Brief Information of the Compound and Protein
Compound Name
1-[2-fluoro-4-[3-(4-methylpiperazin-1-yl)pyrido[2,3-b]pyrazin-8-yl]oxyphenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
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PubChem ID
CID: 44133016
SID: 84985579
Canonical SMILES
CN1CCN(CC1)c1cnc2c(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)c(F)c3)ccnc2n1
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Compound Formula C26H22F5N7O2
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000252 WM266-4 Homo sapiens (Human)  1
1
IC50 = 16000 nM
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