Brief Information of the Cell Line and Protein
Cell Line ID: CL000278 , RBL-2H3
Synonyms
RBL2H3
RBL 2H3
RBL.2H3
Category Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0591
Protein ID: PT06075 , Tyrosine-protein kinase SYK
Gene Name SYK
Organism Rattus norvegicus, Rat
Protein Classification Kinase
Uniprot ID Q64725
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000278  Protein ID: PT06075
 
Compound ID Compound Name Compound Formula
CP0259173
3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)-N-methyl-2-oxoindoline-5-carboxamide
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C21H19N3O3
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0130033
3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide
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C20H19N3O4S
 1
1
EC50 = 110 nM
   TI
   LI
   LO
   TS
CP0016242
3-((1-methyl-1H-indol-3-yl)methylene)-2-oxoindoline-5-sulfonamide
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C18H15N3O3S
 1
1
EC50 = 313 nM
   TI
   LI
   LO
   TS
CP0320547
3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)-2-oxoindoline-5-carboxylic acid
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C20H16N2O4
 1
1
EC50 = 3500 nM
   TI
   LI
   LO
   TS
CP0170330
3-((1-(3-hydroxypropyl)-5-methoxy-1H-indol-3-yl)methylene)-2-oxoindoline-5-sulfonamide
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C21H21N3O5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0259174
4-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indol-(3Z)-ylidenemethyl]-indol-1-yl}-butyramide
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C22H22N4O5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0853513
10-(3-aminopropyl)-3,4-dimethylacridin-9(10H)-one oxalate
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C20H22N2O5
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS