| Compound ID |
Compound Name |
Compound Formula |
|
CP0520539
|
US9199981, F35
Show/Hide
|
C22H17F4N5O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0577734
|
US9199981, F44
Show/Hide
|
C28H27F2N7O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0210538
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-[4-(2-methoxyethyl)piperazin-1-yl]propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C29H40N6O2
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0559630
|
US9199981, F59
Show/Hide
|
C25H24F2N6O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0564851
|
US9199981, F42
Show/Hide
|
C25H21F2N7O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0450746
|
US9199981, F102
Show/Hide
|
C23H19F4N5O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0516215
|
US9199981, F19
Show/Hide
|
C22H21N5O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0521524
|
US9199981, F40
Show/Hide
|
C24H19F2N7O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0512009
|
US9199981, F78
Show/Hide
|
C23H23N5O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0561336
|
US9199981, F41
Show/Hide
|
C26H23F2N7O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0170168
|
3-(2-aminoquinazolin-6-yl)-1-(3-fluoro-4-methylphenyl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C21H17FN4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0419925
|
US9199981, F12
Show/Hide
|
C24H23N5O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0425549
|
US9199981, F43
Show/Hide
|
C25H21F2N7O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0961360
|
US9199981, F14
Show/Hide
|
C23H22N6O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0138508
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-[4-(2-hydroxyethyl)piperazin-1-yl]propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C28H38N6O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0500381
|
US9199981, F25
Show/Hide
|
C22H18F3N5O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0559409
|
US9199981, F65
Show/Hide
|
C23H18F2N8O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0559629
|
US9199981, F46
Show/Hide
|
C24H18F2N6O2S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0166511
|
3-(2-aminoquinazolin-6-yl)-1-(4-chlorophenyl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C20H15ClN4O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0926438
|
US9199981, F7
Show/Hide
|
C22H20N6O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0137973
|
3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-(oxazol-2-yl)phenyl)pyridin-2(1H)-one
Show/Hide
|
C23H17N5O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0206230
|
3-(2-aminoquinazolin-6-yl)-1-(4-tert-butylphenyl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C24H24N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0400761
|
US9199981, F103
Show/Hide
|
C23H19F4N5O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0442553
|
US9199981, F48
Show/Hide
|
C27H24F3N7O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0559410
|
US9199981, F66
Show/Hide
|
C25H22F2N8O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0566714
|
US9199981, F30
Show/Hide
|
C22H19N5O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0566715
|
US9199981, F34
Show/Hide
|
C22H20F2N6O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0509244
|
US9199981, F75
Show/Hide
|
C24H21N5O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0137970
|
1-(4-(1H-pyrazol-1-yl)phenyl)-3-(2-aminoquinazolin-6-yl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C23H18N6O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0137971
|
3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-(trifluoromethyl)phenyl)pyridin-2(1H)-one
Show/Hide
|
C21H15F3N4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0206226
|
3-(2-aminoquinazolin-6-yl)-1-(4-methoxyphenyl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0310155
|
3-(2-aminoquinazolin-6-yl)-1-(4-fluoro-3-methylphenyl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C21H17FN4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0441747
|
phenyl N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamate
Show/Hide
|
C24H20N2O5
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0518809
|
US9199981, F58
Show/Hide
|
C23H23N5O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0424722
|
1-cyclohexyl-3-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]urea
