Brief Information of the Compound and Protein
Compound Name
(5-methoxy-6-pyridin-4-yl-1H-indazol-3-yl)-(4-methylpiperazin-1-yl)methanone
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Canonical SMILES
COc1cc2c(n[nH]c2cc1-c1ccncc1)C(=O)N1CCN(C)CC1
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Compound Formula C19H21N5O2
Compound Structure
Protein Name
Toll-like receptor 7
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NYK1
Gene Name
TLR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS