Brief Information of the Compound and Protein
Compound Name
2-(2,4-Dimethoxyphenylamino)-6-(3-acetamidophenyl)pyrazine
    Show/Hide
PubChem ID
CID: 11581360
SID: 16683804
Canonical SMILES
COc1ccc(Nc2cncc(n2)-c2cccc(NC(C)=O)c2)c(OC)c1
    Show/Hide
Compound Formula C20H20N4O3
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000252 WM266-4 Homo sapiens (Human)  1
1
IC50 = 8800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21000 nM