| Compound ID |
Compound Name |
Compound Formula |
|
CP0233638
|
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
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|
C17H22N4O2
|
1
|
| 1 |
Activity = 4.478514 nM
|
|
|
|
CP0229826
|
6-amino-9-benzyl-2-(2-methoxyethoxy)-7H-purin-8(9H)-one
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|
C15H17N5O3
|
1
|
| 1 |
Activity = 4.57933 nM
|
|
|
|
CP0859648
|
6-amino-2-[(1S)-1-methylbutoxy]-9-[5-(4-piperidyl)pentyl]-7H-purin-8-one Hydrochloride
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|
C20H35ClN6O2
|
1
|
| 1 |
Activity = 6.187499 nM
|
|
|
|
CP0402140
|
6-amino-2-(2-methoxyethoxy)-9-(piperidin-4-ylmethyl)-7H-purin-8-one;hydrochloride
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|
C14H23ClN6O3
|
1
|
| 1 |
Activity = 6.24251 nM
|
|
|
|
CP0437656
|
6-amino-9-[[1-(2-aminoethyl)piperidin-4-yl]methyl]-2-butoxy-7H-purin-8-one;hydrochloride
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|
C17H30ClN7O2
|
1
|
| 1 |
Activity = 7.613832 nM
|
|
|
|
CP0870709
|
6-amino-9-[[1-(2-aminoethyl)-4-piperidyl]methyl]-2-[(1S)-1-methylbutoxy]-7H-purin-8-one Hydrochloride
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|
C18H32ClN7O2
|
1
|
| 1 |
Activity = 10.665539 nM
|
|
|
|
CP0859647
|
4-(5-(6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)pentyl)piperidinium chloride
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|
C19H33ClN6O2
|
1
|
| 1 |
Activity = 11.327699 nM
|
|
|
|
CP0859644
|
6-amino-9-[[1-(2-hydroxyethyl)-4-piperidyl]methyl]-2-[(1S)-1-methylbutoxy]-7H-purin-8-one Hydrochloride
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|
C18H31ClN6O3
|
1
|
| 1 |
Activity = 11.437798 nM
|
|
|
|
CP0402138
|
6-amino-2-butoxy-9-[[1-(2-hydroxyethyl)piperidin-4-yl]methyl]-7H-purin-8-one;hydrochloride
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|
C17H29ClN6O3
|
1
|
| 1 |
Activity = 11.800654 nM
|
|
|
|
CP0859645
|
6-amino-2-[(1S)-1-methylbutoxy]-9-(4-piperidylmethyl)-7H-purin-8-one Hydrochloride
Show/Hide
|
C16H27ClN6O2
|
1
|
| 1 |
Activity = 14.756397 nM
|
|
|
|
CP0859646
|
4-((6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)methyl)piperidinium chloride
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|
C15H25ClN6O2
|
1
|
| 1 |
Activity = 16.530292 nM
|
|
|
|
CP0859661
|
6-amino-2-[(1R)-1-methylbutoxy]-9-(4-piperidylmethyl)-7H-purin-8-one Hydrochloride
Show/Hide
|
C16H27ClN6O2
|
1
|
| 1 |
Activity = 16.743509 nM
|
|
|
|
CP0516848
|
6-amino-2-(butylamino)-9-(piperidin-4-ylmethyl)-7H-purin-8-one;hydrochloride
Show/Hide
|
C15H26ClN7O
|
1
|
| 1 |
Activity = 16.812319 nM
|
|
|
|
CP0964164
|
5-cyclopropyl-6-(3-fluoro-2-methylpyridin-4-yl)-N-((3S,4S)-3-fluoropiperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C21H23F2N5
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0528720
|
5-cyclopropyl-6-(3-fluoro-2-methylpyridin-4-yl)-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
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|
C22H26FN5
|
1
|
| 1 |
IC50 = 0.39 nM
|
|
|
|
CP0424067
|
8-[2-[(3S,4S)-3-fluoropiperidin-4-yl]-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
Show/Hide
|
C21H20F4N4O
|
1
|
| 1 |
IC50 = 0.62 nM
|
|
|
|
CP0571523
|
6-(3-fluoro-2-methylpyridin-4-yl)-5-methoxy-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C20H24FN5O
|
1
|
| 1 |
IC50 = 0.67 nM
|
|
|
|
CP0544570
|
6-(3-fluoro-2-methylpyridin-4-yl)-5-methyl-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C20H24FN5
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0950854
|
2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperidin-4-yl)-1H-indole
Show/Hide
|
C23H29N3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0575755
|
[6-(2,6-dimethylpyridin-4-yl)-5-methoxy-1H-indazol-3-yl]-(4-methylpiperazin-1-yl)methanone
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|
C21H25N5O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0571522
|
5-methoxy-N-(1-methylpiperidin-4-yl)-6-pyridin-4-yl-1H-indazol-3-amine
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|
C19H23N5O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0388424
|
2-[4-[2-(3,4-dimethoxyphenyl)-3-propan-2-yl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
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|
C27H37N3O2
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0941521
|
5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-N-((3R,4R)-3-fluoropiperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C22H26FN5
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0966188
|
5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-N-((3S,4S)-3-fluoropiperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C22H26FN5
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0575034
|
5-methoxy-6-(2-methoxypyridin-4-yl)-N-(1-methylpiperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C20H25N5O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0409314
|
1,4-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
Show/Hide
|
C20H24N4O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0525568
|
1,6-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
Show/Hide
|
C20H24N4O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0424056
|
1,3-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
Show/Hide
|
C20H24N4O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0409312
|
1-methyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
Show/Hide
|
C19H22N4O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0498368
|
(5-methoxy-6-pyridin-4-yl-1H-indazol-3-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0531875
|
5-[2-(4-cyclobutylpiperazin-1-yl)quinazolin-6-yl]-1-methylpyridin-2-one
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0528718
|
5-methoxy-6-pyridin-4-yl-1H-indole
Show/Hide
|
C14H12N2O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0424053
|
1-methyl-5-[8-methyl-2-(4-propan-2-ylpiperazin-1-yl)quinazolin-6-yl]pyridin-2-one
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0528719
|
[6-(3-fluoro-2-methylpyridin-4-yl)-5-methoxy-1H-indazol-3-yl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C20H22FN5O2
|
1
|
| 1 |
IC50 > 980 nM
|
|
|
