Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000071
Cell Line Name	MOLM-13
Synonyms	MOLM13 Molm13 Molm 13
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_2119
Tissue Information	Peripheral blood
Disease	Adult acute myeloid leukemia (NCIt: C9154) Myelodysplastic syndrome (NCIt: C3247) Acute myeloid leukemia (ORDO: Orphanet_519)

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT05070, N6-adenosine-methyltransferase catalytic subunit

Protein Info

Compound ID	Compound Name	Compound Formula
CP0034575 Compound Info	4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]-2,5-difluorophenyl]-9-[6-(methylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one Show/Hide	C27H37F2N7O	1
1	EC50 = 850 nM Bioactivity Info	TI LI LO TS
CP0770003 Compound Info	(2R,3R,4S,5R)-2-(4-amino-5-chloro-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3,4-diol Show/Hide	C21H21ClN6O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0770005 Compound Info	(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(2-pyrrolidin-1-yl-7-quinolyl)oxymethyl]tetrahydrofuran-3,4-diol Show/Hide	C24H26N6O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0770069 Compound Info	(1R,2S,3R,5S)-3-(4-amino-5-cyclohexyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[2-(methylamino)-7-quinolyl]ethyl]cyclopentane-1,2-diol Show/Hide	C29H36N6O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0776534 Compound Info	(2R,3R,4S,5R)-2-(4-amino-5-cyclopentyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[2-(methylamino)-7-quinolyl]ethyl]tetrahydrofuran-3,4-diol Show/Hide	C27H32N6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0826631 Compound Info	(1R,2S,3R,5S)-3-(4-amino-5-cyclopentyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[2-(ethylamino)-7-quinolyl]ethyl]cyclopentane-1,2-diol Show/Hide	C29H36N6O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0833955 Compound Info	(2R,3R,4S,5R)-5-(4-amino-5-chloro-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C21H20ClFN6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0835373 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(1-methylimidazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(ethylamino)-7-quinolyl]oxymethyl]-4-fluoro-tetrahydrofuran-3-ol Show/Hide	C26H27FN8O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0835374 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(1-methylimidazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C25H25FN8O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0835441 Compound Info	(2R,3R,4S,5R)-2-(4-amino-5-bromo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3,4-diol Show/Hide	C21H21BrN6O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0835446 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(3-methylpyrazol-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(azetidin-1-yl)-7-quinolyl]oxymethyl]-4-fluoro-tetrahydrofuran-3-ol Show/Hide	C27H27FN8O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0836897 Compound Info	(2R,3S,5R)-5-(4-amino-5-chloro-pyrrolo[2,3-d]pyrimidin-7-yl)-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C21H21ClN6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0838648 Compound Info	(1R,2S,3R,5S)-3-(4-amino-5-methyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[2-(methylamino)-7-quinolyl]ethyl]cyclopentane-1,2-diol Show/Hide	C24H28N6O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0944329 Compound Info	(2R,3R,4S,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C21H21FN6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0944330 Compound Info	(1R,2S,3R,5S)-3-[4-amino-5-(hydroxymethyl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-[2-[2-(methylamino)-7-quinolyl]ethyl]cyclopentane-1,2-diol Show/Hide	C24H28N6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0944332 Compound Info	(2R,3R,4S,5R)-5-(4-amino-5-chloro-pyrrolo[2,3-d]pyrimidin-7-yl)-2-[[2-(ethylamino)-7-quinolyl]oxymethyl]-4-fluoro-tetrahydrofuran-3-ol Show/Hide	C22H22ClFN6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0944383 Compound Info	(2R,3R,4S,5R)-2-(4-amino-5-cyclohexyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3,4-diol Show/Hide	C27H32N6O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0951031 Compound Info	(2R,3R,4S,5R)-2-[4-amino-5-(cyclopentylmethyl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3,4-diol Show/Hide	C27H32N6O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0952962 Compound Info	(2R,3S,5R)-5-(4-amino-5-cyclopentyl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C26H30N6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0952963 