General Information of the Cell Line
Cell Line ID
CL000776
Cell Line Name
CEM-T4
Synonyms
CEM T4
CemT4
CEMT4
CEM CD4+
Category
Cancer cell line
Organism
Homo sapiens (Human)
Tissue Information
Peripheral blood
Disease
Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00005, Reverse transcriptase/RNaseH
 Protein Info 
Compound ID Compound Name Compound Formula
CP0404227
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-[2-(diethylamino)ethylsulfanyl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C68H124N12O12S
  1
1
IC50 = 2.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0428731
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-27-[2-[methyl(propan-2-yl)amino]ethylsulfanyl]-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C68H124N12O12S
  1
1
IC50 = 19.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0500993
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-27-(2-piperidin-1-ylethylsulfanyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C69H124N12O13S
  1
1
IC50 = 19.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475819
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-[2-[tert-butyl(methyl)amino]ethylsulfanyl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C69H126N12O12S
  1
1
IC50 = 24 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0397292
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-[2-(dimethylamino)ethylsulfanyl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C66H120N12O12S
  1
1
IC50 = 35 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441142
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-[2-[tert-butyl(methyl)amino]ethylsulfanyl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C69H126N12O13S
  1
1
IC50 = 43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0242867
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-[2-(dimethylamino)ethylsulfanyl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C66H120N12O13S
  1
1
IC50 = 45 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0540402
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-[2-(diethylamino)ethylsulfanyl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C68H124N12O13S
  1
1
IC50 = 47 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0404226
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-27-methylsulfanyl-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C63H113N11O12S
  1
1
IC50 = 65.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0535515
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-27-(2-hydroxyethylsulfanyl)-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C64H115N11O13S
  1
1
IC50 = 70 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0529862
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-27-(2-piperidin-1-ylethylsulfanyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C69H124N12O12S
  1
1
IC50 = 72 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418519
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-27-(2-hydroxyethylsulfanyl)-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C64H115N11O14S
  1
1
IC50 = 80 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0409364
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-27-(2-imidazol-1-ylethylsulfanyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C67H117N13O12S
  1
1
IC50 = 80.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0458731
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-27-methylsulfanyl-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C63H113N11O13S
  1
1
IC50 = 84 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441656
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-ethyl-27-(hydroxymethyl)-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C63H113N11O14
  1
1
IC50 = 95 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528943
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-27-(2-morpholin-4-ylethylsulfanyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C68H122N12O13S
  1
1
IC50 = 101 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466774
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C62H111N11O13
  1
1
IC50 = 137.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0403772
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-24-[(2S)-2-methylbutyl]-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C63H113N11O12
  1
1
IC50 = 293 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0036222
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C62H111N11O12
  1
1
IC50 = 455 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Peripheral blood)
Cell Line Name Organism Disease
SET-2
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
Mono-Mac-6
 Cell Line Info 
Homo sapiens (Human) Adult acute monocytic leukemia
HL-60
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-13
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
OCI-AML-2
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL-60/ADR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-14
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MDR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MRP
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
NALM-6
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
MOLT-4
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
MOLT-4/CCR5
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
Karpas-299
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
M-07e
 Cell Line Info 
Homo sapiens (Human) Childhood acute megakaryoblastic leukemia
THP-1
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
MV4-11
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Blue ISG
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-ASC-GFP
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
PMNL
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Xblue
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
SEM
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SEMK2
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Reh
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-CEM
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF/VCR1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB100
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB500
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-SS
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
HPB-ALL
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-SB
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
J-Lat 10.6
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
12D7-MDR1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
MDR CCRF vcr1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
FGS7 Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
EoL-1
 Cell Line Info 
Homo sapiens (Human) Chronic eosinophilic leukemia, not otherwise specified
CII
 Cell Line Info 
Homo sapiens (Human) Chronic lymphocytic leukemia
Ku812
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
Ri-1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
Daudi
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HEL
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
UKE-1
 Cell Line Info 
Homo sapiens (Human) Essential thrombocythemia
L-1236
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
Granta-519
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
JeKo-1
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
Mino
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
HMC-1
 Cell Line Info 
Homo sapiens (Human) Mast cell leukemia
NK-92
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
NK
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-2
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
U266B1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-18
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.S
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.R
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
RPMI-8226/Dox40
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
HuT 78
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
H9
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
CREM010i-SS9-1
 Cell Line Info 
Homo sapiens (Human) Sickle cell disease
RBL-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
RBL-2H3
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
LCL Orang Asli K28
 Cell Line Info 
Homo sapiens (Human) -
JY
 Cell Line Info 
Homo sapiens (Human) -
C.M.L.
 Cell Line Info 
Homo sapiens (Human) -
BON
 Cell Line Info 
Homo sapiens (Human) -
PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human) -
LCL 721
 Cell Line Info 
Homo sapiens (Human) -