|
CP0045760
|
1-(3-Tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C27H26N6O3
|
1
|
| 1 |
IC50 = 1330 nM
|
|
|
|
CP0374340
|
1-[5-tert-butyl-2-(4-fluorophenyl)pyrazol-3-yl]-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C27H26FN7O3
|
1
|
| 1 |
IC50 = 1360 nM
|
|
|
|
CP0161405
|
2-(3-Chlorophenylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C18H15ClN4O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0470688
|
3-tert-butyl-N-[3-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]benzamide
Show/Hide
|
C25H24N4O3
|
1
|
| 1 |
IC50 = 1430 nM
|
|
|
|
CP0505992
|
1-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]-3-[3-(trifluoromethylsulfanyl)phenyl]urea
Show/Hide
|
C25H18F3N5O3S
|
1
|
| 1 |
IC50 = 1460 nM
|
|
|
|
CP0383643
|
1-[4-[(2-amino-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H13F5N6O3
|
1
|
| 1 |
IC50 = 1550 nM
|
|
|
|
CP0505993
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-fluoro-4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H14ClF4N5O3
|
1
|
| 1 |
IC50 = 1570 nM
|
|
|
|
CP0373067
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[[2-(dimethylamino)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-2-fluorophenyl]urea
Show/Hide
|
C28H29FN8O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0470691
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[4-[3-(dimethylamino)pyrido[2,3-b]pyrazin-8-yl]oxy-2-fluorophenyl]urea
Show/Hide
|
C29H29FN8O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0523860
|
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[3-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C27H25N7O3
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0431432
|
1-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C24H16F3N5O3
|
1
|
| 1 |
IC50 = 1910 nM
|
|
|
|
CP0919063
|
1-(3-Tert-butyl-1-(4-fluorophenyl)-1H-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C27H25FN6O3
|
1
|
| 1 |
IC50 = 1960 nM
|
|
|
|
CP0400015
|
1-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-(2-phenyl-5-propan-2-ylpyrazol-3-yl)urea
Show/Hide
|
C25H23N7O3
|
1
|
| 1 |
IC50 = 1970 nM
|
|
|
|
CP0505994
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C25H17F4N5O3
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0384790
|
N,N-dimethyl-2-[4-[4-[4-(4-methyl-1H-pyrazol-5-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
|
C28H28N6O
|
1
|
| 1 |
IC50 = 2020 nM
|
|
|
|
CP0887310
|
N-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)benzamide
Show/Hide
|
C28H27N5O3
|
1
|
| 1 |
IC50 = 2050 nM
|
|
|
|
CP0373064
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C25H15F4N5O3
|
1
|
| 1 |
IC50 = 2070 nM
|
|
|
|
CP0455381
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-fluoro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C20H12ClF4N5O3
|
1
|
| 1 |
IC50 = 2170 nM
|
|
|
|
CP0205366
|
2-(4-Morpholinophenylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C22H23N5O2
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0400012
|
1-(5-tert-butyl-2-methylpyrazol-3-yl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C25H25N7O3
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0540417
|
(1R)-1-[6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophen-3-yl]-2,2,2-trifluoroethanol
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0505100
|
Pyridoimidazolone, 5a
Show/Hide
|
C20H13ClF3N5O3
|
1
|
| 1 |
IC50 = 2390 nM
|
|
|
|
CP0448925
|
1-[6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophen-3-yl]-2,2,2-trifluoroethanol
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0507512
|
1-(5-tert-butyl-2-methylpyrazol-3-yl)-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C22H25N7O3
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0309465
|
2-(3,5-Dimethoxyphenylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C20H20N4O3
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0319971
|
2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C20H18N4O3
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0431434
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[2-methylsulfanyl-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H15F4N5O3S
|
1
|
| 1 |
IC50 = 3060 nM
|
|
|
|
CP0917067
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-tertpentylbenzamide
Show/Hide
|
C25H25N3O3
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0383646
|
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[2-fluoro-4-(2H-triazolo[4,5-b]pyridin-7-yloxy)phenyl]urea
Show/Hide
|
C26H25FN8O2
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0499447
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C25H17ClF3N5O3
|
1
|
| 1 |
IC50 = 3140 nM
|
|
|
|
CP0389729
|
1-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[2-(4-methylphenyl)-5-(trifluoromethyl)pyrazol-3-yl]urea
Show/Hide
|
C25H20F3N7O3
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0285250
