General Information of the Cell Line
Cell Line ID
CL000752
Cell Line Name
PBMC iPSC #1
Category
Induced pluripotent stem cell
Organism
Homo sapiens (Human)
Tissue Information
Peripheral blood
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01107, 11-beta-hydroxysteroid dehydrogenase 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0544885
 Compound Info 
(3R)-1'-[1-(4-chlorophenyl)cyclopropanecarbonyl]spiro[2-benzofuran-3,3'-pyrrolidine]-1-one
   Show/Hide
C21H18ClNO3
  1
1
IC50 = 0.6 nM
 Bioactivity Info 
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CP0579722
 Compound Info 
(1R)-1'-[1-(4-chlorophenyl)cyclopropanecarbonyl]spiro[furo[3,4-c]pyridine-1,3'-pyrrolidine]-3-one
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C20H17ClN2O3
  1
1
IC50 = 1 nM
 Bioactivity Info 
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CP0579726
 Compound Info 
N-methyl-5-[4-[1-[(1R)-3-oxospiro[2-benzofuran-1,3'-pyrrolidine]-1'-carbonyl]cyclopropyl]phenyl]pyridine-2-carboxamide
   Show/Hide
C28H25N3O4
  1
1
IC50 = 1.1 nM
 Bioactivity Info 
   TI
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CP0579724
 Compound Info 
(3R)-1'-[1-(4-pyridin-3-ylphenyl)cyclopropanecarbonyl]spiro[2-benzofuran-3,3'-pyrrolidine]-1-one
   Show/Hide
C26H22N2O3
  1
1
IC50 = 1.2 nM
 Bioactivity Info 
   TI
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CP0575306
 Compound Info 
(3R,5S)-7-cyclohexyl-1-(1-cyclohexylethyl)-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C21H36N2O2
  1
1
IC50 = 1.9 nM
 Bioactivity Info 
   TI
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CP0576720
 Compound Info 
(3R)-1'-[1-(6-phenylpyridin-3-yl)cyclopropanecarbonyl]spiro[2-benzofuran-3,3'-pyrrolidine]-1-one
   Show/Hide
C26H22N2O3
  1
1
IC50 = 2.2 nM
 Bioactivity Info 
   TI
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CP0579723
 Compound Info 
(3R)-1'-[1-(4-pyridin-2-ylphenyl)cyclopropanecarbonyl]spiro[2-benzofuran-3,3'-pyrrolidine]-1-one
   Show/Hide
C26H22N2O3
  1
1
IC50 = 3 nM
 Bioactivity Info 
   TI
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CP0579725
 Compound Info 
N-methyl-6-[4-[1-[(1R)-3-oxospiro[2-benzofuran-1,3'-pyrrolidine]-1'-carbonyl]cyclopropyl]phenyl]pyridine-3-carboxamide
   Show/Hide
C28H25N3O4
  1
1
IC50 = 3.7 nM
 Bioactivity Info 
   TI
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CP0573674
 Compound Info 
(3R,5S)-1-(1-cyclobutylethyl)-7-cyclohexyl-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C19H32N2O2
  1
1
IC50 = 3.9 nM
 Bioactivity Info 
   TI
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CP0543236
 Compound Info 
(3R)-1'-[1-(4-pyridin-4-ylphenyl)cyclopropanecarbonyl]spiro[2-benzofuran-3,3'-pyrrolidine]-1-one
   Show/Hide
C26H22N2O3
  1
1
IC50 = 4.2 nM
 Bioactivity Info 
   TI
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CP0577651
 Compound Info 
N,N-dimethyl-5-[4-[1-[(1R)-3-oxospiro[2-benzofuran-1,3'-pyrrolidine]-1'-carbonyl]cyclopropyl]phenyl]pyridine-2-carboxamide
   Show/Hide
C29H27N3O4
  1
1
IC50 = 4.6 nM
 Bioactivity Info 
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CP0577449
 Compound Info 
5-[4-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]-2-fluorophenyl]-N-propan-2-ylpyridine-2-carboxamide
   Show/Hide
C29H37FN4O3
  1
1
IC50 = 4.9 nM
 Bioactivity Info 
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CP0578772
 Compound Info 
N,N-dimethyl-6-[4-[1-[(1R)-3-oxospiro[2-benzofuran-1,3'-pyrrolidine]-1'-carbonyl]cyclopropyl]phenyl]pyridine-3-carboxamide
   Show/Hide
C29H27N3O4
  1
1
IC50 = 5 nM
 Bioactivity Info 
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CP0573676
 Compound Info 
(3S,5S)-1-[(4-chlorophenyl)methyl]-7-cyclohexyl-3-fluoro-1,7-diazaspiro[4.4]nonan-6-one
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C20H26ClFN2O
  1
1
IC50 = 5.1 nM
 Bioactivity Info 
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CP0545282
 Compound Info 
5-[4-[[(3S,5S)-7-cyclohexyl-3-fluoro-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]phenyl]-N-methylpyridine-2-carboxamide
   Show/Hide
C27H33FN4O2
  1
1
IC50 = 5.9 nM
 Bioactivity Info 
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CP0577448
 Compound Info 
(3R,5S)-1-[(4-chlorophenyl)methyl]-7-cyclohexyl-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C20H27ClN2O2
  1
1
IC50 = 6.2 nM
 Bioactivity Info 
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CP0570998
 Compound Info 
(3R,5S)-7-cyclohexyl-3-hydroxy-1-[(4-pyridin-4-ylphenyl)methyl]-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C25H31N3O2
  1
1
IC50 = 6.6 nM
 Bioactivity Info 
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CP0578968
 Compound Info 
(3R,5S)-7-cyclohexyl-1-(cyclohexylmethyl)-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C20H34N2O2
  1
1
IC50 = 7 nM
 Bioactivity Info 
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CP0573675
 Compound Info 
5-[4-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]phenyl]-N-methylpyridine-2-carboxamide
   Show/Hide
C27H34N4O3
  1
1
IC50 = 7.2 nM
 Bioactivity Info 
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CP0576224
 Compound Info 
5-[4-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]-2-fluorophenyl]-N-methylpyridine-2-carboxamide
   Show/Hide
C27H33FN4O3
  1
1
IC50 = 9.5 nM
 Bioactivity Info 
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CP0550050
 Compound Info 
N,N-dimethyl-4-[5-[1-[(1R)-3-oxospiro[2-benzofuran-1,3'-pyrrolidine]-1'-carbonyl]cyclopropyl]pyridin-2-yl]benzamide
   Show/Hide
C29H27N3O4
  1
1
IC50 = 9.5 nM
 Bioactivity Info 
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CP0575165
 Compound Info 
5-[4-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]-3-fluorophenyl]-N-methylpyridine-2-carboxamide
   Show/Hide
C27H33FN4O3
  1
1
IC50 = 17 nM
 Bioactivity Info 
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CP0367898
 Compound Info 
(3S,5S)-7-cyclohexyl-1-ethyl-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C15H26N2O2
  1
1
IC50 = 21 nM
 Bioactivity Info 
   TI
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CP0569045
 Compound Info 
N-methyl-4-[5-[1-[(1R)-3-oxospiro[2-benzofuran-1,3'-pyrrolidine]-1'-carbonyl]cyclopropyl]pyridin-2-yl]benzamide
   Show/Hide
C28H25N3O4
  1
1
IC50 = 21 nM
 Bioactivity Info 
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CP0580031
 Compound Info 
4-[5-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]pyridin-2-yl]benzonitrile
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C26H30N4O2
  1
1
IC50 = 35 nM
 Bioactivity Info 
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CP0543357
 Compound Info 
N-methyl-3-[5-[1-[(1R)-3-oxospiro[2-benzofuran-1,3'-pyrrolidine]-1'-carbonyl]cyclopropyl]pyridin-2-yl]benzamide
   Show/Hide
C28H25N3O4
  1
1
IC50 = 40 nM
 Bioactivity Info 
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CP0577650
 Compound Info 
(3R)-1'-(1-pyridin-3-ylcyclopropanecarbonyl)spiro[2-benzofuran-3,3'-pyrrolidine]-1-one
   Show/Hide
C20H18N2O3
  1
1
IC50 = 120 nM
 Bioactivity Info 
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CP0571014
 Compound Info 
(3R)-1'-(1-pyridin-4-ylcyclopropanecarbonyl)spiro[2-benzofuran-3,3'-pyrrolidine]-1-one
   Show/Hide
C20H18N2O3
  1
1
IC50 = 150 nM
 Bioactivity Info 
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CP0543803
 Compound Info 
(3R,5S)-7-cyclohexyl-1-(1-cyclopropylethyl)-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C18H30N2O2
  1
1
IC50 > 37 nM
 Bioactivity Info 
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CP0545283
 Compound Info 
(3S,5R)-1-[(4-chlorophenyl)methyl]-7-cyclohexyl-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C20H27ClN2O2
  1
1
IC50 > 37 nM
 Bioactivity Info 
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CP0545284
 Compound Info 
3-[5-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]pyridin-2-yl]benzonitrile
   Show/Hide
C26H30N4O2
  1
1
IC50 > 37 nM
 Bioactivity Info 
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CP0545285
 Compound Info 
5-[5-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]-2-fluorophenyl]-N-ethylpyridine-2-carboxamide
   Show/Hide
C28H35FN4O3
  1
1
IC50 > 37 nM
 Bioactivity Info 
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CP0573482
 Compound Info 
(3R,5S)-7-cyclohexyl-3-hydroxy-1-propan-2-yl-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C16H28N2O2
  1
1
IC50 > 37 nM
 Bioactivity Info 
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CP0577515
 Compound Info 
5-[3-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]phenyl]-N-ethylpyridine-2-carboxamide
   Show/Hide
C28H36N4O3
  1
1
IC50 > 37 nM
 Bioactivity Info 
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CP0578967
 Compound Info 
(5S)-1-[(4-chlorophenyl)methyl]-7-cyclohexyl-3-hydroxy-3-methyl-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C21H29ClN2O2
  1
1
IC50 > 37 nM
 Bioactivity Info 
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CP0579331
 Compound Info 
(3R,5S)-7-cyclohexyl-1-[[6-(4-fluorophenyl)pyridin-3-yl]methyl]-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
   Show/Hide
C25H30FN3O2
  1
1
IC50 > 37 nM
 Bioactivity Info 
   TI
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Protein ID: PT01070, C-C chemokine receptor type 1
 Protein Info 
Protein ID: PT01021, C-C chemokine receptor type 2
 Protein Info 
Protein ID: PT01215, C-C chemokine receptor type 3
 Protein Info 
Protein ID: PT00903, C-C chemokine receptor type 5
 Protein Info 
Protein ID: PT02805, CREB-binding protein
 Protein Info 
Protein ID: PT02509, G-protein coupled bile acid receptor 1
 Protein Info 
Protein ID: PT00645, Glucocorticoid receptor
 Protein Info 
Protein ID: PT00870, Glucocorticoid receptor
 Protein Info 
Protein ID: PT00967, Glucocorticoid receptor
 Protein Info 
Protein ID: PT07390, Glucocorticoid receptor
 Protein Info 
Protein ID: PT01760, Interleukin-1 receptor type 1
 Protein Info 
Protein ID: PT00821, Interleukin-1 receptor-associated kinase 4
 Protein Info 
Protein ID: PT03614, NACHT, LRR and PYD domains-containing protein 3
 Protein Info 
Protein ID: PT01540, Non-receptor tyrosine-protein kinase TYK2
 Protein Info 
Protein ID: PT02663, Nuclear receptor ROR-gamma
 Protein Info 
Protein ID: PT00999, PIK3CD
 Protein Info 
Protein ID: PT00004, Pol polyprotein
 Protein Info 
Protein ID: PT03168, Proteasome subunit beta type-8
 Protein Info 
Protein ID: PT01127, Protein kinase C theta type
 Protein Info 
Protein ID: PT03734, Sepiapterin reductase
 Protein Info 
Protein ID: PT01058, Snake venom-like protease
 Protein Info 
Protein ID: PT03644, Stimulator of interferon genes protein
 Protein Info 
Protein ID: PT06366, Toll-like receptor 1
 Protein Info 
Protein ID: PT04438, Toll-like receptor 2
 Protein Info 
Protein ID: PT03343, Toll-like receptor 4
 Protein Info 
Protein ID: PT06115, Toll-like receptor 5
 Protein Info 
Protein ID: PT02160, Toll-like receptor 7
 Protein Info 
Protein ID: PT02546, Toll-like receptor 8
 Protein Info 
Protein ID: PT01922, Toll-like receptor 9
 Protein Info 
Protein ID: PT02347, Tumor necrosis factor
 Protein Info 
Protein ID: PT01308, Tyrosine-protein kinase BTK
 Protein Info 
Protein ID: PT01214, Tyrosine-protein kinase JAK2
 Protein Info 
Protein ID: PT00892, Tyrosine-protein kinase JAK3
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003494
 Compound Info 
US9187397, 1 (curcumin)
   Show/Hide
 C21H20O6  1
1
IC50 = 34800 nM
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CP0024129
 Compound Info 
3-[4-amino-7-[2-(dimethylamino)ethyl]pyrrolo[2,3-d]pyrimidin-5-yl]phenol
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 C16H19N5O  1
1
IC50 > 10000 nM
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CP0028620
 Compound Info 
AEB071
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 C25H22N6O2  1
1
IC50 = 28 nM
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CP0035405
 Compound Info 
7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methylpropyl)-6-(naphthalen-1-ylmethyl)-1H,2H,6H-pyrrolo[3,4-d]pyridazin-1-one
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 C25H29N3O2S  1
1
IC50 = 0.3802 nM
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CP0036222
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
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 C62H111N11O12  1
1
IC50 = 3 nM
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CP0037308
 Compound Info 
(R,S)-Rolipram
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 C16H21NO3  1
1
IC50 > 30000 nM
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CP0037987
 Compound Info 
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
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 C22H23N3O4  1
1
IC50 = 39320 nM
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CP0040550
 Compound Info 
([5-(4-Methyl-1-piperazinyl)-2-({methyl[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]amino}methyl)imidazo[1,2-a]pyridin-3-yl]methanol)
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 C24H32N6O  1
1
IC50 > 1000 nM
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CP0040937
 Compound Info 
1-allyl-1-((1R,3S,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)-3-(4-(trifluoromethyl)benzyl)urea
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 C36H44F4N4O3  1
1
CC50 = 12500 nM
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CP0052231
 Compound Info 
N-[[4-(4-acetylpiperazin-1-yl)phenyl]methyl]-N-cyclobutyl-1-phenylmethanesulfonamide
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 C24H31N3O3S  1
1
EC50 > 10000 nM
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CP0053690
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-diethyl-33-((1R,2R)-1-hydroxy-2-methylhex-4-enyl)-6,9,18-triisobutyl-3,21,24-triisopropyl-1,4,7,10,12,15,19,27,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
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 C63H113N11O12  1
1
IC50 = 500 nM
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CP0058616
 Compound Info 
5-Hydroxy-2-methyl-[1,4]naphthoquinone
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 C11H8O3  1
1
IC50 = 2700 nM
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CP0071651
 Compound Info 
4-[[4-(4-benzyl-1H-pyrazol-5-yl)piperidin-1-yl]methyl]pyridine
   Show/Hide
 C21H24N4  1
1
TC50 > 100000 nM
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CP0073219
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[[2-(oxan-4-yl)acetyl]-(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
 C29H41ClN4O3S  1
1
CC50 > 35600 nM
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CP0084929
 Compound Info 
1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-heptane-3,5-dione
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 C21H24O6  1
1
IC50 > 50000 nM
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CP0092203
 Compound Info 
3-[2-chloro-6-[(dimethylamino)methyl]naphthalen-1-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
   Show/Hide
 C25H20ClN3O2  1
1
IC50 = 59 nM
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CP0096608
 Compound Info 
2-[[2-(tert-butylamino)-1-(4-fluorophenyl)-2-oxoethyl]-methylamino]ethyl (E)-4-(4-fluorophenyl)-4-oxobut-2-enoate
   Show/Hide
 C25H28F2N2O4  1
1
IC50 = 55710 nM
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CP0097118
 Compound Info 
4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-2-ylpropyl]cyclohexane-1-carboxamide
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 C27H39F2N5OS  1
1
CC50 = 268 nM
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CP0097120
 Compound Info 
N-[(1S)-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-2-ylpropyl]cyclohexanecarboxamide
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 C27H41N5OS  1
1
CC50 = 266.7 nM
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CP0115322
 Compound Info 
(1E,6E)-1,7-bis(3-fluoro-4-hydroxy-5-methoxyphenyl)hepta-1,6-diene-3,5-dione
   Show/Hide
 C21H18F2O6  1
1
IC50 > 50000 nM
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CP0118632
 Compound Info 
N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-2-ylpropyl]cyclopentanecarboxamide
   Show/Hide
 C26H39N5OS  1
1
CC50 = 755 nM
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CP0125375
 Compound Info 
4-((3-allyl-3-((1R,3S,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)ureido)methyl)-N,N-dimethylbenzenesulfonamide
   Show/Hide
 C37H50FN5O5S  1
1
CC50 = 55000 nM
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   TS
CP0139044
 Compound Info 
5-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4,6-dimethyl-2-N-propan-2-ylpyridine-2,5-dicarboxamide
   Show/Hide
 C28H42N6O4S  1
1
CC50 > 35800 nM
   TI
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   LO
   TS
CP0153862
 Compound Info 
