Brief Information of the Compound and Protein
Compound Name
1-[4-[(3-amino-2-oxo-1H-pyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]-3-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]urea
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PubChem ID
CID: 44132212
SID: 84984739
Canonical SMILES
Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3nc(N)c(=O)[nH]c23)cc1F)C(C)(C)C
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Compound Formula C28H27FN8O3
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000252 WM266-4 Homo sapiens (Human)  1
1
IC50 = 70 nM
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