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(1H-pyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C24H23FN8O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0966429 Compound Info	(1S,2S,4R)-4-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[2-[2-(azetidin-1-yl)-7-quinolyl]ethyl]cyclopentanol Show/Hide	C29H32N8O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0967182 Compound Info	(1S,2R,4R)-4-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(azetidin-1-yl)-7-quinolyl]oxymethyl]cyclopentanol Show/Hide	C28H30N8O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968130 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-[(2R)-tetrahydrofuran-2-yl]pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C25H27FN6O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968178 Compound Info	(2R,3R,4S,5R)-2-(4-amino-5-cyclopentyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[[2-(dimethylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3,4-diol Show/Hide	C27H32N6O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968179 Compound Info	1-[7-[[(2R,3R,4S,5R)-5-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-3-hydroxy-tetrahydrofuran-2-yl]methoxy]-2-quinolyl]azetidin-3-ol Show/Hide	C27H27FN8O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968361 Compound Info	(2R,3R,4S,5R)-5-(4-amino-5-cyclopentyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C26H29FN6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968362 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(cyclopropylmethyl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C25H27FN6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968363 Compound Info	(2R,3R,4S,5R)-5-(4-amino-5-bromo-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C21H20BrFN6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968364 Compound Info	(1R,2S,3R,5S)-3-(4-amino-5-cyclopentyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[2-(methylamino)-7-quinolyl]ethyl]cyclopentane-1,2-diol Show/Hide	C28H34N6O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968494 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(2-pyridyl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C26H24FN7O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968495 Compound Info	(2R,3R,4S,5R)-5-(4-amino-5-cyclopropyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C24H25FN6O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0969676 Compound Info	(2R,3S,5R)-5-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(cyclopropylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C27H28N8O3	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0950524 Compound Info	N1-(7-((5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-isopropylquinazolin-4-yl)-N2,N2-dimethylethane-1,2-diamine Show/Hide	C27H31N9O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0950525 Compound Info	7-((5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-ethyl-N-(2-methoxyethyl)-1,5-naphthyridin-4-amine Show/Hide	C29H30N10O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0951110 Compound Info	7-((5-(4-amino-5-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-ethylquinolin-2-amine Show/Hide	C23H20ClN7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0951111 Compound Info	7-(5-(((2-isopropyl-4-(piperazin-1-yl)quinolin-7-yl)oxy)methyl)pyridin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C28H30N8O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0955815 Compound Info	7-(5-(((2-ethyl-4-morpholinoquinolin-7-yl)oxy)methyl)pyridin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C27H27N7O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0959226 Compound Info	7-((5-(4-amino-5-(cyclopropylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C26H25N7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0959228 Compound Info	7-((5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C22H19N7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0959229 Compound Info	N1-(7-((5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-cyclobutylquinolin-4-yl)-N2,N2-dimethylethane-1,2-diamine Show/Hide	C29H32N8O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0959230 Compound Info	(R)-7-((5-(4-amino-5-(tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C26H25N7O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0961088 Compound Info	7-((5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-cyclopropyl-2-ethyl-N-methylquinolin-4-amine Show/Hide	C31H31N9O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0964517 Compound Info	7-((5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-(cyclopropylmethyl)-2-ethyl-N-methylquinolin-4-amine Show/Hide	C32H33N9O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0965015 Compound Info	7-(5-(2-(2-(azetidin-1-yl)quinolin-7-yl)ethyl)pyridin-3-yl)-5-(tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C29H29N7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0965162 Compound Info	7-((5-(4-amino-5-cyclopentyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C27H27N7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0965163 Compound Info	N1-(7-(2-(5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)ethyl)-2-ethylquinolin-4-yl)-N1,N2,N2-trimethylethane-1,2-diamine Show/Hide	C33H38N10	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0965370 Compound Info	7-((5-(4-amino-5-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-ethylquinolin-4-amine Show/Hide	C28H29N7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0965372 Compound Info	7-((5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-ethylquinolin-2-amine Show/Hide	C27H25N9O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0966493 Compound Info	7-((5-(4-amino-5-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C27H27N7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0967202 Compound Info	7-((6-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyrazin-2-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C21H18N8O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968019 Compound Info	7-((5-(4-amino-6-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C23H21N7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968020 Compound Info	7-((5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-ethyl-N-methylquinolin-4-amine Show/Hide	C28H27N9O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0968045 Compound Info	7-((6-(4-amino-5-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyrazin-2-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C21H17ClN8O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0969589 Compound Info	7-(2-(5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)ethyl)-N-methylquinolin-2-amine Show/Hide	C23H21N7	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0970532 Compound Info	7-((5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-ethyl-N-(2-methoxyethyl)quinolin-4-amine Show/Hide	C26H27N7O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0970535 Compound Info	7-((5-(4-amino-5-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C22H18ClN7O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0970536 Compound Info	7-(2-(6-(4-amino-5-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyrazin-2-yl)ethyl)-N-methylquinolin-2-amine Show/Hide	C27H28N8	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0970538 Compound Info	7-(5-(((2-ethyl-4-(piperazin-1-yl)quinolin-7-yl)oxy)methyl)pyridin-3-yl)-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C31H32N10O	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0970540 Compound Info	N1-(7-(2-(5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)ethyl)-2-ethyl-5-fluoroquinolin-4-yl)-N2,N2-dimethylethane-1,2-diamine Show/Hide	C32H35FN10	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0970541 Compound Info	7-((5-(4-amino-5-(5-methylfuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C27H23N7O2	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0970542 Compound Info	7-((5-(4-amino-5-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine 2,2,2-trifluoroacetate Show/Hide	C32H31F3N8O6S	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0835370 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-ethyl-4-(methylamino)-7-quinolyl]oxymethyl]-4-fluoro-tetrahydrofuran-3-ol Show/Hide	C27H29FN8O3	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0951032 Compound Info	(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[[2-(dimethylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3,4-diol Show/Hide	C22H24N6O4	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0967181 Compound Info	(1R,2S,3R,5S)-3-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[2-(dimethylamino)-7-quinolyl]ethyl]cyclopentane-1,2-diol Show/Hide	C24H28N6O2	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0969675 Compound Info	(1R,2S,3R,5S)-3-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-(2-pyridyl)ethyl]cyclopentane-1,2-diol Show/Hide	C18H21N5O2	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0951109 Compound Info	7-((6-(4-amino-5-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyrazin-2-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C26H26N8O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0953221 Compound Info	