General Information of the Compound
| Compound ID |
CP0016242
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| Compound Name |
3-((1-methyl-1H-indol-3-yl)methylene)-2-oxoindoline-5-sulfonamide
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| Synonyms |
CG-103065
Syk inhibitor (inflammation/cancer)
Syk inhibitor (inflammation/cancer), CG Pharmaceuticals
Syk inhibitors (inflammation/cancer), CG Pharmaceuticals
Syk inhibitors (inflammation/cancer), CrystalGenomics
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| Structure |
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| Formula |
C18H15N3O3S
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| Molecular Weight |
353.403
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| Canonical SMILES |
Cn1cc(\C=C2/C(=O)Nc3ccc(cc23)S(N)(=O)=O)c2ccccc12
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| InChI |
InChI=1S/C18H15N3O3S/c1-21-10-11(13-4-2-3-5-17(13)21)8-15-14-9-12(25(19,23)24)6-7-16(14)20-18(15)22/h2-10H,1H3,(H,20,22)(H2,19,23,24)/b15-8-
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| InChIKey |
MLKHXLFEYOOYEY-NVNXTCNLSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound