General Information of the Cell Line
Cell Line ID
CL000278
Cell Line Name
RBL-2H3
Synonyms
RBL2H3
RBL 2H3
RBL.2H3
Category
Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0591
Tissue Information
Peripheral blood
Disease
Rat leukemia (NCIt: C60428)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01827, Adenosine receptor A3
Compound ID Compound Name Compound Formula
CP0388085
(1R,2R,3S,4R,5S)-4-[6-[(3-chlorophenyl)methylamino]-2-hex-1-ynylpurin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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C24H26ClN5O2
 1
1
Ki = 10.7 nM
   TI
   LI
   LO
   TS
CP0395292
(1R,2R,3S,4R,5S)-4-[2-hex-1-ynyl-6-[(3-iodophenyl)methylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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C24H26IN5O2
 1
1
Ki = 26 nM
   TI
   LI
   LO
   TS
CP0388086
(1R,2R,3S,4R,5S)-4-[6-(cyclopropylamino)-2-hex-1-ynylpurin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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C20H25N5O2
 1
1
Ki = 39 nM
   TI
   LI
   LO
   TS
CP0444110
(1R,2R,3S,4R,5S)-4-[6-[(3-fluorophenyl)methylamino]-2-hex-1-ynylpurin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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C24H26FN5O2
 1
1
Ki = 43 nM
   TI
   LI
   LO
   TS
CP0421548
(1R,2R,3S,4R,5S)-4-[6-(cyclopentylamino)-2-hex-1-ynylpurin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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C22H29N5O2
 1
1
Ki = 58 nM
   TI
   LI
   LO
   TS
CP0388087
(1R,2R,3S,4R,5S)-4-[6-[(3-bromophenyl)methylamino]-2-hex-1-ynylpurin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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C24H26BrN5O2
 1
1
Ki = 59 nM
   TI
   LI
   LO
   TS
CP0395293
(1R,2R,3S,4R,5S)-4-(6-amino-2-hex-1-ynylpurin-9-yl)bicyclo[3.1.0]hexane-2,3-diol
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C17H21N5O2
 1
1
Ki = 65 nM
   TI
   LI
   LO
   TS
CP0467103
3'-amino-3'-deoxyadenosine
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C10H14N6O3
 1
1
Ki = 84 nM
   TI
   LI
   LO
   TS
CP0433444
(1R,2R,3S,4R,5S)-4-[6-(ethylamino)-2-hex-1-ynylpurin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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C19H25N5O2
 1
1
Ki = 176 nM
   TI
   LI
   LO
   TS
CP0395291
(1R,2R,3S,4R,5S)-4-[2-hex-1-ynyl-6-(methylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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C18H23N5O2
 1
1
Ki = 231 nM
   TI
   LI
   LO
   TS
CP0257633
(2R,3S,4R,5R)-2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol
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C10H14N6O3
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
CP0409614
4-Amino-2-(6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3-ol
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C15H22N6O3
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
CP0430608
2'-AMINO-2'-DEOXYADENOSINE
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C10H14N6O3
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Peripheral blood)
Cell Line Name Organism Disease
SET-2 Homo sapiens (Human) Adult acute megakaryoblastic leukemia
Mono-Mac-6 Homo sapiens (Human) Adult acute monocytic leukemia
HL-60 Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-13 Homo sapiens (Human) Adult acute myeloid leukemia
OCI-AML-2 Homo sapiens (Human) Adult acute myeloid leukemia
HL-60/ADR Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-14 Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MDR Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MRP Homo sapiens (Human) Adult acute myeloid leukemia
NALM-6 Homo sapiens (Human) Adult B acute lymphoblastic leukemia
MOLT-4 Homo sapiens (Human) Adult T acute lymphoblastic leukemia
MOLT-4/CCR5 Homo sapiens (Human) Adult T acute lymphoblastic leukemia
Karpas-299 Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
M-07e Homo sapiens (Human) Childhood acute megakaryoblastic leukemia
THP-1 Homo sapiens (Human) Childhood acute monocytic leukemia
MV4-11 Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual KO-STING Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Blue ISG Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-ASC-GFP Homo sapiens (Human) Childhood acute monocytic leukemia
PMNL Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Xblue Homo sapiens (Human) Childhood acute monocytic leukemia
SEM Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SEMK2 Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Reh Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Jurkat Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
Jurkat E6.1 Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-CEM Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF/VCR1000 Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB100 Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB500 Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-SS Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
HPB-ALL Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-SB Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-T4 Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
J-Lat 10.6 Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
12D7-MDR1 Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
MDR CCRF vcr1000 Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
FGS7 Jurkat Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
EoL-1 Homo sapiens (Human) Chronic eosinophilic leukemia, not otherwise specified
CII Homo sapiens (Human) Chronic lymphocytic leukemia
Ku812 Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
Ri-1 Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
Daudi Homo sapiens (Human) EBV-related Burkitt lymphoma
HEL Homo sapiens (Human) Erythroleukemia
UKE-1 Homo sapiens (Human) Essential thrombocythemia
L-1236 Homo sapiens (Human) Hodgkin lymphoma
Granta-519 Homo sapiens (Human) Mantle cell lymphoma
JeKo-1 Homo sapiens (Human) Mantle cell lymphoma
Mino Homo sapiens (Human) Mantle cell lymphoma
HMC-1 Homo sapiens (Human) Mast cell leukemia
NK-92 Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
NK Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1 Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226 Homo sapiens (Human) Plasma cell myeloma
OPM-2 Homo sapiens (Human) Plasma cell myeloma
U266B1 Homo sapiens (Human) Plasma cell myeloma
KMS-18 Homo sapiens (Human) Plasma cell myeloma
MM1.S Homo sapiens (Human) Plasma cell myeloma
MM1.R Homo sapiens (Human) Plasma cell myeloma
OPM-1 Homo sapiens (Human) Plasma cell myeloma
RPMI-8226/Dox40 Homo sapiens (Human) Plasma cell myeloma
HuT 78 Homo sapiens (Human) Sezary syndrome
H9 Homo sapiens (Human) Sezary syndrome
CREM010i-SS9-1 Homo sapiens (Human) Sickle cell disease
RBL-1 Rattus norvegicus (Rat) Rat leukemia
LCL Orang Asli K28 Homo sapiens (Human) -
JY Homo sapiens (Human) -
C.M.L. Homo sapiens (Human) -
BON Homo sapiens (Human) -
PBMC iPSC #1 Homo sapiens (Human) -
LCL 721 Homo sapiens (Human) -