General Information of the Cell Line
Cell Line ID
CL000082
Cell Line Name
HEL
Synonyms
Hel
GM06141
GM06141B
Human ErythroLeukemia
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0001
Tissue Information
Peripheral blood
Disease
Erythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00897, Eag homolog
 Protein Info 
Compound ID Compound Name Compound Formula
CP0387547
 Compound Info 
(S)-4-(2,5-difluorophenyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2-phenyl-2H-pyrrole-1(5H)-carboxamide
   Show/Hide
C24H27F2N3O
  1
1
IC50 = 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0452185
 Compound Info 
(2S)-4-(2,5-difluorophenyl)-N-(1-(2-fluoroethyl)piperidin-4-yl)-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C26H30F3N3O2
  1
1
IC50 = 13800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0495651
 Compound Info 
(2S)-4-(2,5-Difluorophenyl)-2-(hydroxymethyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C25H29F2N3O2
  1
1
IC50 = 14600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0468453
 Compound Info 
(2S)-N-(1-cyclopropylpiperidin-4-yl)-4-(2,5-difluorophenyl)-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C27H31F2N3O2
  1
1
IC50 = 15200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0277177
 Compound Info 
(S)-2-((R)-3-amino-4,4-difluorobutyl)-4-(2,5-difluorophenyl)-N,N-dimethyl-2-phenyl-2H-pyrrole-1(5H)-carboxamide
   Show/Hide
C23H25F4N3O
  1
1
IC50 = 15900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440516
 Compound Info 
(S)-4-(2,5-difluorophenyl)-2-(hydroxymethyl)-N-methyl-2-phenyl-N-(piperidin-4-yl)-2,5dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C24H27F2N3O2
  1
1
IC50 = 19200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0201232
 Compound Info 
(2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
   Show/Hide
C25H28F3N3O2
  1
1
IC50 = 20500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0480241
 Compound Info 
(S)-4-(2,5-difluorophenyl)-N-((3S,4S)-3-fluoro-1-methylpiperidin-4-yl)-2-(hydroxymethyl)-N-methyl-2-phenyl-2H-pyrrole-1(5H)-carboxamide
   Show/Hide
C25H28F3N3O2
  1
1
IC50 = 36900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01431, Melanocortin receptor 4
 Protein Info 
Protein ID: PT01528, Melanocortin receptor 5
 Protein Info 
Protein ID: PT02259, Neuropeptide Y receptor type 1
 Protein Info 
Protein ID: PT02279, Prostacyclin receptor
 Protein Info 
Protein ID: PT01214, Tyrosine-protein kinase JAK2
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0002230
 Compound Info 
4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
   Show/Hide
 C28H22F3N7O  1
1
GI50 = 3900 nM
   TI
   LI
   LO
   TS
CP0002778
 Compound Info 
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
   Show/Hide
 C29H31N7O  1
1
GI50 = 5300 nM
   TI
   LI
   LO
   TS
CP0007430
 Compound Info 
IBRUTINIB
   Show/Hide
 C25H24N6O2  1
1
GI50 = 4000 nM
   TI
   LI
   LO
   TS
CP0014444
 Compound Info 
N-[8-(hydroxyamino)-8-oxooctyl]-1-[4-[[4-[4-(methanesulfonamido)phenyl]pyrimidin-2-yl]amino]phenyl]piperidine-4-carboxamide
   Show/Hide
 C31H41N7O5S  1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0035635
 Compound Info 
(2S,5R)-4-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-5-ethyl-2-morpholinecarboxamide
   Show/Hide
 C25H34N8O2  1
1
IC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0035637
 Compound Info 
1,1-Dimethylethyl{(3R,5R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}methylcarbamate
   Show/Hide
 C24H34N8O2  1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0108938
 Compound Info 
5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
   Show/Hide
 C14H14ClFN8  1
1
GI50 = 390 nM
   TI
   LI
   LO
   TS
CP0112599
 Compound Info 
US8569511, 2
   Show/Hide
 C23H22F2N6O2  1
1
IC50 = 217 nM
   TI
   LI
   LO
   TS
CP0129941
 Compound Info 
2-methoxy-3-methyl-N-[2-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]sulfanyl-1,3-benzothiazol-6-yl]-4-pentan-2-yloxybenzamide
   Show/Hide
 C31H35N3O4S2  1
1
IC50 = 2410 nM
   TI
   LI
   LO
   TS
CP0170186
 Compound Info 
(3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide
   Show/Hide
 C25H34N8O  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0207434
 Compound Info 
1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}carbamate
   Show/Hide
 C22H30N8O2  1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0208472
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
   Show/Hide
 C23H23N5O3S  1
1
GI50 = 120 nM
   TI
   LI
   LO
   TS
CP0290173
 Compound Info 
(2S,5R)-4-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-5-methyl-2-morpholinecarboxamide
   Show/Hide
 C24H32N8O2  1
1
IC50 = 19000 nM
   TI
   LI
   LO
   TS
CP0337540
 Compound Info 
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(oxan-4-yl)pyrazol-4-yl]pyridin-2-amine
   Show/Hide
 C21H21Cl2FN4O2  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0385917
 Compound Info 
2-(3-amino-4-methylanilino)-4-(methylamino)-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrimidine-5-carboxamide
   Show/Hide
 C28H26F3N7O2  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
CP0418611
 Compound Info 
2,3-dimethyl-N-[2-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]sulfanyl-1,3-benzothiazol-6-yl]-4-pentan-2-yloxybenzamide
   Show/Hide
 C31H35N3O3S2  1
1
IC50 = 930 nM
   TI
   LI
   LO
   TS
CP0431676
 Compound Info 
3-[1-(2-chloro-5-fluorophenyl)ethoxy]-5-(4-piperidin-4-ylphenyl)pyridin-2-amine
   Show/Hide
 C24H25ClFN3O  1
1
IC50 = 15964 nM
   TI
   LI
   LO
   TS
CP0493915
 Compound Info 
3-[1-(2-chloro-5-fluorophenyl)ethoxy]-5-(4-piperazin-1-ylphenyl)pyridin-2-amine
   Show/Hide
 C23H24ClFN4O  1
1
IC50 = 19677 nM
   TI
   LI
   LO
   TS
CP0493917
 Compound Info 
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-pyridin-3-ylpyridin-2-amine
   Show/Hide
 C18H14Cl2FN3O  1
1
IC50 = 20076 nM
   TI
   LI
   LO
   TS
CP0562336
 Compound Info 
2-methoxy-N-[2-[2-[[(1S)-1-(4-methoxyphenyl)ethyl]amino]-2-oxoethyl]sulfanyl-1,3-benzothiazol-6-yl]-3-methyl-4-(2-methylpropoxy)benzamide
   Show/Hide
 C31H35N3O5S2  1
1
IC50 = 2050 nM
   TI
   LI
   LO
   TS
CP0568654
 Compound Info 
2-methoxy-N-[2-[2-[[(1S)-1-(3-methoxyphenyl)ethyl]amino]-2-oxoethyl]sulfanyl-1,3-benzothiazol-6-yl]-3-methyl-4-pentan-2-yloxybenzamide
   Show/Hide
 C32H37N3O5S2  1
1
IC50 = 870 nM
   TI
   LI
   LO
   TS
CP0578044
 Compound Info 
3-(1-cyclohexylethoxy)-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
   Show/Hide
 C21H31N5O  1
1
IC50 = 20912 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Peripheral blood)
Cell Line Name Organism Disease
SET-2
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
Mono-Mac-6
 Cell Line Info 
Homo sapiens (Human) Adult acute monocytic leukemia
HL-60
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-13
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
OCI-AML-2
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL-60/ADR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-14
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MDR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MRP
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
NALM-6
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
MOLT-4
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
MOLT-4/CCR5
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
Karpas-299
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
M-07e
 Cell Line Info 
Homo sapiens (Human) Childhood acute megakaryoblastic leukemia
THP-1
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
MV4-11
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Blue ISG
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-ASC-GFP
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
PMNL
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Xblue
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
SEM
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SEMK2
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Reh
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-CEM
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF/VCR1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB100
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB500
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-SS
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
HPB-ALL
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-SB
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-T4
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
J-Lat 10.6
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
12D7-MDR1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
MDR CCRF vcr1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
FGS7 Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
EoL-1
 Cell Line Info 
Homo sapiens (Human) Chronic eosinophilic leukemia, not otherwise specified
CII
 Cell Line Info 
Homo sapiens (Human) Chronic lymphocytic leukemia
Ku812
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
Ri-1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
Daudi
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
UKE-1
 Cell Line Info 
Homo sapiens (Human) Essential thrombocythemia
L-1236
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
Granta-519
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
JeKo-1
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
Mino
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
HMC-1
 Cell Line Info 
Homo sapiens (Human) Mast cell leukemia
NK-92
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
NK
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-2
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
U266B1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-18
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.S
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.R
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
RPMI-8226/Dox40
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
HuT 78
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
H9
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
CREM010i-SS9-1
 Cell Line Info 
Homo sapiens (Human) Sickle cell disease
RBL-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
RBL-2H3
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
LCL Orang Asli K28
 Cell Line Info 
Homo sapiens (Human) -
JY
 Cell Line Info 
Homo sapiens (Human) -
C.M.L.
 Cell Line Info 
Homo sapiens (Human) -
BON
 Cell Line Info 
Homo sapiens (Human) -
PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human) -
LCL 721
 Cell Line Info 
Homo sapiens (Human) -