Brief Information of the Compound and Protein
Compound Name
4-((6-amino-2-butoxy-8-oxo-7H-purin-9(8H)-yl)methyl)piperidinium chloride
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PubChem ID
CID: 67607123
Canonical SMILES
CCCCOc1nc(N)c2[nH]c(=O)n(CC3CCNCC3)c2n1.Cl
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Compound Formula C15H25ClN6O2
Compound Structure
Protein Name
Toll-like receptor 7
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NYK1
Gene Name
TLR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 3950 nM
   TI
   LI
   LO
   TS
2
EC50 = 19800 nM
   TI
   LI
   LO
   TS
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
Activity = 16.530292 nM
   TI
   LI
   LO
   TS