7-(5-(((2-(azetidin-1-yl)quinolin-7-yl)oxy)methyl)pyridin-3-yl)-5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C24H20ClN7O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0953222 Compound Info	7-((5-(4-amino-5-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-ethylquinolin-4-amine Show/Hide	C23H20ClN7O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0959225 Compound Info	7-((5-(4-amino-6-methyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C23H21N7O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0959227 Compound Info	7-((5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-ethylquinolin-4-amine Show/Hide	C23H21N7O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0959231 Compound Info	N1-(7-((5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-ethyl-5-fluoroquinolin-4-yl)-N2,N2-dimethylethane-1,2-diamine Show/Hide	C31H33FN10O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0961090 Compound Info	6-(3-(4-amino-5-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)-N-methylquinolin-2-amine Show/Hide	C24H21ClN6	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0968018 Compound Info	(3-(4-amino-5-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(((2-(methylamino)quinolin-7-yl)oxy)methyl)phenyl)methanol Show/Hide	C24H21ClN6O2	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0968021 Compound Info	7-((5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methyl-4-(3-morpholinopropyl)quinolin-2-amine Show/Hide	C29H32N8O2	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0969588 Compound Info	7-((5-(4-amino-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C23H21N7O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0969845 Compound Info	(3-(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(((2-(methylamino)quinolin-7-yl)oxy)methyl)phenyl)methanol Show/Hide	C24H22N6O2	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0969846 Compound Info	7-((5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-ethyl-N,N-dimethylquinolin-4-amine Show/Hide	C29H29N9O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0970533 Compound Info	7-((5-(4-amino-5-(1-methyl-1H-pyrazol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C26H23N9O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0970534 Compound Info	7-((5-(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C22H19N7O	1
1	IC50 >= 10000 nM Bioactivity Info	TI LI LO TS
CP0176621 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(4-methyl-1,3-oxazol-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(azetidin-1-yl)quinolin-7-yl]oxymethyl]-4-fluorooxolan-3-ol Show/Hide	C27H26FN7O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0355719 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-[(2S)-oxolan-2-yl]pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(azetidin-1-yl)quinolin-7-yl]oxymethyl]-4-fluorooxolan-3-ol Show/Hide	C27H29FN6O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0423534 Compound Info	(2R,3R,4S,5R)-2-(4-amino-5-cyclopentylpyrrolo[2,3-d]pyrimidin-7-yl)-5-[[2-(ethylamino)quinolin-7-yl]oxymethyl]oxolane-3,4-diol Show/Hide	C27H32N6O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0444463 Compound Info	(2R,3R,4S,5R)-2-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-[[2-(methylamino)quinolin-7-yl]oxymethyl]oxolane-3,4-diol Show/Hide	C25H26N8O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0444464 Compound Info	(2R,3R,4S,5R)-5-(4-amino-5-pyrazol-1-ylpyrrolo[2,3-d]pyrimidin-7-yl)-2-[[2-(azetidin-1-yl)quinolin-7-yl]oxymethyl]-4-fluorooxolan-3-ol Show/Hide	C26H25FN8O3	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0562953 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(5-methylfuran-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)quinolin-7-yl]oxymethyl]oxolan-3-ol Show/Hide	C26H25FN6O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0833923 Compound Info	(2R,3R,4S,5R)-5-(4-amino-5-oxazol-2-yl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C24H22FN7O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0835466 Compound Info	(2R,3R,4S,5R)-2-(4-amino-5-cyclopentyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3,4-diol Show/Hide	C26H30N6O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0944331 Compound Info	(2R,3S,5R)-5-(4-amino-5-pyrazol-1-yl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-[[2-(azetidin-1-yl)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C26H26N8O3	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0966428 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C25H25FN8O3	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0967183 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(cyclobutylamino)-7-quinolyl]oxymethyl]-4-fluoro-tetrahydrofuran-3-ol Show/Hide	C28H29FN8O3	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0968081 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(azetidin-1-yl)-7-quinolyl]oxymethyl]-4-fluoro-tetrahydrofuran-3-ol Show/Hide	C27H27FN8O3	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0968365 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-[(2R)-tetrahydrofuran-2-yl]pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(azetidin-1-yl)-7-quinolyl]oxymethyl]-4-fluoro-tetrahydrofuran-3-ol Show/Hide	C27H29FN6O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0968366 Compound Info	(2R,3S,5R)-5-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-2-[[2-(azetidin-1-yl)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C27H28N8O3	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0969275 Compound Info	(2R,3R,4S,5R)-5-[4-amino-5-[(2S)-tetrahydrofuran-2-yl]pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol Show/Hide	C25H27FN6O4	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0951112 Compound Info	7-(2-(5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)ethyl)-N-ethylquinolin-2-amine Show/Hide	C28H27N9	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0953223 Compound Info	7-(2-(5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)ethyl)-2-ethyl-N-(2-methoxyethyl)-N-methylquinolin-4-amine Show/Hide	C32H35N9O	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0961089 Compound Info	(S)-7-(5-(((2-(azetidin-1-yl)quinolin-7-yl)oxy)methyl)pyridin-3-yl)-5-(tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C28H27N7O2	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0965371 Compound Info	7-(5-(2-(2-(azetidin-1-yl)quinolin-7-yl)ethyl)pyridin-3-yl)-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C29H27N9	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0966490 Compound Info	(S)-7-((5-(4-amino-5-(tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-N-methylquinolin-2-amine Show/Hide	C26H25N7O2	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0968044 Compound Info	7-(2-(5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)ethyl)-N-methylquinolin-2-amine Show/Hide	C27H25N9	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0970537 Compound Info	7-(2-(5-(4-amino-5-(1-methyl-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)ethyl)-2-ethyl-N-(2-methoxyethyl)quinolin-4-amine Show/Hide	C31H33N9O	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0970539 Compound Info	7-(5-(((2-(azetidin-1-yl)quinolin-7-yl)oxy)methyl)pyridin-3-yl)-5-(1-(2-methoxyethyl)-1H-pyrazol-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C30H29N9O2	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS

Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3

Protein Info

Cell Viability or Cytotoxicity Assay

Compound ID	Compound Name	Compound Formula
CP0000866 Compound Info	6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one Hydrochloride Show/Hide	C24H29N7O2	1
1	IC50 = 96 nM	TI LI LO TS
CP0007430 Compound Info	IBRUTINIB Show/Hide	C25H24N6O2	1
1	GI50 = 1300 nM	TI LI LO TS
CP0007710 Compound Info	2-[[1-[2-fluoro-4-[[5-methyl-4-(1-propan-2-ylpyrazol-4-yl)pyrimidin-2-yl]amino]phenyl]piperidin-4-yl]-methylamino]ethanol Show/Hide	C25H34FN7O	1
1	IC50 = 72 nM	TI LI LO TS
CP0016229 Compound Info	N-[5-[4-[[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]methyl]phenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide Show/Hide	C31H37N7O5	1
1	GI50 = 3 nM	TI LI LO TS
CP0016677 Compound Info	N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide Show/Hide	C35H30N4O4	1
1	GI50 = 55 nM	TI LI LO TS
CP0036099 Compound Info	1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea Show/Hide	C21H18FN5O	1
1	GI50 = 37 nM	TI LI LO TS
CP0047745 Compound Info	N-[5-[4-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide Show/Hide	C27H28N6O3S	1
1	GI50 = 50 nM	TI LI LO TS
CP0081835 Compound Info	(2R)-1-(methylamino)-3-[5-[[4-(1,3-thiazol-2-yl)phenyl]methoxy]-3,4-dihydro-1H-isoquinolin-2-yl]propan-2-ol Show/Hide	C23H27N3O2S	1
1	IC50 = 6930 nM	TI LI LO TS
CP0088050 Compound Info	US9447092, 1 Show/Hide	C22H23Cl2N7	1
1	GI50 = 0.104 nM	TI LI LO TS
CP0111104 Compound Info	(2S)-2-amino-N-[5-[6-chloro-5-[(3-methylphenyl)sulfonylamino]pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl]-3-methylbutanamide Show/Hide	C21H24ClN5O3S2	1
1	GI50 = 3000 nM	TI LI LO TS
CP0190889 Compound Info	N-[3-[3-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]benzenesulfonamide Show/Hide	C25H28N8O2S	1
1	GI50 = 21 nM	TI LI LO TS
CP0278627 Compound Info	benzyl N-[[4-[3-[[4-(2-pyrrolidin-1-ylethoxy)benzoyl]amino]-1H-pyrazol-5-yl]phenyl]methyl]carbamate Show/Hide	C31H33N5O4	1
1	GI50 = 2 nM	TI LI LO TS
CP0381229 Compound Info	4-(4-methylpiperazin-1-yl)-N-[5-[4-(phenylcarbamoylamino)phenyl]-1H-pyrazol-3-yl]benzamide Show/Hide	C28H29N7O2	1
1	GI50 = 6 nM	TI LI LO TS
CP0381230 Compound Info	N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]-3-methylphenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide Show/Hide	C31H37N7O5	1
1	GI50 = 8 nM	TI LI LO TS
CP0381463 Compound Info	N-[5-[3-methyl-4-[(5-methyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide Show/Hide	C27H30N8O3	1
1	GI50 = 1 nM	TI LI LO TS
CP0387624 Compound Info	N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(2-pyrrolidin-1-ylethoxy)benzamide Show/Hide	C28H29N5O4S	1
1	GI50 = 25 nM	TI LI LO TS
CP0387627 Compound Info	N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide Show/Hide	C27H28N6O3S	1
1	GI50 = 21 nM	TI LI LO TS
CP0387628 Compound Info	N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-morpholin-4-ylbenzamide Show/Hide	C26H25N5O4S	1
1	GI50 = 100 nM	TI LI LO TS
CP0387629 Compound Info	N-[3-[3-[[6-[2-(dimethylamino)ethylamino]-2-methylpyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]benzenesulfonamide Show/Hide	C24H28N8O2S	1
1	GI50 = 180 nM	TI LI LO TS
CP0397401 Compound Info	N-[5-[4-[[(5-methyl-1,2-oxazol-3-yl)carbamoylamino]methyl]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide Show/Hide	C27H30N8O3	1
1	GI50 = 2 nM	TI LI LO TS
CP0397497 Compound Info	N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(2-pyrrolidin-1-ylethoxy)benzamide Show/Hide	C30H35N7O4	1
1	GI50 = 2 nM	TI LI LO TS
CP0397498 Compound Info	N-[5-[4-[(5-methyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide Show/Hide	C26H28N8O3	1
1	GI50 = 3 nM	TI LI LO TS
CP0404113 Compound Info	2-N-(6-aminohexyl)-9-cyclopentyl-6-N-[4-(morpholin-4-ylmethyl)phenyl]purine-2,6-diamine Show/Hide	C27H40N8O	1
1	GI50 = 54 nM	TI LI LO TS
CP0408781 Compound Info	CHEMBL4204373 Show/Hide	C27H38N8O	1
1	GI50 = 1 nM	TI LI LO TS
CP0414701 Compound Info	1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[[4-[3-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]methyl]urea Show/Hide	C29H38N10O3	1
1	GI50 = 5 nM	TI LI LO TS
CP0417637 Compound Info	4-[acetyl-[(4-tert-butylphenyl)methyl]amino]-N-hydroxybenzamide Show/Hide	C20H24N2O3	1
1	IC50 = 10600 nM	TI LI LO TS
CP0425463 Compound Info	4-(4-methylpiperazin-1-yl)-N-[5-[3-(propylsulfonylamino)phenyl]-1H-pyrazol-3-yl]benzamide Show/Hide	C24H30N6O3S	1
1	GI50 = 56 nM	TI LI LO TS
CP0425464 Compound Info	N-[3-[3-[[2-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]benzenesulfonamide Show/Hide	C26H30N8O3S	1
1	GI50 = 460 nM	TI LI LO TS
CP0425465 Compound Info	N-[5-[3-[(4-chlorophenyl)sulfonylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide Show/Hide	C27H27ClN6O3S	1
1	GI50 = 74 nM	TI LI LO TS
CP0425466 Compound Info	N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide Show/Hide	C28H29N5O5S	1
1	GI50 = 72 nM	TI LI LO TS
CP0429466 Compound Info	N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide Show/Hide	C30H36N8O3	1
1	GI50 = 1 nM	TI LI LO TS
CP0435673 Compound Info	4-[[2-[(4-fluorophenyl)sulfonyl-[(2,3,4,5,6-pentafluorophenyl)methyl]amino]acetyl]-methylamino]-N-hydroxybenzamide Show/Hide	C23H17F6N3O5S	1
1	IC50 = 14100 nM	TI LI LO TS
CP0459938 Compound Info	N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-3-morpholin-4-ylbenzamide Show/Hide	C26H25N5O4S	1
1	GI50 = 260 nM	TI LI LO TS
CP0473577 Compound Info	N-[3-[3-[[2-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]benzenesulfonamide Show/Hide	C27H32N8O3S	1
1	GI50 = 380 nM	TI LI LO TS
CP0475515 Compound Info	tert-butyl N-[(4-tert-butylphenyl)methyl]-N-[4-(hydroxycarbamoyl)phenyl]carbamate Show/Hide	C23H30N2O4	1
1	IC50 = 10300 nM	TI LI LO TS
CP0512765 Compound Info	N-[5-(3-aminophenyl)-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide Show/Hide	C21H24N6O	1
1	GI50 = 77 nM	TI LI LO TS
CP0549768 Compound Info	2-[4-(2-fluorophenoxy)phenyl]-7-(1-prop-2-ynoylpiperidin-4-yl)-5H-imidazo[1,2-b]pyrazole-3-carboxamide Show/Hide	C26H22FN5O3	1
1	IC50 = 711 nM	TI LI LO TS
CP0559800 Compound Info	2-N-(4-aminobutyl)-9-cyclopentyl-6-N-(4-morpholin-4-ylphenyl)purine-2,6-diamine Show/Hide	C24H34N8O	1
1	GI50 = 17 nM	TI LI LO TS

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Peripheral blood)

Cell Line Name		Organism	Disease
SET-2	Cell Line Info	Homo sapiens (Human)	Adult acute megakaryoblastic leukemia
Mono-Mac-6	Cell Line Info	Homo sapiens (Human)	Adult acute monocytic leukemia
HL-60	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