|
2-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-ylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C21H20N4O3
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0373065
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(3-methyl-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C26H17F4N5O3
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0455382
|
1-[2-fluoro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H13F4N5O3
|
1
|
| 1 |
IC50 = 3450 nM
|
|
|
|
CP0846908
|
3-Tert-butyl-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C24H23N3O3
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0401734
|
3-tert-butyl-N-[3-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]benzamide
Show/Hide
|
C24H22N4O3
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0497147
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C21H15F4N5O3
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0505103
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]-2-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H12ClF6N5O3
|
1
|
| 1 |
IC50 = 3580 nM
|
|
|
|
CP0205431
|
2,6-Disubstituted Pyrazine, 1
Show/Hide
|
C21H22N4O4
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0540598
|
7-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalen-2-ol
Show/Hide
|
C28H26N4O2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0388042
|
1-[2-fluoro-4-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-8-yl)oxyphenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C25H19F5N6O3
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0455383
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2,3-dimethyl-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C22H17ClF3N5O3
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0470686
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-methylsulfanyl-4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C22H15ClF3N5O3S
|
1
|
| 1 |
IC50 = 3990 nM
|
|
|
|
CP0161407
|
2-(3-Methoxyphenylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C19H18N4O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0522110
|
N-[3-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13F3N4O4
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0039590
|
3-(trifluoromethoxy)-N-[2,3,4-trifluoro-5-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]phenyl]benzamide
Show/Hide
|
C21H11F6N3O4
|
1
|
| 1 |
IC50 = 4050 nM
|
|
|
|
CP0455385
|
1-[2-fluoro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[3-(trifluoromethylsulfanyl)phenyl]urea
Show/Hide
|
C20H13F4N5O3S
|
1
|
| 1 |
IC50 = 4150 nM
|
|
|
|
CP0508291
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C21H13F4N5O3
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0407702
|
2-[4-[4-(2,4-dihydroindeno[1,2-d]triazol-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C27H25N7O
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0431435
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-methyl-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H15ClF3N5O3
|
1
|
| 1 |
IC50 = 4720 nM
|
|
|
|
CP0897174
|
1-(1-N-p-tolyl-3-trifluoromethyl-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C25H19F3N6O3
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0508288
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C21H13ClF3N5O3
|
1
|
| 1 |
IC50 = 4890 nM
|
|
|
|
CP0375833
|
6-(2-piperidin-4-yl-5-pyridin-4-yl-1H-imidazol-4-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C23H22N6
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0373070
|
N-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]benzamide
Show/Hide
|
C27H24N6O3
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0540595
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]isoquinolin-1-amine
Show/Hide
|
C27H26N6O
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0275080
|
2-[4-(Trifluoromethoxy)phenylamino]-6-(3-acetamidophenyl)-pyrazine
Show/Hide
|
C19H15F3N4O2
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0309466
|
2-[3-(2-Aminoethoxy)phenylamino]-6-(3-acetamidophenyl)-pyrazine
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0502353
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(2,3-dioxo-1,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C21H13ClF3N5O4
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0514499
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3-methoxy-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H15ClF3N5O4
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0897183
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(1,1,2,2-tetrafluoroethoxy)benzamide
Show/Hide
|
C22H15F4N3O4
|
1
|
| 1 |
IC50 = 5700 nM
|
|
|
|
CP0402327
|
2-[4-[4-(4,5-dihydro-1H-benzo[g]indazol-7-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C29H28N6O
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0479283
|
