Brief Information of the Compound and Protein
Compound Name
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-fluoro-4-(3-morpholin-4-ylpyrido[2,3-b]pyrazin-8-yl)oxyphenyl]urea
    Show/Hide
PubChem ID
CID: 44132694
SID: 84985246
Canonical SMILES
CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4nc(cnc34)N3CCOCC3)cc2F)n(n1)-c1ccccc1
    Show/Hide
Compound Formula C31H31FN8O3
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000252 WM266-4 Homo sapiens (Human)  1
1
IC50 = 750 nM
   TI
   LI
   LO
   TS