Brief Information of the Compound and Protein
Compound Name
6-[2-[4-(4-methylpiperazin-1-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1,4-dihydroindeno[1,2-c]pyrazole
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PubChem ID
CID: 46937280
SID: 99445536
Canonical SMILES
CN1CCN(CC1)c1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc-2c(Cc3cn[nH]c-23)c1
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Compound Formula C29H27N7
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CL000252 WM266-4 Homo sapiens (Human)  1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS