Brief Information of the Compound and Protein
Compound Name
(2R,3R,4S,5R)-5-[4-amino-5-(1-methylimidazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-[[2-(methylamino)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol
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PubChem ID
CID: 156327117
Canonical SMILES
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cn(C)cn5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1
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Compound Formula C25H25FN8O3
Compound Structure
Protein Name
N6-adenosine-methyltransferase catalytic subunit
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q86U44
Gene Name
METTL3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000071 MOLM-13 Homo sapiens (Human)  1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 10 nM