Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R,5S)-7-cyclohexyl-1-[[6-(4-fluorophenyl)pyridin-3-yl]methyl]-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
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 PubChem ID
CID: 168268991
Canonical SMILES
O[C@H]1CN(Cc2ccc(nc2)-c2ccc(F)cc2)[C@@]2(CCN(C3CCCCC3)C2=O)C1
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Compound Formula C25H30FN3O2
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 37 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 80 nM