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0166512
|
3-(2-aminoquinazolin-6-yl)-1-(4-chloro-3-fluorophenyl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C20H14ClFN4O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0561339
|
US9199981, F84
Show/Hide
|
C25H22F2N8O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0960211
|
US9199981, F4
Show/Hide
|
C21H18N6O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0521527
|
US9199981, F57
Show/Hide
|
C21H19N5O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0425553
|
US9199981, F93
Show/Hide
|
C20H18F2N4O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0515061
|
US9199981, F1
Show/Hide
|
C21H17F2N5O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0527310
|
US9199981, F5
Show/Hide
|
C23H21F2N5O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0512010
|
US9199981, F89
Show/Hide
|
C23H20F3N5O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0521523
|
US9199981, F38
Show/Hide
|
C24H23F2N5O4
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0564849
|
US9199981, F18
Show/Hide
|
C24H25N5O4
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0917683
|
US9199981, F32
Show/Hide
|
C24H23N5O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0545612
|
US9199981, F81
Show/Hide
|
C25H24F2N6O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0559411
|
US9199981, F70
Show/Hide
|
C22H19F2N5O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0576882
|
US9199981, F50
Show/Hide
|
C30H30F2N8O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0110944
|
1-cyclohexyl-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
Show/Hide
|
C23H26N4O4
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0137972
|
3-(2-aminoquinazolin-6-yl)-4-methyl-1-(3-(trifluoromethyl)phenyl)pyridin-2(1H)-one
Show/Hide
|
C21H15F3N4O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0206225
|
3-(2-aminoquinazolin-6-yl)-1-(3-methoxyphenyl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0463918
|
US9199981, F36
Show/Hide
|
C21H18FN5O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0378828
|
1-(2-cyclohexylethyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
Show/Hide
|
C25H30N4O4
|
1
|
| 1 |
IC50 < 30 nM
|
|
|
|
CP0441748
|
1-(2-cyclohexylethyl)-3-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]urea
Show/Hide
|
C26H31N3O4
|
1
|
| 1 |
IC50 < 30 nM
|
|
|
|
CP0206224
|
1-(4-acetylphenyl)-3-(2-aminoquinazolin-6-yl)-4-methylpyridin-2(1H)-one
Show/Hide
|
C22H18N4O2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0576883
|
US9199981, F54
Show/Hide
|
C26H27F2N5O3
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0556878
|
US9199981, F77
Show/Hide
|
C24H21F4N5O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0565679
|
US9199981, F72
Show/Hide
|
C21H16F3N5O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0442556
|
US9199981, F74
Show/Hide
|
C22H21N5O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0521526
|
US9199981, F49
Show/Hide
|
C27H28F2N6O4S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0559406
|
US9199981, F47
Show/Hide
|
C24H18F3N7O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0927505
|
US9199981, F15
Show/Hide
|
C25H24N6O3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0442557
|
US9199981, F76
Show/Hide
|
C25H22F2N6O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0520540
|
US9199981, F39
Show/Hide
|
C23H21F2N5O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0556877
|
US9199981, F68
Show/Hide
|
C24H20F2N6O4
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0425552
|
US9199981, F90
Show/Hide
|
C22H17F4N5O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0490807
|
US9199981, F105
Show/Hide
|
C21H19N5O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0503985
|
US9199981, F108
Show/Hide
|
C21H17F2N5O2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0927504
|
US9199981, F99
Show/Hide
|
C27H27F2N8O3+
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0556876
|
US9199981, F53
Show/Hide
|
C25H23F2N5O3
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0002778
|
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Show/Hide
|
C29H31N7O
|
2
|
| 1 |
IC50 = 46 nM
|
|
|
| 2 |
IC50 = 219 nM
|
|
|
|
CP0442854
|
US9199981, F111
Show/Hide
|
C22H20FN5O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0450745
|
US9199981, F97
Show/Hide
|
C23H20F3N5O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0515039
|
US9199981, F96
Show/Hide
|
C27H28F2N6O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0516188
|
US9199981, F87
Show/Hide
|
C20H15F2N5O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0561338
|
US9199981, F71
Show/Hide
|
C21H16F3N5O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0425551
|
US9199981, F86
Show/Hide
|
C24H22F3N5O3
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0559632
|
US9199981, F67
Show/Hide
|
C22H19F2N5O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0564850
|
US9199981, F20
Show/Hide
|
C22H21N5O3
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0490803
|
US9199981, F31
Show/Hide
|
C24H23N5O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0515062
|
US9199981, F9
Show/Hide
|
C24H23N5O4
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0515063
|
US9199981, F10
Show/Hide
|
C24H23N5O4
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0520545
|
US9199981, F106
Show/Hide
|
C21H18FN5O2
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0565678
|
US9199981, F64
Show/Hide
|
C20H15F2N5O2
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0527311
|
US9199981, F56
Show/Hide
|
C27H28F2N6O3
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0426293
|
US9199981, F8
Show/Hide
|
C23H21N5O4
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0463901
|
US9199981, F79
Show/Hide
|
C24H20F2N8O2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0419930
|
US9199981, F113
Show/Hide
|
C20H16FN5O2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0521521
|
US9199981, F22
Show/Hide
|
C21H20N6O4S
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0557969
|
US9199981, F112
Show/Hide
|
C22H20FN5O2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0871456
|
US9199981, F94
Show/Hide
|
C22H17F4N5O3
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0512679
|
US9199981, F104
Show/Hide
|
C20H17N5O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0509237
|
US9199981, F2
Show/Hide
|
C22H19N5O3
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0520536
|
US9199981, F26
Show/Hide
|
C23H22N6O4
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0521522
|
US9199981, F29
Show/Hide
|
C22H22N6O2
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0561335
|
US9199981, F24
Show/Hide
|
C22H20N6O4
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0463919
|
US9199981, F37
Show/Hide
|
C22H19F2N5O3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0442558
|
US9199981, F100
Show/Hide
|
C24H23N5O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0564852
|
US9199981, F88
Show/Hide
|
C20H15F2N5O2
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0957874
|
US9199981, F16
Show/Hide
|
C24H24N6O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0490806
|
US9199981, F101
Show/Hide
|
C20H16FN5O2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0556879
|
US9199981, F176
Show/Hide
|
C24H22F2N6O4
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0166510
|
ethyl 4-[3-(2-aminoquinazolin-6-yl)-4-methyl-2-oxopyridin-1-yl]benzoate
Show/Hide
|
C23H20N4O3
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0457028
|
1-cyclohexyl-3-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)thiourea
Show/Hide
|
C24H27N3O3S
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0520537
|
US9199981, F27
Show/Hide
|
C23H22N6O4
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0557968
|
US9199981, F85
Show/Hide
|
C23H18F5N5O3
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0576881
|
US9199981, F45
Show/Hide
|
C24H21N7O2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0166514
|
3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-morpholinophenyl)pyridin-2(1H)-one
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0559634
|
US9199981, F175
Show/Hide
|
C23H20F2N6O4
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0419929
|
US9199981, F95
Show/Hide
|
C25H21F2N7O2
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0490802
|
US9199981, F23
Show/Hide
|
C24H22N6O6
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0520543
|
US9199981, F82
Show/Hide
|
C24H19F2N7O2
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0518808
|
US9199981, F52
Show/Hide
|
C24H20F5N5O3
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0494682
|
2-Cyclohexylethyl N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]-phenyl}carbamate
Show/Hide
|
C26H30N2O5
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0520542
|
US9199981, F63
Show/Hide
|
C28H31F2N7O2
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0455987
|
US9199981, F107
Show/Hide
|
C21H18FN5O2
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0559407
|
US9199981, F51
Show/Hide
|
C29H27F3N8O3
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0561340
|
US9199981, F98
Show/Hide
|
C23H22FN5O3
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0520538
|
US9199981, F33
Show/Hide
|
C24H23N5O3
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0426294
|
US9199981, F21
Show/Hide
|
C25H26N6O4
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0442573
|
US9199981, F109
Show/Hide
|
C21H17F2N5O2
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0520541
|
US9199981, F60
Show/Hide
|
C22H16F2N6O2
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0565677
|
US9199981, F55a
Show/Hide
|
C22H21N5O3
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0559408
|
US9199981, F62
Show/Hide
|
C22H18F2N6O3
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0516216
|
US9199981, F28
Show/Hide
|
C22H22N6O4S
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0202808
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[1-(1,1-dioxo-1,4-thiazinan-4-yl)-2-methylpropan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C27H35N5O3S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0561322
|
US9199981, F138
Show/Hide
|
C21H16FN5O2
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0518963
|
US9199981, F130
Show/Hide
|
C24H24N6O4
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0425556
|
US9199981, F165
Show/Hide
|
C21H17F2N5O2
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0406774
|
US9199981, F166
Show/Hide
|
C21H18FN5O2
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0138507
|
5-cyano-N-[2-(cyclohexen-1-yl)-4-(2-morpholin-4-ylethyl)phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0503984
|
US9199981, F156
Show/Hide
|
C22H20FN5O2
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0569137
|
US9199981, F140
Show/Hide
|
C22H18F2N6O3
|
1
|
| 1 |
IC50 = 132 nM
|
|
|
|
CP0556880
|
US9199981, F122
Show/Hide
|
C21H19N5O3
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0490808
|
US9199981, F139
Show/Hide
|
C21H19N5O3
|
1
|
| 1 |
IC50 = 137 nM
|
|
|
|
CP0412201
|
US9199981, F163
Show/Hide
|
C25H21F2N7O2
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0527312
|
US9199981, F129
Show/Hide
|
C22H22N6O4S
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0484152
|
US9199981, F167
Show/Hide
|
C21H19N5O3
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0516750
|
US9199981, F134
Show/Hide
|
C20H14F3N5O2
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0512680
|
US9199981, F118
Show/Hide
|
C22H20N6O3
|
1
|
| 1 |
IC50 = 147 nM
|
|
|
|
CP0425555
|
US9199981, F142
Show/Hide
|
C23H22N6O4
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0569138
|
US9199981, F152
Show/Hide
|
C20H16FN5O2
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0408905
|
1-(cyclohexylmethyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]thiourea
Show/Hide
|
C24H28N4O3S
|
1
|
| 1 |
IC50 = 153 nM
|
|
|
|
CP0443661
|
US9199981, F162
Show/Hide
|
C23H21F2N5O3
|
1
|
| 1 |
IC50 = 157 nM
|
|
|
|
CP0536892
|
US9199981, F115
Show/Hide
|
C21H17F2N5O2
|
1
|
| 1 |
IC50 = 162 nM
|
|
|
|
CP0569136
|
US9199981, F119
Show/Hide
|
C21H16F3N5O2
|
1
|
| 1 |
IC50 = 162 nM
|
|
|
|
CP0412198
|
US9199981, F153
Show/Hide
|
C25H25F2N5O3
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0530579
|
US9199981, F150
Show/Hide
|
C23H20N8O2
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0508950
|
US9199981, F136
Show/Hide
|
C26H28N6O4
|
1
|
| 1 |
IC50 = 171 nM
|
|
|
|
CP0556882
|
US9199981, F158
Show/Hide
|
C22H20FN5O3
|
1
|
| 1 |
IC50 = 175 nM
|
|
|
|
CP0506741
|
US9199981, F151
Show/Hide
|
C21H18FN5O3
|
1
|
| 1 |
IC50 = 181 nM
|
|
|
|
CP0518964
|
US9199981, F137
Show/Hide
|
C21H20N6O2
|
1
|
| 1 |
IC50 = 197 nM
|
|
|
|
CP0161826
|
1-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-3-(2-phenylacetyl)thiourea
Show/Hide
|
C26H23N3O4S
|
1
|
| 1 |
IC50 = 202 nM
|
|
|
|
CP0520546
|
US9199981, F117
Show/Hide
|
C23H22N6O3
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0957875
|
US9199981, F126
Show/Hide
|
C27H29N7O4
|
1
|
| 1 |
IC50 = 213 nM
|
|
|
|
CP0549905
|
US9199981, F159
Show/Hide
|
C20H17N5O3
|
1
|
| 1 |
IC50 = 218 nM
|
|
|
|
CP0441745
|
N-[[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamothioyl]cyclohexanecarboxamide
Show/Hide
|
C25H27N3O4S
|
1
|
| 1 |
IC50 = 233 nM
|
|
|
|
CP0445570
|
N-[[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamoyl]-2-methylbenzamide
Show/Hide
|
C26H23N3O5
|
2
|
| 1 |
IC50 = 234 nM
|
|
|
| 2 |
IC50 = 434 nM
|
|
|
|
CP0521533
|
US9199981, F143
Show/Hide
|
C28H29F2N5O4
|
1
|
| 1 |
IC50 = 237 nM
|
|
|
|
CP0556881
|
US9199981, F145
Show/Hide
|
C28H31F2N7O3
|
1
|
| 1 |
IC50 = 238 nM
|
|
|
|
CP0576407
|
US9199981, F144
Show/Hide
|
C27H29F2N7O2
|
1
|
| 1 |
IC50 = 249 nM
|
|
|
|
CP0252053
|
5-cyano-N-[4-[2-[2-(dimethylamino)ethoxy]propan-2-yl]-2-(4,4-dimethylcyclohexen-1-yl)phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C26H35N5O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0357111
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(2-hydroxyethylamino)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C24H31N5O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0442856
|
US9199981, F124
Show/Hide
|
C25H26N6O3
|
1
|
| 1 |
IC50 = 257 nM
|
|
|
|
CP0530580
|
US9199981, F160
Show/Hide
|
C22H19F2N5O2
|
1
|
| 1 |
IC50 = 293 nM
|
|
|
|
CP0172898
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-(2-morpholin-4-ylethyl)phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C25H31N5O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0435526
|
1-benzyl-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]thiourea
Show/Hide
|
C24H22N4O3S
|
1
|
| 1 |
IC50 = 303 nM
|
|
|
|
CP0549904
|
US9199981, F148
Show/Hide
|
C20H17N5O3
|
1
|
| 1 |
IC50 = 305 nM
|
|
|
|
CP0188938
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[1-(2-methoxyethylamino)-2-methylpropan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C26H35N5O2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0521531
|
US9199981, F131
Show/Hide
|
C20H18N6O2
|
1
|
| 1 |
IC50 = 311 nM
|
|
|
|
CP0559635
|
US9199981, F114
Show/Hide
|
C20H17N5O2
|
1
|
| 1 |
IC50 = 322 nM
|
|
|
|
CP0536893
|
US9199981, F123
Show/Hide
|
C26H28N6O2
|
1
|
| 1 |
IC50 = 345 nM
|
|
|
|
CP0412196
|
US9199981, F147
Show/Hide
|
C26H21F2N7O4
|
1
|
| 1 |
IC50 = 351 nM
|
|
|
|
CP0518962
|
US9199981, F127
Show/Hide
|
C26H28N6O4
|
1
|
| 1 |
IC50 = 353 nM
|
|
|
|
CP0128902
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[1-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpropan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C29H40N6O2
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0450750
|
US9199981, F154
Show/Hide
|
C25H22F2N6O4
|
1
|
| 1 |
IC50 = 365 nM
|
|
|
|
CP0450749
|
US9199981, F149
Show/Hide
|
C22H17F4N5O3
|
1
|
| 1 |
IC50 = 378 nM
|
|
|
|
CP0179797
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(2-pyrrolidin-1-ylethoxy)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C28H37N5O2
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0569139
|
US9199981, F155
Show/Hide
|
C25H25F2N5O3
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0536895
|
US9199981, F141
Show/Hide
|
C24H21F3N6O4
|
1
|
| 1 |
IC50 = 391 nM
|
|
|
|
CP0940699
|
US9199981, F125
Show/Hide
|
C26H29N7O2
|
1
|
| 1 |
IC50 = 393 nM
|
|
|
|
CP0202806
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(2-morpholin-4-ylethylamino)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C28H38N6O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0957877
|
US9199981, F133
Show/Hide
|
C24H26N6O3
|
1
|
| 1 |
IC50 = 451 nM
|
|
|
|
CP0171697
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(4-methylpiperazin-1-yl)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C27H36N6O
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0429118
|
US9199981, F168
Show/Hide
|
C21H17FN6O3
|
1
|
| 1 |
IC50 = 516 nM
|
|
|
|
CP0210539
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(2-methoxyethylamino)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C25H33N5O2
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0325690
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[[4-(2-hydroxyethyl)piperazin-1-yl]methyl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C26H34N6O2
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0557970
|
US9199981, F169
Show/Hide
|
C26H26F2N6O2
|
1
|
| 1 |
IC50 = 539 nM
|
|
|
|
CP0536894
|
US9199981, F132
Show/Hide
|
C23H22N6O4
|
1
|
| 1 |
IC50 = 554 nM
|
|
|
|
CP0222021
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(4-ethylpiperazin-1-yl)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C28H38N6O
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0382395
|
N-[[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]carbamoyl]-2-methylbenzamide
Show/Hide
|
C25H22N4O5
|
1
|
| 1 |
IC50 = 623 nM
|
|
|
|
CP0442494
|
2-chloro-N-[[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamothioyl]benzamide
Show/Hide
|
C25H20ClN3O4S
|
1
|
| 1 |
IC50 = 637 nM
|
|
|
|
CP0117532
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-methyl-1-(2-methylsulfonylethylamino)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C26H35N5O3S
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0155494
|
5-cyano-N-[2-(cyclohexen-1-yl)-4-(morpholin-4-ylmethyl)phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C22H25N5O2
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0445571
|
N-[[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamothioyl]benzamide
Show/Hide
|
C25H21N3O4S
|
1
|
| 1 |
IC50 = 938 nM
|
|
|
|
CP0425554
|
US9199981, F135
Show/Hide
|
C24H22F3N5O3
|
1
|
| 1 |
IC50 = 999 nM
|
|
|
|
CP0333107
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea
Show/Hide
|
C28H21F4N5O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0103171
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(2-morpholin-4-ylethoxy)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C28H37N5O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0339359
|
5-cyano-N-[2-(cyclohexen-1-yl)-4-(2-hydroxyethyl)phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0226619
|
N-[4-[1-(4-acetylpiperazin-1-yl)-2-methylpropan-2-yl]-2-(4,4-dimethylcyclohexen-1-yl)phenyl]-5-cyano-1H-imidazole-2-carboxamide
Show/Hide
|
C29H38N6O2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0329151
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(2-methylsulfonylethylamino)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C25H33N5O3S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0341600
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-(1-hydroxy-2-methylpropan-2-yl)phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0556011
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-(2-hydroxyethyl)phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0334249
|
5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-(2-hydroxypropan-2-yl)phenyl]-1H-imidazole-2-carboxamide
Show/Hide
|
C22H26N4O2
|
1
|
| 1 |
IC50 = 2500 nM
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|
|
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CP0226616
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5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-(2-morpholin-4-ylpropan-2-yl)phenyl]-1H-imidazole-2-carboxamide
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C26H33N5O2
|
1
|
| 1 |
IC50 = 3000 nM
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|
|
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CP0202805
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5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(1,1-dioxo-1,4-thiazinan-4-yl)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
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|
C26H33N5O3S
|
1
|
| 1 |
IC50 = 3300 nM
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|
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CP0173527
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5-cyano-N-[2-(4,4-dimethylcyclohexen-1-yl)-4-[2-(pyridin-2-ylamino)propan-2-yl]phenyl]-1H-imidazole-2-carboxamide
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|
C27H30N6O
|
1
|
| 1 |
IC50 = 4000 nM
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|
|
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CP0456025
|
US9199981, F170
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C24H26N6O3
|
1
|
| 1 |
IC50 = 4280 nM
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|
|
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CP0412203
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US9199981, F173
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C22H17F2N9O2
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0518965
|
US9199981, F171
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C24H21F2N5O4
|
1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0959315
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US9199981, F172
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|
C25H26FN5O4
|
1
|
| 1 |
IC50 > 10000 nM
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|
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