N,N-dimethyl-2-[4-[4-[4-(1H-pyrazol-5-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
|
C27H26N6O
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0448926
|
2-[4-[4-(3,4-dichlorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C24H22Cl2N4O
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0497137
|
1-[4-[[2-(dimethylamino)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-2-fluorophenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H17F5N6O2
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0018477
|
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H16ClF3N4O3
|
1
|
| 1 |
IC50 = 6100 nM
|
|
|
|
CP0371277
|
2-(3,4-Dimethoxyphenylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C20H20N4O3
|
1
|
| 1 |
IC50 = 6400 nM
|
|
|
|
CP0507516
|
1-(5-tert-butyl-2-pyridin-2-ylpyrazol-3-yl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C25H24N8O3
|
1
|
| 1 |
IC50 = 6400 nM
|
|
|
|
CP0897184
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-trifluoromethylthio-benzamide
Show/Hide
|
C21H14F3N3O3S
|
1
|
| 1 |
IC50 = 6480 nM
|
|
|
|
CP0470687
|
N-[3-[(2,3-dioxo-1,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13F3N4O5
|
1
|
| 1 |
IC50 = 6600 nM
|
|
|
|
CP0500251
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[2-methylsulfanyl-4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C22H15F4N5O3S
|
1
|
| 1 |
IC50 = 6600 nM
|
|
|
|
CP0846914
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-fluoro-3-trifluoromethoxy-benzamide
Show/Hide
|
C21H13F4N3O4
|
1
|
| 1 |
IC50 = 6700 nM
|
|
|
|
CP0897173
|
N-(2,4-difluoro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H12F5N3O4
|
1
|
| 1 |
IC50 = 6900 nM
|
|
|
|
CP0943550
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H14F3N3O4
|
1
|
| 1 |
IC50 = 7560 nM
|
|
|
|
CP0845260
|
3-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-N-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)benzamide
Show/Hide
|
C22H15F4N3O4
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0897172
|
N-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)benzamide
Show/Hide
|
C21H13ClF3N3O3
|
1
|
| 1 |
IC50 = 8200 nM
|
|
|
|
CP0205367
|
2-[4-(Morpholinosulfonyl)phenylamino]-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C22H23N5O4S
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0373066
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[[2-oxo-3-(trifluoromethyl)-1H-pyrido[2,3-b]pyrazin-8-yl]oxy]naphthalen-1-yl]urea
Show/Hide
|
C26H14F7N5O3
|
1
|
| 1 |
IC50 = 8500 nM
|
|
|
|
CP0500248
|
1-[2-fluoro-4-(1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H12F5N5O2
|
1
|
| 1 |
IC50 = 8500 nM
|
|
|
|
CP0309464
|
2-(2,4-Dimethoxyphenylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C20H20N4O3
|
1
|
| 1 |
IC50 = 8800 nM
|
|
|
|
CP0497136
|
1-[4-[(3-amino-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H13F5N6O3
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0470681
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-[[3-oxo-2-(trifluoromethyl)-4H-pyrido[2,3-b]pyrazin-8-yl]oxy]naphthalen-1-yl]urea
Show/Hide
|
C26H14F7N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0497138
|
1-[4-[[2-[(dimethylamino)methyl]-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-2-fluorophenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C23H19F5N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0523859
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[3-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C21H13F4N5O3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0372502
|
[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-[4-(1-methyl-4H-indeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]methanone
Show/Hide
|
C29H32N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0405630
|
2-[4-[4-[4-(4-chloro-1H-pyrazol-5-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C27H25ClN6O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0887313
|
1-(3-Tert-butyl-phenyl)-3-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C24H24N4O3
|
1
|
| 1 |
IC50 = 10300 nM
|
|
|
|
CP0845261
|
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)urea
Show/Hide
|
C21H14ClF3N4O3
|
1
|
| 1 |
IC50 = 10700 nM
|
|
|
|
CP0504320
|
1-(5-tert-butyl-2-propylpyrazol-3-yl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C23H27N7O3
|
1
|
| 1 |
IC50 = 10800 nM
|
|
|
|
CP0431433
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-methylsulfonyl-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H15ClF3N5O5S
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0897171
|
N-(3-chloro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13ClF3N3O4
|
1
|
| 1 |
IC50 = 11300 nM
|
|
|
|
CP0205370
|
2-(Phenylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C18H16N4O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0897170
|
1-(6-fluoro-3-(trifluoromethyl)phenyl)-3-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C21H14F4N4O3
|
1
|
| 1 |
IC50 = 12200 nM
|
|
|
|
CP0924128
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-(3-trifluoromethoxyphenyl)acetamide
Show/Hide
|
C21H16F3N3O5S
|
1
|
| 1 |
IC50 = 12800 nM
|
|
|
|
CP0897169
|
3-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-N-(3-(trifluoromethylthio)phenyl)benzamide
Show/Hide
|
C21H14F3N3O3S
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0477554
|
1-[2-fluoro-4-[(2-sulfanylidene-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H12F5N5O2S
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0374032
|
1-(2-benzyl-5-tert-butylpyrazol-3-yl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C27H27N7O3
|
1
|
| 1 |
IC50 = 13400 nM
|
|
|
|
CP0850037
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-5-(1-Nphenyl-3-tert-butyl)-pyrazolyl-amide
Show/Hide
|
C27H25N5O3
|
1
|
| 1 |
IC50 = 13700 nM
|
|
|
|
CP0874907
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-5-(1-Nphenyl-3-isopropyl)-pyrazolyl-amide
Show/Hide
|
C26H23N5O3
|
1
|
| 1 |
IC50 = 13700 nM
|
|
|
|
CP0488105
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalen-2-ol
Show/Hide
|
C28H26N4O2
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0429706
|
1-(5-tert-butyl-2-methylpyrazol-3-yl)-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C22H25N7O3
|
1
|
| 1 |
IC50 = 14100 nM
|
|
|
|
CP0850039
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-trifluoromethoxy-5-chloro-benzamide
Show/Hide
|
C21H13ClF3N3O4
|
1
|
| 1 |
IC50 = 14600 nM
|
|
|
|
CP0887315
|
3-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-N-(3-(trifluoromethoxy)phenyl)benzamide
Show/Hide
|
C21H14F3N3O4
|
1
|
| 1 |
IC50 = 14600 nM
|
|
|
|
CP0845254
|
3-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-N-(1-p-tolyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)benzamide
Show/Hide
|
C25H18F3N5O3
|
1
|
| 1 |
IC50 = 14800 nM
|
|
|
|
CP0920676
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-fluoro-5-trifluoromethoxy-benzamide
Show/Hide
|
C21H13F4N3O4
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
|
CP0850040
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-Npiperidinyl-benzamide
Show/Hide
|
C25H24N4O3
|
1
|
| 1 |
IC50 = 15400 nM
|
|
|
|
CP0917383
|
N-(3-fluoro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13F4N3O4
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0415242
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-fluoro-4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
Show/Hide
|
C21H12ClF4N5O3
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
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CP0470690
|
1-[2-fluoro-4-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-8-yl]oxyphenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C26H22F5N7O2
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0919065
|
N-(3-methoxy-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H16F3N3O5
|
1
|
| 1 |
IC50 = 16600 nM
|
|
|
|
CP0845255
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-(3-trifluoromethylphenyl)acetamide
Show/Hide
|
C21H16F3N3O4S
|
1
|
| 1 |
IC50 = 17800 nM
|
|
|
|
CP0334624
|
2-[(1,5-Dimethyl-1H-pyrazol-3-yl)methylamino]-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C17H18N6O
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0374339
|
1-(5-cyclopropyl-2-phenylpyrazol-3-yl)-3-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C26H23N7O3
|
1
|
| 1 |
IC50 = 18200 nM
|
|
|
|
CP0523272
|
N-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]-3-(trifluoromethylsulfanyl)benzamide
Show/Hide
|
C25H17F3N4O3S
|
1
|
| 1 |
IC50 = 18400 nM
|
|
|
|
CP0036032
|
1-(3-tert-butylphenyl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C27H25N5O3
|
1
|
| 1 |
IC50 = 19300 nM
|
|
|
|
CP0372546
|
1-[2-fluoro-4-[(3-methyl-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H14F5N5O3
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0388041
|
1-[4-[3-(dimethylamino)pyrido[2,3-b]pyrazin-8-yl]oxy-2-fluorophenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C23H17F5N6O2
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0874906
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-N-pyrrolylbenzamide
Show/Hide
|
C24H18N4O3
|
1
|
| 1 |
IC50 = 20400 nM
|
|
|
|
CP0505101
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(dimethylamino)-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C22H18ClF3N6O3
|
1
|
| 1 |
IC50 = 20700 nM
|
|
|
|
CP0846913
|
3-Fluoro-5-morpholino-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C24H21FN4O4
|
1
|
| 1 |
IC50 = 21100 nM
|
|
|
|
CP0887309
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)naphthalene-1-sulfonamide
Show/Hide
|
C23H17N3O4S
|
1
|
| 1 |
IC50 = 21300 nM
|
|
|
|
CP0887308
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-trifluoromethyl-5-chloro-benzamide
Show/Hide
|
C20H13ClF3N3O4S
