General Information of the Compound
| Compound ID |
CP0388042
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| Compound Name |
1-[2-fluoro-4-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-8-yl)oxyphenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
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| Structure |
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| Formula |
C25H19F5N6O3
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| Molecular Weight |
546.456
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| Canonical SMILES |
Fc1ccc(cc1NC(=O)Nc1ccc(Oc2ccnc3nc(cnc23)N2CCOCC2)cc1F)C(F)(F)F
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| InChI |
InChI=1S/C25H19F5N6O3/c26-16-3-1-14(25(28,29)30)11-19(16)34-24(37)33-18-4-2-15(12-17(18)27)39-20-5-6-31-23-22(20)32-13-21(35-23)36-7-9-38-10-8-36/h1-6,11-13H,7-10H2,(H2,33,34,37)
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| InChIKey |
LTOAWKXCLMDTOH-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound