Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(3-Tert-butyl-1-(4-fluorophenyl)-1H-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
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 PubChem ID
CID: 46228509
Canonical SMILES
CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3cccc4[nH]c(=O)[nH]c34)c2)n(-c2ccc(F)cc2)n1
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Compound Formula C27H25FN6O3
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 123 nM
   TI
   LI
   LO
   TS
CL000252 WM266-4
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1960 nM
   TI
   LI
   LO
   TS