General Information of the Compound
| Compound ID |
CP0494261
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
1-[5-tert-butyl-2-(6-methylpyridin-3-yl)pyrazol-3-yl]-3-[2-fluoro-4-[(3-methyl-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]urea
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C27H27FN8O3
|
||||||||||||||||||
| Molecular Weight |
530.564
|
||||||||||||||||||
| Canonical SMILES |
Cc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3n(C)c(=O)[nH]c23)cc1F)C(C)(C)C
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C27H27FN8O3/c1-15-6-7-16(14-30-15)36-22(13-21(34-36)27(2,3)4)32-25(37)31-19-9-8-17(12-18(19)28)39-20-10-11-29-24-23(20)33-26(38)35(24)5/h6-14H,1-5H3,(H,33,38)(H2,31,32,37)
Show/Hide
|
||||||||||||||||||
| InChIKey |
SATKOPLRFNGESK-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound