Compound ID |
Compound Name |
Compound Formula |
CP0353545
|
(+/-)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinoline-5-carbaldehyde O-ethyl oxime
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C24H29N3O2
|
1
|
1 |
IC50 = 3.4 nM
|
|
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CP0056751
|
(+/-)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinoline-5-carbaldehyde O-tert-butyl oxime
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|
C26H33N3O2
|
1
|
1 |
IC50 = 3.8 nM
|
|
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CP0049750
|
(+/-)-(3R,4S)-7-fluoro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C21H23FN2O
|
1
|
1 |
IC50 = 4.1 nM
|
|
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CP0056753
|
(+/-)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinoline-5-carbaldehyde O-methyl oxime
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|
C23H27N3O2
|
1
|
1 |
IC50 = 4.2 nM
|
|
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CP0371255
|
(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 4-cyanophenylcarbamate
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|
C28H23ClF2N4O2
|
1
|
1 |
IC50 = 5 nM
|
|
|
CP0206803
|
(4Z)-4-ethoxyimino-5,7-difluoro-2,2-dimethyl-6-(3-methyl-1H-indol-7-yl)-1,3-dihydroquinolin-3-ol
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|
C22H23F2N3O2
|
1
|
1 |
IC50 = 5.2 nM
|
|
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CP0049753
|
(+/-)-(3R,4S)-5-fluoro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C21H23FN2O
|
1
|
1 |
IC50 = 7.1 nM
|
|
|
CP0181072
|
(+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C21H23ClN2O
|
1
|
1 |
IC50 = 7.8 nM
|
|
|
CP0353546
|
(+/-)-(3R,4S)-6-(1H-indol-7-yl)-2,2,4,5,8-pentamethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C22H26N2O
|
1
|
1 |
IC50 = 9.3 nM
|
|
|
CP0052526
|
(+/-)-(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C20H20F2N2O
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0242004
|
5,7-difluoro-2,2-dimethyl-6-(3-methyl-1H-indol-7-yl)-2,3-dihydroquinolin-4(1H)-one O-isopropyl oxime
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|
C23H25F2N3O
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0298248
|
(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 3-chloro-4-methoxyphenylcarbamate
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|
C28H25Cl2F2N3O3
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0160743
|
5,7-difluoro-2,2-dimethyl-6-(3-methyl-1H-indol-7-yl)-2,3-dihydroquinolin-4(1H)-one O-tert-butyl oxime
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|
C24H27F2N3O
|
1
|
1 |
IC50 = 13 nM
|
|
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CP0353543
|
(+/-)-(3R,4S)-5-chloro-8-fluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C20H20ClFN2O
|
1
|
1 |
IC50 = 14 nM
|
|
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CP0353544
|
(+/-)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinoline-5-carbaldehyde O-phenyl oxime
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|
C29H31N3O2
|
1
|
1 |
IC50 = 14.4 nM
|
|
|
CP0113425
|
(+/-)-(3R,4S)-8-chloro-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C20H19ClF2N2O
|
1
|
1 |
IC50 = 16 nM
|
|
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CP0113426
|
(+/-)-3-((3R,4S)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-5-yl)acrylonitrile
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|
C24H25N3O
|
1
|
1 |
IC50 = 16 nM
|
|
|
CP0288207
|
(+/-)-(3R,4S)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinoline-5-carbonitrile
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|
C22H23N3O
|
1
|
1 |
IC50 = 16 nM
|
|
|
CP0272638
|
(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 4-cyanophenylcarbamate
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|
C28H24F2N4O2
|
1
|
1 |
IC50 = 16 nM
|
|
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CP0333656
|
methyl 4-[[(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-3,4-dihydro-1H-quinolin-3-yl]oxycarbonylamino]benzoate
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|
C29H27F2N3O4
|
1
|
1 |
IC50 = 16 nM
|
|
|
CP0218142
|
(+/-)-(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl isopropylcarbamate
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|
C24H26ClF2N3O2
|
1
|
1 |
IC50 = 17 nM
|
|
|
CP0281237
|
(4Z)-5,7-difluoro-4-methoxyimino-2,2-dimethyl-6-(3-methyl-1H-indol-7-yl)-1,3-dihydroquinolin-3-ol
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|
C21H21F2N3O2
|
1
|
1 |
IC50 = 17 nM
|
|
|
CP0287158
|
(+/-)-(3R,4S)-5,7,8-trifluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C20H19F3N2O
|
1
|
1 |
IC50 = 19 nM
|
|
|
CP0206805
|
6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2-dimethyl-2,3-dihydroquinolin-4(1H)-one O-tert-butyl oxime
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|
C23H24ClF2N3O
|
1
|
1 |
IC50 = 19 nM
|
|
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CP0353542
|
(+/-)-(3R,4S)-7,8-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C20H20F2N2O
|
1
|
1 |
IC50 = 20 nM
|
|
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CP0257888
|
(+/-)-(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 3-acetylphenylcarbamate
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|
C29H27F2N3O3
|
1
|
1 |
IC50 = 22 nM
|
|
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CP0422817
|
6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-3-hydroxy-2,2-dimethyl-2,3-dihydroquinolin-4(1H)-one O-methyl oxime
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|
C20H18ClF2N3O2
|
1
|
1 |
IC50 = 22 nM
|
|
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CP0047174
|
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
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|
C21H28O5
|
1
|
1 |
IC50 = 23 nM
|
|
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CP0297515
|
(+/-)-(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl cyclohexylcarbamate
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|
C27H30ClF2N3O2
|
1
|
1 |
IC50 = 23 nM
|
|
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CP0052482
|
(+/-)-(3R,4S)-7-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C21H23ClN2O
|
1
|
1 |
IC50 = 26 nM
|
|
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CP0321172
|
(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 4-chlorophenylcarbamate
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|
C27H24ClF2N3O2
|
1
|
1 |
IC50 = 29 nM
|
|
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CP0225062
|
(+/-)-(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 4-acetylphenylcarbamate
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|
C29H27F2N3O3
|
1
|
1 |
IC50 = 31 nM
|
|
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CP0329293
|
(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 3-chloro-4-methoxyphenylcarbamate
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|
C28H26ClF2N3O3
|
1
|
1 |
IC50 = 31 nM
|
|
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CP0321171
|
(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl phenylcarbamate
Show/Hide
|
C27H24ClF2N3O2
|
1
|
1 |
IC50 = 33 nM
|
|
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CP0294135
|
(+/-)-(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 3-cyanophenylcarbamate
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|
C28H24F2N4O2
|
1
|
1 |
IC50 = 38 nM
|
|
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CP0225061
|
(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl 4-(dimethylamino)phenylcarbamate
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|
C29H30F2N4O2
|
1
|
1 |
IC50 = 39 nM
|
|
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CP0091080
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(+/-)-(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl benzylcarbamate
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|
C28H26ClF2N3O2
|
1
|
1 |
IC50 = 40 nM
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|
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CP0460331
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5,7-difluoro-6-(1H-indol-7-yl)-2,2-dimethyl-2,3-dihydroquinolin-4(1H)-one O-tert-butyl oxime
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|
C23H25F2N3O
|
1
|
1 |
IC50 = 40 nM
|
|
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CP0333655
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(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl benzo[d][1,3]dioxol-5-ylcarbamate
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|
C28H25F2N3O4
|
1
|
1 |
IC50 = 50 nM
|
|
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CP0298247
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(+/-)-(3R,4S)-6-(3-chloro-1H-indol-7-yl)-5,7-difluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl methylcarbamate
Show/Hide
|
C22H22ClF2N3O2
|
1
|
1 |
IC50 = 52 nM
|
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CP0206806
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5,7-difluoro-2,2-dimethyl-6-(3-methyl-1H-indol-7-yl)-2,3-dihydroquinolin-4(1H)-one O-1-hydroxy-2-methylpropan-2-yl oxime
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|
C24H27F2N3O2
|
1
|
1 |
IC50 = 65 nM
|
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CP0181071
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(+/-)-(3R,4S)-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-7-vinyl-1,2,3,4-tetrahydroquinolin-3-ol
Show/Hide
|
C23H26N2O
|
1
|
1 |
IC50 > 1000 nM
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CP0218632
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(+/-)-(3R,4S)-5,7-dichloro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-ol
Show/Hide
|
C20H20Cl2N2O
|
1
|
1 |
IC50 > 1000 nM
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|
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CP0261459
|
(+/-)-(3R,4S)-5-ethyl-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-3-ol
Show/Hide
|
C23H28N2O
|
1
|
1 |
IC50 > 1000 nM
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|
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CP0287369
|
(+/-)-(3R,4S)-6-(1H-indol-7-yl)-2,2,4,7,8-pentamethyl-1,2,3,4-tetrahydroquinolin-3-ol
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|
C22H26N2O
|
1
|
1 |
IC50 > 1000 nM
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|
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CP0288262
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(+/-)-(3R,4S)-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-7-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-3-ol
Show/Hide
|
C22H23F3N2O
|
1
|
1 |
IC50 > 1000 nM
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CP0292204
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(+/-)-(3R,4S)-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-5-vinyl-1,2,3,4-tetrahydroquinolin-3-ol
Show/Hide
|
C23H26N2O
|
1
|
1 |
IC50 > 1000 nM
|
|
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CP0295461
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(+/-)-(3R,4S)-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-3-ol
Show/Hide
|
C21H24N2O
|
1
|
1 |
IC50 > 1000 nM
|
|
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CP0776055
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(+/-)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinoline-5-carbaldehyde oxime
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|
C22H25N3O2
|
1
|
1 |
IC50 > 1000 nM
|
|
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CP0783981
|
(+/-)-4-((3R,4S)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-5-yl)but-3-en-2-one
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|
C25H28N2O2
|
1
|
1 |
IC50 > 1000 nM
|
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CP0281951
|
(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl phenylcarbamate
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|
C27H25F2N3O2
|
1
|
1 |
IC50 > 1000 nM
|
|
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CP0329292
|
(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl methyl(phenyl)carbamate
Show/Hide
|
C28H27F2N3O2
|
1
|
1 |
IC50 > 1000 nM
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CP0333652
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(+/-)-(3R,4S)-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-3-yl methylcarbamate
Show/Hide
|
C22H23F2N3O2
|
1
|
1 |
IC50 > 1000 nM
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