Brief Information of the Compound and Protein
Compound Name
1-[3-methoxy-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
    Show/Hide
PubChem ID
CID: 44185065
SID: 85180383
Canonical SMILES
COc1cc(NC(=O)Nc2cccc(c2)C(F)(F)F)ccc1Oc1ccnc2[nH]c(=O)[nH]c12
    Show/Hide
Compound Formula C21H16F3N5O4
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000252 WM266-4 Homo sapiens (Human)  1
1
IC50 = 29400 nM
   TI
   LI
   LO
   TS