|
1
|
| 1 |
IC50 = 23900 nM
|
|
|
|
CP0415241
|
1-[2-fluoro-4-(2H-triazolo[4,5-b]pyridin-7-yloxy)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C19H11F5N6O2
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0407701
|
2-[4-[4-(1H-benzo[g]indazol-7-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C29H26N6O
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0366128
|
2-(3-Chloro-4-fluorobenzylamino)-6-(3-acetamidophenyl)-pyrazine
Show/Hide
|
C19H16ClFN4O
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0917373
|
4-Fluoro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13F4N3O4
|
1
|
| 1 |
IC50 = 27700 nM
|
|
|
|
CP0447617
|
1-(5-tert-butyl-2-methylpyrazol-3-yl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H23N7O3
|
1
|
| 1 |
IC50 = 28000 nM
|
|
|
|
CP0887314
|
4-Chloro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H13ClF3N3O3
|
1
|
| 1 |
IC50 = 28000 nM
|
|
|
|
CP0845257
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1-naphtoylamide
Show/Hide
|
C24H17N3O3
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0505102
|
1-[3-methoxy-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H16F3N5O4
|
1
|
| 1 |
IC50 = 29400 nM
|
|
|
|
CP0846164
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzenesulfonamide
Show/Hide
|
C19H15N3O4S
|
1
|
| 1 |
IC50 = 29600 nM
|
|
|
|
CP0455384
|
N-[4-[(1-methyl-2-oxo-3H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]-3-(trifluoromethoxy)benzamide
Show/Hide
|
C25H17F3N4O4
|
1
|
| 1 |
IC50 = 31000 nM
|
|
|
|
CP0488107
|
N,N-dimethyl-2-[4-[4-(3-propylsulfanyl-1-benzothiophen-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
|
C29H30N4OS2
|
1
|
| 1 |
IC50 = 31000 nM
|
|
|
|
CP0161395
|
2-Phenoxyethylamino-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0285404
|
2-(3-Phenylpropylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C21H22N4O
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0538534
|
1-(2,5-ditert-butylpyrazol-3-yl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C24H29N7O3
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0505104
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3-fluoro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C20H12ClF4N5O3
|
1
|
| 1 |
IC50 = 34000 nM
|
|
|
|
CP0848902
|
N-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)benzamide
Show/Hide
|
C21H13F4N3O3
|
1
|
| 1 |
IC50 = 35000 nM
|
|
|
|
CP0850035
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-trifluoromethoxy-benzamide
Show/Hide
|
C21H14F3N3O4
|
1
|
| 1 |
IC50 = 35800 nM
|
|
|
|
CP0174014
|
2-(3,4,5-Trimethoxybenzylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C22H24N4O4
|
1
|
| 1 |
IC50 = 37000 nM
|
|
|
|
CP0534645
|
N-[3-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13F3N4O4
|
1
|
| 1 |
IC50 = 37000 nM
|
|
|
|
CP0275078
|
2-[(5-Methyl-3-isoxazolyl)methylamino]-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C17H17N5O2
|
1
|
| 1 |
IC50 = 38000 nM
|
|
|
|
CP0372395
|
2-(4-Methoxyphenyloxyethylamino)-6-(3-acetamidophenyl)-pyrazine
Show/Hide
|
C21H22N4O3
|
1
|
| 1 |
IC50 = 38000 nM
|
|
|
|
CP0887307
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C24H16F3N5O3
|
1
|
| 1 |
IC50 = 38000 nM
|
|
|
|
CP0897177
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-thiomorpholinoisonicotinamide
Show/Hide
|
C23H21N5O3S
|
1
|
| 1 |
IC50 = 38800 nM
|
|
|
|
CP0848912
|
1-(3,4-Difluorophenyl)-3-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C20H14F2N4O3
|
1
|
| 1 |
IC50 = 39000 nM
|
|
|
|
CP0852888
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-dimethylamino-benzamide
Show/Hide
|
C21H20N4O4S
|
1
|
| 1 |
IC50 = 42000 nM
|
|
|
|
CP0887306
|
1-(2-N-morpholyl-5-(trifluoromethyl)phenyl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C25H22F3N5O4
|
1
|
| 1 |
IC50 = 42000 nM
|
|
|
|
CP0272242
|
2-[3-(Oxazol-5-yl)phenylamino]-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C21H17N5O2
|
1
|
| 1 |
IC50 = 45000 nM
|
|
|
|
CP0470692
|
1-[2-fluoro-4-[3-(methylamino)pyrido[2,3-b]pyrazin-8-yl]oxyphenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H15F5N6O2
|
1
|
| 1 |
IC50 = 45000 nM
|
|
|
|
CP0504010
|
1-(3-tert-butylphenyl)-3-[4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C28H27N5O3
|
1
|
| 1 |
IC50 = 46000 nM
|
|
|
|
CP0036019
|
2-(Phenyl-N-methylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C19H19N5O
|
1
|
| 1 |
IC50 = 49600 nM
|
|
|
|
CP0902250
|
1-(3-Fluorophenyl)-3-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C20H15FN4O3
|
1
|
| 1 |
IC50 = 50200 nM
|
|
|
|
CP0846911
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C20H14F3N3O4S
|
1
|
| 1 |
IC50 = 57000 nM
|
|
|
|
CP0374341
|
1-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[5-(oxolan-2-yl)-1,3,4-thiadiazol-2-yl]urea
Show/Hide
|
C19H17N7O4S
|
1
|
| 1 |
IC50 = 58000 nM
|
|
|
|
CP0387816
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3-methyl-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H15ClF3N5O3
|
1
|
| 1 |
IC50 = 59000 nM
|
|
|
|
CP0874905
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-fluoro-3-trifluoromethyl-5-chloro-benzamide
Show/Hide
|
C20H12ClF4N3O4S
|
1
|
| 1 |
IC50 = 65000 nM
|
|
|
|
CP0846163
|
4-Chloro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C20H13ClF3N3O4S
|
1
|
| 1 |
IC50 = 66000 nM
|
|
|
|
CP0887312
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzo[b]thiophene-5-carboxamide
Show/Hide
|
C22H15N3O3S
|
1
|
| 1 |
IC50 = 66000 nM
|
|
|
|
CP0545326
|
1-[2-fluoro-4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H12F5N5O3
|
1
|
| 1 |
IC50 = 69000 nM
|
|
|
|
CP0374342
|
1-[2-(4-chlorophenyl)-5-methylpyrazol-3-yl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C23H18ClN7O3
|
1
|
| 1 |
IC50 = 70000 nM
|
|
|
|
CP0848901
|
1,3-Dimethyl-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
IC50 = 79000 nM
|
|
|
|
CP0874278
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1-phenyl-1Hpyrazole-5-carboxamide
Show/Hide
|
C23H17N5O3
|
1
|
| 1 |
IC50 = 92000 nM
|
|
|
|
CP0852889
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C20H14F3N3O5S
|
1
|
| 1 |
IC50 = 94000 nM
|
|
|
|
CP0407693
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-methoxy-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
C21H15ClF3N5O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0431428
|
1-(3,4-difluorophenyl)-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]urea
Show/Hide
|
C23H15F2N5O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0431429
|
N-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide
Show/Hide
|
C25H17F3N4O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0505991
|
N-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]naphthalen-1-yl]-2-[3-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C25H17F3N4O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0523271
|
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]-2-phenylphenyl]urea
Show/Hide
|
C26H17ClF3N5O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0059843
|
N-[3-[6-[(2,2,3,3-tetrafluoro-1,4-benzodioxin-5-yl)amino]pyrazin-2-yl]phenyl]acetamide
Show/Hide
|
C20H14F4N4O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0255237
|
2-(2-Pyridylmethylamino)-6-(3-acetamidophenyl)pyrazine
Show/Hide
|
C18H17N5O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0845256
|
4-Chloro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C19H14ClN3O4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0846910
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C20H15N3O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0846912
|
N-(2-chloro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13ClF3N3O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0848905
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-6-(3,4-dihydro-2H-benzo[b][1,4]-dioxepinoyl)amide
Show/Hide
|
C23H19N3O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0852890
|
N-(4-methoxy-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H16F3N3O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0859606
|
N-(2-methyl-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H16F3N3O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0866912
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-5-(2,3-dihydrobenzo[b]1,4-dioxinoyl)amide
Show/Hide
|
C22H17N3O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0874904
|
3-Bromo-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C20H14BrN3O3
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0887304
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzo[c][1,2,5]thiadiazole-5-carboxamide
Show/Hide
|
C20H15N5O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0887305
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N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-4-(trifluoromethyl)benzamide
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C20H14F3N3O4S
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1
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| 1 |
IC50 > 100000 nM
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CP0887311
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N-(4-methyl-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
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C22H16F3N3O4
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1
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| 1 |
IC50 > 100000 nM
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CP0887316
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1-Benzyl-3-tert-butyl-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1H-pyrazole-5-carboxamide
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C28H27N5O3
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1
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| 1 |
IC50 > 100000 nM
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CP0895174
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N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-N-pyrrolidyl-benzamide
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C24H22N4O3
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1
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| 1 |
IC50 > 100000 nM
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CP0895175
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N-(2,4-dichloro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
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C21H12Cl2F3N3O4
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1
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| 1 |
IC50 > 100000 nM
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CP0897166
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2-Chloro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)isonicotinamide
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C19H13ClN4O3
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1
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| 1 |
IC50 > 100000 nM
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CP0897167
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3-(1H-imidazol-1-yl)-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
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C23H17N5O3
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1
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| 1 |
IC50 > 100000 nM
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CP0897168
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N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-phenylpropanamide
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C21H19N3O4S
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1
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| 1 |
IC50 > 100000 nM
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CP0917374
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7-(3-(3-(Trifluoromethoxy)benzylamino)phenoxy)-1H-imidazo[4,5-b]pyridin-2(3H)-one
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C21H15F3N2O3
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1
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| 1 |
IC50 > 100000 nM
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CP0924127
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N-(2-methyl-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
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C22H16F3N3O4
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1
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| 1 |
IC50 > 100000 nM
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CP0924129
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N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-phenylacetamide
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C20H17N3O4S
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1
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| 1 |
IC50 > 100000 nM
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CP0470685
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1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
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C21H13ClF3N5O3
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1
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| 1 |
IC50 > 100000 nM
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CP0500683
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1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[3-[(2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
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C21H13F4N5O3
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1
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| 1 |
IC50 > 100000 nM
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CP0384792
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7-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2,4,4a,5-tetrahydroindeno[1,2-c]pyridazin-3-one
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C29H28N6O2
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1
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| 1 |
IC50 = 100000 nM
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CP0545374
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5-[4-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]phenyl]-1H-pyrazole-4-carbonitrile
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C28H25N7O
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1
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| 1 |
IC50 > 100000 nM
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