OCI-AML-2	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
HL-60/ADR	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
MOLM-14	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
HL60/MDR	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
HL60/MRP	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
NALM-6	Cell Line Info	Homo sapiens (Human)	Adult B acute lymphoblastic leukemia
MOLT-4	Cell Line Info	Homo sapiens (Human)	Adult T acute lymphoblastic leukemia
MOLT-4/CCR5	Cell Line Info	Homo sapiens (Human)	Adult T acute lymphoblastic leukemia
Karpas-299	Cell Line Info	Homo sapiens (Human)	Anaplastic large cell lymphoma, ALK-positive
M-07e	Cell Line Info	Homo sapiens (Human)	Childhood acute megakaryoblastic leukemia
THP-1	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
MV4-11	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-Dual	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-Dual KO-STING	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-Blue ISG	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-ASC-GFP	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
PMNL	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-Xblue	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
SEM	Cell Line Info	Homo sapiens (Human)	Childhood B acute lymphoblastic leukemia
SEMK2	Cell Line Info	Homo sapiens (Human)	Childhood B acute lymphoblastic leukemia
Reh	Cell Line Info	Homo sapiens (Human)	Childhood B acute lymphoblastic leukemia
Jurkat	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
Jurkat E6.1	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CCRF-CEM	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CCRF/VCR1000	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CEM/VLB100	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CEM/VLB500	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CEM-SS	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
HPB-ALL	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CCRF-SB	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CEM-T4	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
J-Lat 10.6	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
12D7-MDR1	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
MDR CCRF vcr1000	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
FGS7 Jurkat	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
EoL-1	Cell Line Info	Homo sapiens (Human)	Chronic eosinophilic leukemia, not otherwise specified
CII	Cell Line Info	Homo sapiens (Human)	Chronic lymphocytic leukemia
Ku812	Cell Line Info	Homo sapiens (Human)	Chronic myelogenous leukemia, BCR-ABL1 positive
Ri-1	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma activated B-cell type
Daudi	Cell Line Info	Homo sapiens (Human)	EBV-related Burkitt lymphoma
HEL	Cell Line Info	Homo sapiens (Human)	Erythroleukemia
UKE-1	Cell Line Info	Homo sapiens (Human)	Essential thrombocythemia
L-1236	Cell Line Info	Homo sapiens (Human)	Hodgkin lymphoma
Granta-519	Cell Line Info	Homo sapiens (Human)	Mantle cell lymphoma
JeKo-1	Cell Line Info	Homo sapiens (Human)	Mantle cell lymphoma
Mino	Cell Line Info	Homo sapiens (Human)	Mantle cell lymphoma
HMC-1	Cell Line Info	Homo sapiens (Human)	Mast cell leukemia
NK-92	Cell Line Info	Homo sapiens (Human)	Natural killer cell lymphoblastic leukemia/lymphoma
NK	Cell Line Info	Homo sapiens (Human)	Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1	Cell Line Info	Homo sapiens (Human)	Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
OPM-2	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
U266B1	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
KMS-18	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
MM1.S	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
MM1.R	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
OPM-1	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
RPMI-8226/Dox40	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
HuT 78	Cell Line Info	Homo sapiens (Human)	Sezary syndrome
H9	Cell Line Info	Homo sapiens (Human)	Sezary syndrome
CREM010i-SS9-1	Cell Line Info	Homo sapiens (Human)	Sickle cell disease
RBL-1	Cell Line Info	Rattus norvegicus (Rat)	Rat leukemia
RBL-2H3	Cell Line Info	Rattus norvegicus (Rat)	Rat leukemia
LCL Orang Asli K28	Cell Line Info	Homo sapiens (Human)	-
JY	Cell Line Info	Homo sapiens (Human)	-
C.M.L.	Cell Line Info	Homo sapiens (Human)	-
BON	Cell Line Info	Homo sapiens (Human)	-
PBMC iPSC #1	Cell Line Info	Homo sapiens (Human)	-
LCL 721	Cell Line Info	Homo sapiens (Human)	-

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About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han