Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R)-1'-(1-pyridin-4-ylcyclopropanecarbonyl)spiro[2-benzofuran-3,3'-pyrrolidine]-1-one
    Show/Hide
 PubChem ID
CID: 66662056
Canonical SMILES
O=C(N1CC[C@@]2(C1)OC(=O)c1ccccc21)C1(CC1)c1ccncc1
    Show/Hide
Compound Formula C20H18N2O3
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 117 nM