4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one
   Show/Hide
 C21H18O5  3
1
EC50 = 400 nM
   TI
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2
EC50 = 430 nM
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3
EC50 = 25000 nM
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CP0159148
 Compound Info 
5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methylpropyl)-6-(naphthalen-1-ylmethyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione
   Show/Hide
 C25H28N2O3S2  1
1
IC50 = 0.2344 nM
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CP0164464
 Compound Info 
2-methyl-3-propan-2-ylsulfanylnaphthalene-1,4-dione
   Show/Hide
 C14H14O2S  1
1
IC50 = 8900 nM
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CP0172933
 Compound Info 
5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-6-(1H-indol-3-ylmethyl)-3-methyl-1-(2-methylpropyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione
   Show/Hide
 C25H28N4O4S  1
1
IC50 = 0.912 nM
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CP0187559
 Compound Info 
N-[[4-(4-acetylpiperazin-1-yl)-2-fluorophenyl]methyl]-N-cyclobutyl-1-(2-fluorophenyl)methanesulfonamide
   Show/Hide
 C24H29F2N3O3S  1
1
EC50 > 20000 nM
   TI
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CP0198404
 Compound Info 
4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-3-ylpropyl]cyclohexane-1-carboxamide
   Show/Hide
 C27H39F2N5OS  1
1
CC50 = 674.8 nM
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CP0198517
 Compound Info 
3-(1,4-dioxonaphthalen-2-yl)sulfanylpropanoic acid
   Show/Hide
 C13H10O4S  1
1
IC50 = 23400 nM
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CP0201640
 Compound Info 
2-(2-methoxyethylsulfanyl)-3-methylnaphthalene-1,4-dione
   Show/Hide
 C14H14O3S  1
1
IC50 = 6200 nM
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CP0211683
 Compound Info 
2-chloro-6-cyano-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
   Show/Hide
 C24H31ClN6O3S  1
1
CC50 > 38500 nM
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   TS
CP0229013
 Compound Info 
(1E,4E)-1,5-bis[4-hydroxy-3-methoxy-5-(3-methylbut-2-enyl)phenyl]penta-1,4-dien-3-one
   Show/Hide
 C29H34O5  1
1
IC50 > 50000 nM
   TI
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CP0248779
 Compound Info 
2,6-dichloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methyl-1-oxidopyridin-1-ium-3-carboxamide
   Show/Hide
 C23H31Cl2N5O4S  1
1
CC50 > 38500 nM
   TI
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CP0255268
 Compound Info 
5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methylpropyl)-6-(naphthalen-1-ylmethyl)-1H,2H,3H,4H,6H-pyrrolo[3,4-d]pyrimidine-2,4-dione
   Show/Hide
 C25H29N3O3S  1
1
IC50 = 2.455 nM
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   TS
CP0256763
 Compound Info 
2,6-dichloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
   Show/Hide
 C23H31Cl2N5O3S  1
1
CC50 > 37800 nM
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   TS
CP0270180
 Compound Info 
N-[(3R)-3-[4-[acetyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-6-chloro-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
 C24H33ClN4O2S  1
1
CC50 > 42000 nM
   TI
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   TS
CP0270340
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[pyridin-3-ylcarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
 C28H35ClN6O2S  1
1
CC50 > 32378 nM
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   TS
CP0278310
 Compound Info 
6-chloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
 C24H34ClN5O3S  1
1
CC50 > 35200 nM
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CP0283663
 Compound Info 
4-[[[[1-[(2R)-4-[(6-chloro-2,4-dimethylpyridine-3-carbonyl)amino]butan-2-yl]piperidin-4-yl]-(thiophen-3-ylmethyl)carbamoyl]amino]methyl]benzoic acid
   Show/Hide
 C31H38ClN5O4S  1
1
CC50 > 32200 nM
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CP0285119
 Compound Info 
N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
   Show/Hide
 C30H40N6O2  1
1
CC50 > 38300 nM
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CP0308241
 Compound Info 
1-allyl-1-((1R,3R,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)-3-(4-(trifluoromethyl)benzyl)urea
   Show/Hide
 C36H44F4N4O3  1
1
CC50 = 102700 nM
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CP0364042
 Compound Info 
ethyl (4S)-6-bromo-4-(1H-indazole-7-carbonylamino)spiro[3,4-dihydrochromene-2,4'-piperidine]-1'-carboxylate
   Show/Hide
 C24H25BrN4O4  1
1
CC50 > 10000 nM
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CP0372492
 Compound Info 
6-fluoro-N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
 C31H40FN5O2  1
1
CC50 > 36300 nM
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CP0377212
 Compound Info 
4-((3-allyl-3-((1R,3R,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)ureido)methyl)-N-methylbenzenesulfonamide
   Show/Hide
 C36H48FN5O5S  1
1
CC50 = 50000 nM
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CP0377885
 Compound Info 
2-amino-9-[(2R,5S)-4-fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-1H-purin-6-one
   Show/Hide
 C10H10FN5O3  1
1
IC50 > 100000 nM
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CP0384188
 Compound Info 
5-(2,5-dihydropyrrole-1-carbonyl)-3-methyl-1-(2-methylpropyl)-6-[[2-(trifluoromethyl)phenyl]methyl]thieno[2,3-d]pyrimidine-2,4-dione
   Show/Hide
 C24H24F3N3O3S  1
1
IC50 = 12.02 nM
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CP0384516
 Compound Info 
2-amino-9-[(2S,5S)-4-fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-1H-purin-6-one
   Show/Hide
 C10H10FN5O3  1
1
IC50 = 17400 nM
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CP0388035
 Compound Info 
N-[3-[4-[N-benzyl-4-(dimethylcarbamoyl)anilino]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
   Show/Hide
 C31H37Cl2N5O2  1
1
CC50 > 30000 nM
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CP0390755
 Compound Info 
N-[3-[4-[5-(3-bromophenyl)-3-cyclohexyl-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
   Show/Hide
 C31H43BrN6O2  1
1
CC50 > 32699 nM
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CP0401510
 Compound Info 
(1-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)piperidin-4-yl)(4-fluorophenyl)methanone
   Show/Hide
 C27H27FN2O3  1
1
ED50 = 9000 nM
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CP0401679
 Compound Info 
[(2S,5R)-5-(6-aminopurin-9-yl)-3,3-difluorooxolan-2-yl]methanol
   Show/Hide
 C10H11F2N5O2  1
1
IC50 > 100000 nM
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CP0402442
 Compound Info 
5-(cyclopentylsulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide
   Show/Hide
 C18H17F3N2O3S  1
1
CC50 = 15600 nM
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CP0411900
 Compound Info 
1-Isobutyl-3-methyl-6-naphthalen-1-ylmethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione
   Show/Hide
 C22H23N3O2  1
1
IC50 = 56.23 nM
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CP0413858
 Compound Info 
4-[5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzoic acid
   Show/Hide
 C32H36N4O5  1
1
CC50 > 27300 nM
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CP0416082
 Compound Info 
6-(4-methylsulfonylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)sulfonylimidazo[1,2-b]pyridazine
   Show/Hide
 C22H22N6O4S2  1
1
IC50 > 30000 nM
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CP0416704
 Compound Info 
trisodium;[[(E)-4-hydroxy-3-methylbut-2-enoxy]-oxidophosphoryl] phosphate
   Show/Hide
 C5H9Na3O8P2  1
1
EC50 = 0.5 nM
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CP0417344
 Compound Info 
5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one
   Show/Hide
 C21H17NO3S  1
1
EC50 = 2500 nM
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CP0417935
 Compound Info 
3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]propanamide
   Show/Hide
 C60H81N9O7  1
1
IC50 = 55000 nM
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CP0417937
 Compound Info 
3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]hexyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]propanamide
   Show/Hide
 C54H77N9O6  1
1
IC50 = 80000 nM
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CP0418421
 Compound Info 
4-[4-[3-(4-chlorophenyl)-2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-3,4-dihydropyrazol-5-yl]phenyl]morpholine
   Show/Hide
 C28H24ClFN4OS  1
1
IC50 > 300000 nM
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CP0424262
 Compound Info 
N-(2-methylpropyl)-5-(1-methylsulfonylpiperidin-4-yl)oxy-N-[[2-(trifluoromethyl)phenyl]methyl]pyridine-2-sulfonamide
   Show/Hide
 C23H30F3N3O5S2  1
1
EC50 > 20000 nM
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CP0424265
 Compound Info 
N-(2-methylpropyl)-4-[(1-methylsulfonylpiperidin-4-yl)amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzenesulfonamide
   Show/Hide
 C24H32F3N3O4S2  1
1
EC50 > 20000 nM
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CP0428242
 Compound Info 
N-[(3R)-3-[4-[N-[(6-cyanopyridin-2-yl)methyl]-4-methoxyanilino]piperidin-1-yl]butyl]-6-fluoro-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
 C31H37FN6O2  1
1
CC50 > 35800 nM
   TI
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CP0429523
 Compound Info 
5-(cyclopentylsulfonylamino)-N-(3,4-difluorophenyl)-2-fluorobenzamide
   Show/Hide
 C18H17F3N2O3S  1
1
CC50 > 100000 nM
   TI
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CP0429968
 Compound Info 
5-[3-(4-pyridin-2-ylpiperazin-1-yl)sulfonylimidazo[1,2-b]pyridazin-6-yl]-3-(trifluoromethyl)pyridin-2-amine
   Show/Hide
 C21H19F3N8O2S  1
1
IC50 > 30000 nM
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CP0431208
 Compound Info 
2-chloro-N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
   Show/Hide
 C30H38ClN5O2  1
1
CC50 > 37700 nM
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CP0433030
 Compound Info 
N-[3-[4-(N-benzyl-4-cyanoanilino)piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
   Show/Hide
 C29H31Cl2N5O  1
1
CC50 = 9700 nM
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CP0433791
 Compound Info 
3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]propanamide
   Show/Hide
 C48H63N7O6  1
1
IC50 = 67000 nM
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CP0438392
 Compound Info 
1-[(2R,5S)-4,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
   Show/Hide
 C10H12F2N2O4  1
1
IC50 > 100000 nM
   TI
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CP0438430
 Compound Info 
2-amino-9-[(2S,5S)-4,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
   Show/Hide
 C10H11F2N5O3  1
1
IC50 > 100000 nM
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CP0446354
 Compound Info 
1-[6-(4-methylsulfonylphenyl)imidazo[1,2-b]pyridazin-3-yl]sulfonyl-4-phenylpiperidine-4-carbonitrile
   Show/Hide
 C25H23N5O4S2  1
1
IC50 > 30000 nM
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CP0460765
 Compound Info 
3,5-dichloro-N-(3-(4-((6-methylpyridin-2-yloxy)(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C29H31Cl2F3N4O2  1
1
CC50 = 6700 nM
   TI
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   TS
CP0462246
 Compound Info 
4-[5-[[4-[(5R)-5-(3-fluorophenyl)-3-(oxan-4-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]methyl]-6-methylpyridin-2-yl]oxybenzoic acid
   Show/Hide
 C33H37FN4O5  1
1
CC50 > 33900 nM
   TI
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   TS
CP0463516
 Compound Info 
N-[3-[4-(N-benzyl-4-bromoanilino)piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
   Show/Hide
 C28H31BrCl2N4O  1
1
CC50 = 4280 nM
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   TS
CP0464755
 Compound Info 
N-[3-[4-(7-bromo-1H-2,3-benzoxazin-4-yl)piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
   Show/Hide
 C23H25BrCl2N4O2  1
1
CC50 = 185100 nM
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   TS
CP0466185
 Compound Info 
3,5-dichloro-N-(3-(4-(2-(4-(trifluoromethyl)phenyl)benzo[d][1,3]dioxol-2-yl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C29H28Cl2F3N3O3  1
1
CC50 = 7800 nM
   TI
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   TS
CP0470960
 Compound Info 
9-[(2S,5S)-4,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
   Show/Hide
 C10H10F2N4O3  1
1
IC50 > 100000 nM
   TI
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   TS
CP0472079
 Compound Info 
propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-4-bromo-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
   Show/Hide
 C21H26BrFN3O9P  1
1
CC50 > 100000 nM
   TI
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   TS
CP0479105
 Compound Info 
3,5-dichloro-N-(3-(4-((4-methylpyridin-2-yloxy)(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C29H31Cl2F3N4O2  1
1
CC50 = 33600 nM
   TI
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   TS
CP0484960
 Compound Info 
3,5-dichloro-N-(3-(4-((3-fluorophenoxy)(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C29H29Cl2F4N3O2  1
1
CC50 = 5400 nM
   TI
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   TS
CP0486561
 Compound Info 
3,5-dichloro-N-(3-(4-((2-cyanophenoxy)(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C30H29Cl2F3N4O2  1
1
CC50 = 17000 nM
   TI
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   TS
CP0486565
 Compound Info 
N-[3-[4-[(4-bromophenyl)-(3-methylpyridin-2-yl)oxymethyl]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
   Show/Hide
 C28H31BrCl2N4O2  1
1
CC50 = 32100 nM
   TI
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   TS
CP0490964
 Compound Info 
3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]-3-(4-hydroxyphenyl)propyl]amino]propanamide
   Show/Hide
 C51H70N8O6  1
1
IC50 = 56000 nM
   TI
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   TS
CP0492499
 Compound Info 
6-fluoro-N-[(3R)-3-[4-[4-(2-methoxyethoxy)-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
 C33H44FN5O3  1
1
CC50 > 32700 nM
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   TS
CP0495878
 Compound Info 
1-[(2S,5S)-4,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
   Show/Hide
 C10H12F2N2O4  1
1
IC50 > 100000 nM
   TI
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   LO
   TS
CP0499450
 Compound Info 
3,5-dichloro-N-[3-[4-[N-[(3-cyanophenyl)methyl]-4-(trifluoromethoxy)anilino]piperidin-1-yl]butyl]pyridine-4-carboxamide
   Show/Hide
 C30H30Cl2F3N5O2  1
1
CC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0501376
 Compound Info 
(E)-N-(2-(1-(4-((4-bromophenyl)(ethoxyimino)methyl)piperidin-1-yl)cyclopropyl)ethyl)-3,5-dichloroisonicotinamide
   Show/Hide
 C25H29BrCl2N4O2  1
1
CC50 = 33000 nM
   TI
   LI
   LO
   TS
CP0503385
 Compound Info 
3,5-dichloro-N-(3-(4-((pyridin-2-yloxy)(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C28H29Cl2F3N4O2  1
1
CC50 = 34100 nM
   TI
   LI
   LO
   TS
CP0505365
 Compound Info 
N-[3-[4-[(4-bromophenyl)-pyridin-2-yloxymethyl]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
   Show/Hide
 C27H29BrCl2N4O2  1
1
CC50 = 33700 nM
   TI
   LI
   LO
   TS
CP0505871
 Compound Info 
4-amino-1-[(2S,5S)-4,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
   Show/Hide
 C9H11F2N3O3  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0510700
 Compound Info 
methyl 4-[benzyl-[1-[4-[(3,5-dichloropyridine-4-carbonyl)amino]butan-2-yl]piperidin-4-yl]amino]benzoate
   Show/Hide
 C30H34Cl2N4O3  1
1
CC50 = 21400 nM
   TI
   LI
   LO
   TS
CP0511055
 Compound Info 
3,5-dichloro-N-(3-(4-(phenoxy(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C29H30Cl2F3N3O2  1
1
CC50 = 6800 nM
   TI
   LI
   LO
   TS
CP0511355
 Compound Info 
3,5-dichloro-N-(3-(4-((3-chlorophenoxy)(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C29H29Cl3F3N3O2  1
1
CC50 = 8100 nM
   TI
   LI
   LO
   TS
CP0513676
 Compound Info 
3,5-dichloro-N-(3-(4-((4-chloropyridin-2-yloxy)(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C28H28Cl3F3N4O2  1
1
CC50 = 4260 nM
   TI
   LI
   LO
   TS
CP0519799
 Compound Info 
4-phenyl-1-(6-pyridin-3-ylimidazo[1,2-b]pyridazin-3-yl)sulfonylpiperidine-4-carbonitrile
   Show/Hide
 C23H20N6O2S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0523495
 Compound Info 
6-chloro-N-[(3-methoxyphenyl)methyl]imidazo[1,2-b]pyridazine-3-sulfonamide
   Show/Hide
 C14H13ClN4O3S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0523504
 Compound Info 
6-(6-methoxypyridin-3-yl)-3-(4-pyridin-2-ylpiperazin-1-yl)sulfonylimidazo[1,2-b]pyridazine
   Show/Hide
 C21H21N7O3S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0523508
 Compound Info 
N-(oxolan-2-ylmethyl)-6-[5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-b]pyridazine-3-sulfonamide
   Show/Hide
 C17H16F3N5O3S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0523509
 Compound Info 
3-(4-ethylpiperazin-1-yl)sulfonyl-6-[5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-b]pyridazine
   Show/Hide
 C18H19F3N6O2S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0524507
 Compound Info 
(E)-N-(3-(4-((4-bromophenyl)(ethoxyimino)methyl)piperidin-1-yl)butyl)-3,5-dichloroisonicotinamide
   Show/Hide
 C24H29BrCl2N4O2  1
1
CC50 = 33800 nM
   TI
   LI
   LO
   TS
CP0524696
 Compound Info 
6-cyano-N-[(3R)-3-[4-[N-[(6-cyanopyridin-2-yl)methyl]-4-methoxyanilino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
 C32H37N7O2  1
1
CC50 > 36300 nM
   TI
   LI
   LO
   TS
CP0530022
 Compound Info 
N-[3-[4-[(4-bromophenyl)-hydroxymethyl]piperidin-1-yl]butyl]-3,5-dichloropyridine-4-carboxamide
   Show/Hide
 C22H26BrCl2N3O2  1
1
CC50 = 198300 nM
   TI
   LI
   LO
   TS
CP0531452
 Compound Info 
6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-2-oxo-5-phenyl-3-(pyridin-2-ylmethyl)imidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
 C32H39ClN6O2  1
1
CC50 > 34237 nM
   TI
   LI
   LO
   TS
CP0531516
 Compound Info 
2-amino-9-[(2R,5S)-4,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
   Show/Hide
 C10H11F2N5O3  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0532364
 Compound Info 
1-[(2S,5S)-4-fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione
   Show/Hide
 C10H11FN2O4  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0533327
 Compound Info 
4,6-dimethyl-N-[(3R)-3-[4-[N-[(4-methylpyridin-3-yl)methyl]-4-methylsulfinylanilino]piperidin-1-yl]butyl]pyrimidine-5-carboxamide
   Show/Hide
 C30H40N6O2S  1
1
CC50 > 32400 nM
   TI
   LI
   LO
   TS
CP0536452
 Compound Info 
1,5-bis[(1S)-5-hydroxy-1-methyl-1,2-dihydrobenzo[e]indol-3-yl]pentane-1,5-dione
   Show/Hide
 C31H30N2O4  1
1
IC50 > 80000 nM
   TI
   LI
   LO
   TS
CP0538732
 Compound Info 
5-(cyclohexylsulfonylamino)-N-(3,4-difluorophenyl)-2-fluorobenzamide
   Show/Hide
 C19H19F3N2O3S  1
1
CC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0540420
 Compound Info 
6-chloro-N-[(3R)-3-[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
 C32H44ClN5O2  1
1
CC50 = 33900 nM
   TI
   LI
   LO
   TS
CP0541132
 Compound Info 
N-[(3-methoxyphenyl)methyl]-6-(6-methoxypyridin-3-yl)imidazo[1,2-b]pyridazine-3-sulfonamide
   Show/Hide
 C20H19N5O4S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0546988
 Compound Info 
3-(4-benzylpiperazin-1-yl)sulfonyl-6-pyridin-3-ylimidazo[1,2-b]pyridazine
   Show/Hide
 C22H22N6O2S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0546989
 Compound Info 
6-chloro-3-(4-ethylpiperazin-1-yl)sulfonylimidazo[1,2-b]pyridazine
   Show/Hide
 C12H16ClN5O2S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0554743
 Compound Info 
3,5-dichloro-N-(3-(4-((6-cyanopyridin-2-yloxy)(4-(trifluoromethyl)phenyl)methyl)piperidin-1-yl)butyl)isonicotinamide
   Show/Hide
 C29H28Cl2F3N5O2  1
1
CC50 = 15700 nM
   TI
   LI
   LO
   TS
CP0564788
 Compound Info 
3-(4-ethylpiperazin-1-yl)sulfonyl-6-pyridin-3-ylimidazo[1,2-b]pyridazine
   Show/Hide
 C17H20N6O2S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0564789
 Compound Info 
1-(6-chloroimidazo[1,2-b]pyridazin-3-yl)sulfonyl-4-phenylpiperidine-4-carbonitrile
   Show/Hide
 C18H16ClN5O2S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0564800
 Compound Info 
6-(5-fluoropyridin-3-yl)-N-(oxolan-2-ylmethyl)imidazo[1,2-b]pyridazine-3-sulfonamide
   Show/Hide
 C16H16FN5O3S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0569161
 Compound Info 
6-(4-methoxyphenyl)-N-(oxolan-2-ylmethyl)imidazo[1,2-b]pyridazine-3-sulfonamide
   Show/Hide
 C18H20N4O4S  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0569164
 Compound Info 
6-(4-methylsulfonylphenyl)-N-(oxolan-2-ylmethyl)imidazo[1,2-b]pyridazine-3-sulfonamide
   Show/Hide
 C18H20N4O5S2  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0569167
 Compound Info 
3-(4-ethylpiperazin-1-yl)sulfonyl-6-(4-methylsulfonylphenyl)imidazo[1,2-b]pyridazine
   Show/Hide
 C19H23N5O4S2  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0692447
 Compound Info 
Limonin
   Show/Hide
 C26H30O8  1
1
CC50 = 960448.015 nM
   TI
   LI
   LO
   TS
CP0852034
 Compound Info 
1',1'',1''',1'''',1''''',1'''''',1''''''',1''''''''-(5,5',5'',5'''-(1',1'',1''',1''''-(5,5'-(4,4'-bipyridine-1,1'-diium-1,1'-diyl)bis(benzene-5,3,1-triyl))tetrakis(methylene)tetrakis(4',4''-bipyridine-1,1'-diium-1',1'-diyl))tetrakis(methylene)tetrakis(benzene-5,3,1-triyl))octakis(methylene)octakis(1-(3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propyl)-4',4''-bipyridine-1,1'-diium)hexafluorophosphate (V)
   Show/Hide
 C246H242F156N42O16P26  1
1
CC50 = 2560.186791 nM
   TI
   LI
   LO
   TS
CP0852846
 Compound Info 
(+)-1-(4-Fluoro-5-hydroxymethyl-2,5-dihydro-furan-2-yl)-4-hydroxy-1H-pyrimidin-2-one
   Show/Hide
 C9H9FN2O4  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0860688
 Compound Info 
1',1'',1''',1'''',1''''',1''''''-(5,5',5''-(1',1'',1'''-(benzene-1,3,5-triyltris(methylene))tris(4,4'-bipyridine-1,1'-diium-1',1-diyl))tris(methylene)tris(benzene-5,3,1-triyl))hexakis(methylene)hexakis(1-ethyl-4,4'-bipyridine-1,1'-diium)hexafluorophosphate (V)
   Show/Hide
 C138H138F108N18P18  1
1
CC50 = 4293.632972 nM
   TI
   LI
   LO
   TS
CP0866102
 Compound Info 
1',1'',1''',1'''',1''''',1''''''-(5,5',5''-(1',1'',1'''-(benzene-1,3,5-triyltris(methylene))tris(4,4'-bipyridine-1,1'-diium-1',1-diyl))tris(methylene)tris(benzene-5,3,1-triyl))hexakis(methylene)hexakis(1-(3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propyl)-4,4'-bipyridine-1,1'-diium)hexafluorophosphate (V)
   Show/Hide
 C174H174F108N30O12P18  1
1
CC50 = 3645.098618 nM
   TI
   LI
   LO
   TS
CP0866103
 Compound Info 
1',1'',1''',1'''',1''''',1'''''',1''''''',1'''''''',1''''''''',1'''''''''',1''''''''''',1''''''''''''-(5,5',5'',5''',5'''',5'''''-(1',1'',1''',1'''',1''''',1''''''-(5,5',5''-(1',1'',1'''-(benzene-1,3,5-triyltris(methylene))tris(4,4'-bipyridine-1,1'-diium-1',1-diyl))tris(methylene)tris(benzene-5,3,1-triyl))hexakis(methylene)hexakis(4,4'-bipyridine-1,1'-diium-1',1-diyl))hexakis(methylene)hexakis(benzene-5,3,1-triyl))dodecakis(methylene)dodecakis(1-ethyl-4,4'-bipyridine-1,1'-diium)hexafluorophosphate (V)
   Show/Hide
 C324H318F252N42P42  1
1
CC50 = 1836.748001 nM
   TI
   LI
   LO
   TS
CP0900117
 Compound Info 
(E)-3-(2-(4-((4-bromophenyl)(ethoxyimino)methyl)piperidin-1-yl)propylcarbamoyl)-2,4-dimethylpyridine 1-oxide
   Show/Hide
 C25H33BrN4O3  1
1
CC50 = 182100 nM
   TI
   LI
   LO
   TS
CP0910882
 Compound Info 
(E)-3-(3-(4-((4-bromophenyl)(ethoxyimino)methyl)piperidin-1-yl)butylcarbamoyl)-2,4-dimethylpyridine 1-oxide
   Show/Hide
 C26H35BrN4O3  1
1
CC50 > 177900 nM
   TI
   LI
   LO
   TS
CP0921817
 Compound Info 
(+)-4-Amino-5-fluoro-1-(4-fluoro-5-hydroxymethyl-2,5-dihydro-furan-2-yl)-1H-pyrimidin-2-one
   Show/Hide
 C9H9F2N3O3  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0935650
 Compound Info 
(E)-3-((3-(4-((4-bromophenyl)(ethoxyimino)methyl)piperidin-1-yl)butyl)(methyl)carbamoyl)-2,4-dimethylpyridine 1-oxide
   Show/Hide
 C27H37BrN4O3  1
1
CC50 > 182700 nM
   TI
   LI
   LO
   TS
CP0957158
 Compound Info 
Schering C
   Show/Hide
 C28H37BrN4O3  1
1
CC50 > 1600 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Peripheral blood)
Cell Line Name Organism Disease
SET-2
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
Mono-Mac-6
 Cell Line Info 
Homo sapiens (Human) Adult acute monocytic leukemia
HL-60
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-13
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
OCI-AML-2
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL-60/ADR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-14
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MDR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MRP
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
NALM-6
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
MOLT-4
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
MOLT-4/CCR5
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
Karpas-299
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
M-07e
 Cell Line Info 
Homo sapiens (Human) Childhood acute megakaryoblastic leukemia
THP-1
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
MV4-11
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Blue ISG
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-ASC-GFP
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
PMNL
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Xblue
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
SEM
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SEMK2
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Reh
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-CEM
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF/VCR1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB100
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB500
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-SS
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
HPB-ALL
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-SB
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-T4
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
J-Lat 10.6
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
12D7-MDR1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
MDR CCRF vcr1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
FGS7 Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
EoL-1
 Cell Line Info 
Homo sapiens (Human) Chronic eosinophilic leukemia, not otherwise specified
CII
 Cell Line Info 
Homo sapiens (Human) Chronic lymphocytic leukemia
Ku812
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
Ri-1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
Daudi
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HEL
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
UKE-1
 Cell Line Info 
Homo sapiens (Human) Essential thrombocythemia
L-1236
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
Granta-519
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
JeKo-1
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
Mino
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
HMC-1
 Cell Line Info 
Homo sapiens (Human) Mast cell leukemia
NK-92
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
NK
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-2
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
U266B1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-18
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.S
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.R
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
RPMI-8226/Dox40
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
HuT 78
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
H9
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
CREM010i-SS9-1
 Cell Line Info 
Homo sapiens (Human) Sickle cell disease
RBL-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
RBL-2H3
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
LCL Orang Asli K28
 Cell Line Info 
Homo sapiens (Human) -
JY
 Cell Line Info 
Homo sapiens (Human) -
C.M.L.
 Cell Line Info 
Homo sapiens (Human) -
BON
 Cell Line Info 
Homo sapiens (Human) -
LCL 721
 Cell Line Info 
Homo sapiens (Human) -