Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[5-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]pyridin-2-yl]benzonitrile
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 PubChem ID
CID: 168272545
Canonical SMILES
O[C@H]1CN(Cc2ccc(nc2)-c2ccc(cc2)C#N)[C@@]2(CCN(C3CCCCC3)C2=O)C1
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Compound Formula C26H30N4O2
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18 nM