Brief Information of the Cell Line and Protein
Cell Line ID: CL000052 , A-431
Synonyms
A431
A431/P
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0037
Protein ID: PT00864 , Vascular endothelial growth factor receptor 2
Gene Name KDR
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P35968
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000052  Protein ID: PT00864
 
Compound ID Compound Name Compound Formula
CP0167979
4-N-(3-bromophenyl)-6-[(2-methylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C20H18BrN5
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0096083
4-N-(3-bromophenyl)-6-[(2,5-dimethoxyphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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C21H20BrN5O2
 1
1
IC50 = 620 nM
   TI
   LI
   LO
   TS
CP0008706
(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one
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C15H14N2O
 1
1
IC50 = 12900 nM
   TI
   LI
   LO
   TS
CP0091116
2-benzyl-N4-(3-bromophenyl)-1H-indole-4,6-diamine
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C19H16BrN5
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0497232
2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-pyrrolo[2,3-d]pyrimidine
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C20H18BrN5
 1
1
IC50 = 89200 nM
   TI
   LI
   LO
   TS